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Medicinal composition for treating cardio-cerebro-vascular diseases

A technology for cardiovascular and cerebrovascular diseases and compositions, which is applied in the field of pharmaceutical compositions composed of effective parts, can solve problems such as increasing cardiac and cerebral blood flow, and achieve the effects of increasing cardiac and cerebral blood flow, significant curative effect, and increased safety

Inactive Publication Date: 2004-09-15
福州星汉生物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Breviscapine has obvious effects on improving cardiovascular and cerebrovascular circulation and increasing blood flow in the heart and brain. It is an effective preparation for treating cerebral infarction and myocardial infarction. It can reduce peripheral resistance, reduce myocardial oxygen consumption, promote collateral circulation, and inhibit platelet aggregation. It has a good curative effect on cerebral infarction, coronary heart disease, and angina pectoris, but its effect on reducing ischemia-reperfusion injury after cerebral infarction and myocardial infarction is weaker than that of salvianolic acid

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take 10 g of salvianolic acid and 1 g of breviscapine, dissolve them in 1000 ml of water for injection, and use the existing powder injection preparation process to prepare a pharmaceutical composition in powder injection form containing 1 part of salvianolic acid and 0.1 part of breviscapine.

Embodiment 2

[0033] Take 1g of salvianolic acid, 15g of scutellarin, and 25g of vegetable oil, mix them evenly, use gelatin as the capsule shell material, and press them into soft capsules to obtain a drug in the form of soft capsules containing 1 part of salvianolic acid and 15 parts of breviscapine combination.

Embodiment 3

[0035] Take 10 g of salvianolic acid, 2 g of scutellarin, and 100 g of starch, mix them uniformly, and adopt a capsule preparation process to prepare a pharmaceutical composition in capsule form containing 1 part of salvianolic acid and 0.2 part of breviscapine.

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PUM

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Abstract

The present invention discloses a medicine for curing angiocardiopathy and cerebrovascular disease. It is formed from two raw materials of breviscapine and salviod acid extracted from salvia root. Said medicine composition not only can effectively improve cardio-cerebral vascular circulation after cerebral infraction or cardiac infraction, can expand cardiac vessel and blood vessel of brain, increase cardio-serebral blood flow, but also can effectively improve microcirculation and reduce is chemic reperfusion injury after cerebral infraction and cardiac infraction, so that its therapeutic effect can be obviously raised.

Description

Technical field [0001] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases, in particular to a medicine composition composed of scutellarin and effective parts of Danshen. Background technique [0002] Cardiovascular and cerebrovascular diseases are all related to abnormal blood rheology, mainly manifested as "thickness", "stickiness", "coagulation", and "gathering". "Dense" means that the concentration of blood is increased, and the concentration of plasma protein and blood lipid is increased. "Viscous", that is, blood viscosity, manifested as increased viscosity of whole blood and plasma. "Coagulation" refers to the increase of blood coagulation, which is manifested by the increase of plasma fibrinogen and the acceleration of blood coagulation. "Aggregation" refers to increased blood cell aggregation, manifested as slow electrophoresis of red blood cells and platelets in plasma, increased platelet aggregation, and accelerated eryt...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/7048A61P9/10
Inventor 李文军陈谨
Owner 福州星汉生物药业有限公司
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