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Medicine for treating fat liver of obesity and its preparing method

A technology for obese fatty liver and a drug, applied in the field of preparation of the drug, can solve the problems that there is no satisfactory drug, the efficacy of which has yet to be proved, and the like

Inactive Publication Date: 2004-12-29
张晴龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(4) Antioxidants: reduced GSH, taurine, β-carotene, vitamin E, Matodoxin, selenium organic compound (Ebselen), Silymarin and amino steroid derivative Lazaroid, etc., may reduce oxygen stress damage and lipid overload Oxidation-induced liver fibrosis, but definitive efficacy has yet to be proven
[0007] Due to the various etiologies and complex pathogenesis of fatty liver, lipoprotein metabolism disorders involve many factors and links, which are not only reflected at the level of blood circulation, but also at the level of tissues, cells and molecules, especially the relationship between lipid peroxidation, inflammation and fibrosis. After the relationship, people are trying to find drug intervention, but unfortunately there is no satisfactory drug in clinical practice so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Take 1300g of Polygonum cuspidatum, 800g of Pinellia chinensis, 900g of Alisma, 500g of peach kernel, 800g of Shuihonghuazi, 200g of licorice, add 10 times the amount of 75% ethanol, soak for 4 hours, heat and reflux extraction 3 times, each time for 1.5 hours, combine alcohol Extract the liquid, recover ethanol under reduced pressure and concentrate to a relative density of 1.02 (60°C), let stand, filter, concentrate the filtrate under reduced pressure to a relative density of 1.25 (60°C), vacuum-dry, grind into fine powder, and obtain Polygonum cuspidatum Wait for extract powder. Take another 900g of Curcuma, add 10 times the amount of water, extract the volatile oil for 8 hours, and collect the volatile oil for later use; filter the medicinal solution after oil extraction, centrifuge, concentrate to a relative density of 1.20 (60°C), vacuum-dry, and pulverize into fine powder. Get curcuma extract powder. Take 8 times the amount of β-cyclodextrin as the volatile oil,...

Embodiment 2

[0024] Take 1500g of Polygonum cuspidatum, 700g of Pinellia chinensis, 1200g of Alisma chinensis, 300g of peach kernel, 700g of water safflower seed, 200g of licorice, add 12 times the amount of 65% ethanol, soak for 8 hours, heat and reflux extraction twice, 3 hours each time, combine alcohol Extract the liquid, recover the ethanol under reduced pressure and concentrate it to a relative density of 1.08 (60°C), let it stand, filter, concentrate the filtrate under reduced pressure to a relative density of 1.21 (60°C), vacuum-dry it, and grind it into fine powder to obtain Polygonum cuspidatum Wait for extract powder. Take another 900g of Curcuma, add 8 times the amount of water, extract the volatile oil for 10 hours, and collect the volatile oil for later use; filter the medicinal solution after oil extraction, centrifuge, concentrate to a relative density of 1.25 (60°C), vacuum-dry, and pulverize into fine powder. Get curcuma extract powder. Take 10 times the amount of β-cycl...

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PUM

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Abstract

The present invention relates to a medicine for treating fat live of obesity. It is prepared with seven kinds of Chinese medicinal materials including giant knotwood, pinellia tuber, oriental water plantain, zedoary, peach kernel, prince's-feather fruit and licorice. The preparation process is also disclosed. The medicine has the functions of promoting diuresis, eliminating phlegm, promoting blood circulation and elimianting abdominal mass. It is used to treat fat liver of obesity caused by wetness phlegm stasis mainly. Clinical application shows that it has fast and obviously treating effect and no bad reaction.

Description

Technical field [0001] The invention relates to a medicine for treating obese fatty liver, in particular to a Chinese patent medicine prepared from Chinese herbal medicine, and also relates to a preparation method of the medicine. Background technique [0002] Fatty liver is a pathological state in which lipid accumulation in liver cells is caused by various reasons. According to the etiology, fatty liver is divided into obesity, alcohol, post-hepatitis, drug and metabolic. Obese fatty liver accounts for more than 60% of all fatty livers. Fatty liver can lead to low liver function, and become a factor that increases the incidence of diseases such as hyperlipidemia, coronary heart disease, hypertension, and arteriosclerosis. As the disease progresses, fatty liver can lead to liver fibrosis, liver cirrhosis, liver ascites, and even lower liver function, seriously affecting people's health and quality of life. [0003] Regarding the incidence of this disease, it was reported...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P1/16A61P3/04
Inventor 张晴龙
Owner 张晴龙
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