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Chinese medicine drippling pill for treating coronary heart disease and its preparing method

A technique for coronary heart disease and drop pills, which is applied in the field of drop pills for the treatment of coronary heart disease and its preparation, can solve problems such as unretrieved patent information, and achieve the effects of improving bioavailability, fast onset of action, and favorable absorption

Inactive Publication Date: 2006-07-19
张平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Checked the patent information, but no relevant patent information was retrieved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] (0) The prescription ratio of raw materials is

[0065] Salvia 38.4g, Sandalwood 4.3g, Dalbergia 8.5g, Kaevil 6.4g, Nutmeg 12.8g, Jujube 12.8g, Seabuckthorn 12.8g.

[0066] (2) Extraction process

[0067] ①Put the salvia miltiorrhiza, jujube and seabuckthorn into the extractor, add 125ml of 95% ethanol, and soak for 6 hours.

[0068] ②Put sandalwood, balsamic, kaempferol and nutmeg in an extractor with a volatile oil collector, add 250ml of water, extract for 5 hours, and collect 0.5ml of volatile oil. The aqueous extract was filtered and concentrated.

[0069] ③Use 95% ethanol to extract the medicinal dregs after extraction of volatile oil, salvia miltiorrhiza, jujube and seabuckthorn twice for 1 hour each time. Filtrate, combine the filtrates, and concentrate.

[0070] ④ Add 250ml of water to the medicinal residue after alcohol extraction, boil the water twice for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrated solution of ...

Embodiment 2

[0076] (0) The prescription ratio of raw materials is

[0077] Salvia 35g, Sandalwood 3g, Dalbergia 7g, Kaevil 5g, Nutmeg 10g, Jujube 10g, Seabuckthorn 10g.

[0078] (2) Extraction process

[0079] ①Put the salvia miltiorrhiza, jujube and seabuckthorn into the extractor, add 120ml of 95% ethanol, and soak for 5 hours.

[0080] ②Put sandalwood, balsamic, kaempferol and nutmeg in an extractor with a volatile oil collector, add 230ml of water, extract for 4 hours, and collect 0.42ml of volatile oil. The aqueous extract was filtered and concentrated.

[0081] ③Use 95% ethanol to extract the medicinal dregs after extraction of volatile oil, salvia miltiorrhiza, jujube and seabuckthorn twice for 1 hour each time. Filtrate, combine the filtrates, and concentrate.

[0082] ④ Add 230ml of water to the medicinal residue after alcohol extraction, boil the water twice for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrated solution of the water ext...

Embodiment 3

[0088] (0) The prescription ratio of raw materials is

[0089] Salvia 42g, Sandalwood 5g, Dalbergia 10g, Kaevil 8g, Nutmeg 15g, Jujube 15g, Seabuckthorn 15g.

[0090] (2) Extraction process

[0091] ①Put the salvia miltiorrhiza, jujube and seabuckthorn into the extractor, add 135ml of 95% ethanol, and soak for 7 hours.

[0092] ②Put sandalwood, balsamic, kaempferol and nutmeg in an extractor with a volatile oil collector, add 275ml of water, extract for 6 hours, and collect 0.58ml of volatile oil. The aqueous extract was filtered and concentrated.

[0093] ③Use 95% ethanol to extract the medicinal dregs after extraction of volatile oil, salvia miltiorrhiza, jujube and seabuckthorn twice for 1 hour each time. Filtrate, combine the filtrates, and concentrate.

[0094] ④ Add 275ml of water to the dregs after alcohol extraction, boil the water twice for 1.5 hours each time, filter, concentrate the filtrate, and combine with the concentrated solution of the water extract for oi...

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PUM

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Abstract

The Chinese medicine dripping pill for treating coronary heart disease consists of the extractive of Chinese medicine materials sandalwood, dalbergia wood, cyanide, nutmeg, red sage, axillary choerospondias fruit and sea-buckthorn in 17-24 weight portions; and medicinal supplementary material in 17-24 weight portions. In the extractive, volatile oil accounts for 2-2.5 %. The present invention features that the dripping pill connects neotanshionone IIA not less than 1.0 mg / g and total salvianoic acid not less than 14 mg / g. The pharmacological experiment shows that the dripping pill has excellent pharmacological effect.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a drop pill capable of treating coronary heart disease and a preparation method thereof. Background technique [0002] Coronary heart disease is short for coronary heart disease. It is a kind of myocardial ischemia hypoxia or necrosis caused by coronary circulatory disturbance due to fixed (atherosclerosis) or dynamic (vasospasm) stenosis or obstruction, which causes an imbalance between myocardial oxygen supply and demand A type of heart disease, also known as ischemic heart disease. The incidence of coronary heart disease increases with age, and the degree also increases with age. Some data show that since the age of 40, the prevalence of coronary heart disease will double for every 10 years. After the age of 50 for men and 60 for women, coronary arteriosclerosis develops rapidly, and the risk of myocardial infarction also increases ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61K36/725A61K36/53A61K36/48A61K36/185A61K9/20A61P9/10
Inventor 张平
Owner 张平