Auxiliary medicine for treating esophagus cancer and processing method thereof

A technology for adjuvant therapy and esophageal cancer, which can be used in drug combinations, pharmaceutical formulations, anti-tumor drugs, etc., to solve problems such as unsatisfactory long-term efficacy, improve the quality of life with tumors, improve the long-term survival rate, and achieve low prices. Effect

Inactive Publication Date: 2003-06-18
济南市第四人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For patients with esophageal cancer who have lost the chance of surgery in the middle and late stage, the short-term curative effect of Western medicine radiotherapy and chemotherapy is acceptable, but simultaneous administration also brings many toxic and side effects such as bone marrow suppression, abnormal liver and kidney function, and radiation esophagitis, and the long-term curative effect is not good. very ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] The raw material components and parts by weight of the present embodiment are respectively: 40 Radix Ginseng, 46 Salvia Miltiorrhiza, 42 Radix Astragalus, 41 Radix Pseudostellariae, 15 Radix Scutellariae Radix, 44 Miltonia Spatholobus, 36 Hedyotis diffusa, 16 Dendrobium, 18 Bean Roots, Xuan Fu Hua 7, Dai Zhe Shi 16, Zhi Pin Xia 15, Peach Kernel 14, Angelica 12, Yunling 18, Psoralen 24, and Lu Hive 16. In the present embodiment, when processing, at first put Salvia miltiorrhiza, Radix Pinellia, Psoraleae, and Semen Xanthophyll into ethanol and extract twice by heating under reflux for 0.5 hours each time, and combine the extracts twice; and The dregs after ethanol extraction and other ingredients are decocted with water twice, each time for 1.5 hours, the two decoctions are combined, filtered, and allowed to cool; the obtained extracts and decoctions are combined to obtain the original juice of the medicinal liquid; Add ethanol to the original juice to make the ethanol c...

Embodiment 2

[0011] The raw material components and parts by weight of the present embodiment are respectively: 41 Radix Ginseng, 49 Salvia Miltiorrhiza, 44 Radix Astragali, 46 Radix Pseudostellariae, 10 Radix Spatholobus Spatholobus, 41 Hedyotis diffusa, 18 Dendrobium, 20 Rhizoma Radix, Complex flower 22, generation ochre 19, pinellia 13, peach kernel 17, angelica 8, yunling 24, psoralen 17, dew hive 10. When the present embodiment is being processed, at first Salvia miltiorrhiza, pinellia, psoraleae, xanthophyll are put into ethanol and heated under reflux to extract twice, each time for 40 minutes, and the extracts are merged twice; and The dregs and other ingredients after ethanol extraction are decocted twice with water, each time for 1 hour, the two decoctions are combined, filtered, and allowed to cool; the obtained extracts and decoctions are combined to obtain the original juice of the medicinal liquid; Add ethanol to the raw juice to make the ethanol content reach 55%, let it sin...

Embodiment 3

[0013] The raw material components and parts by weight of the present embodiment are respectively: 42 Adenophora miltiorrhiza, 42 salvia miltiorrhiza, 40 Radix Astragali, 42 Radix Pseudostellariae, 18 Radix Spatholobus, 52 Caulis Spatholobus, 38 Hedyotis diffusa, 25 dendrobium, 16 broad bean root, Xuan Fu Hua 18, Dai Zhe Shi 12, Zhi Pinellia 17, Peach Kernel 20, Angelica 11, Yunling 20, Psoralen 25, Dew Honeycomb 6. When the present embodiment is being processed, at first Salvia miltiorrhiza, pinellia, psoraleae, xanthophyll are all put into ethanol and heated under reflux to extract twice, each time 50 minutes, merge twice extracting solution; And The dregs and other ingredients after ethanol extraction are decocted twice with water, each time for 75 minutes, the two decoctions are combined, filtered, and allowed to cool; the obtained extracts and decoctions are combined to obtain the original juice of the medicinal liquid; Add ethanol to the original juice to make the ethano...

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PUM

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Abstract

A Chinese medicine for auxiliary therapy to esophagus cancer is prepared from 17 Chinese-medicinal materials including red sage root, astragalus root, pseudostellaria root, oldenlandia, etc. Its advantages are high effect on relaxing the toxic by-effect caused by chemicotherapy, sure curative effect and low cost.

Description

Technical field [0001] The invention relates to a medicine for auxiliary treatment of esophageal cancer and a processing method thereof. Background technique [0002] Esophageal cancer is a viscous malignant tumor of the esophagus, characterized by dysphagia, and belongs to the category of "choking diaphragm" in traditional Chinese medicine. The etiology is complex and not yet clear. It is generally believed that nitrosamine compounds and molds have carcinogenic effects. Long-term physical stimulation such as hot food, strongly stimulating food, rough food, and eating too fast can cause esophageal epithelial damage, inflammation and hyperplasia, and induce canceration. In addition, it is related to long-term tobacco and alcohol stimulation, lack of trace elements, genetic factors and changes in the living environment. In this disease, squamous cell carcinoma is the most common, more common in the upper and middle segment, followed by adenocarcinoma, more common in the lowe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/26A61K35/64A61P1/00A61P35/00
Inventor 张兆泉杜文建刘立中刘金凤刘静张玉洁
Owner 济南市第四人民医院
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