18 results about "Collateral circulation" patented technology

The invention discloses an intelligent assessment method and system for coronary stenosis based on chest radiography, and relates to the technical field of health risk assessment, and the method comprises the steps: obtaining chest radiography image data of a target patient; based on the time sequence fluctuation of the calcification focus area in the chest radiograph image data, calculating to obtain a calcification activity index, determining a cardiac pulsation key point in the chest radiograph image data, and based on the displacement change of the cardiac pulsation key point between each image frame, calculating to obtain a collateral circulation compensation index of the calcification focus area; based on the collateral circulation compensation index and the calcification activity index, calculating a dynamic risk factor corresponding to the coronary artery stenosis; and inputting the dynamic risk factor into a preset neural network model for iterative training, and performing prediction processing on the chest radiograph image data based on the trained preset neural network model to obtain a coronary artery stenosis risk assessment result. The technical effect of reducing the clinical misjudgment risk of coronary artery stenosis is achieved.

This invention provides an automated evaluation method, apparatus, storage medium, and computing device for intracranial collateral circulation. The method includes: obtaining cerebral blood flow images based on ASL images from multiple PLD times; segmenting the cerebral blood flow images to obtain regions of interest (ROIs) for arterial arrival artifacts; calculating quantitative parameters for evaluating intracranial collateral circulation based on the ROIs; and marking the ROIs and the quantitative parameters in the cerebral blood flow images. The method of this invention can more objectively evaluate the severity of arterial arrival artifacts, thereby evaluating collateral circulation and better assisting physicians in making clearer judgments and analyses of patients' conditions in clinical practice.

The application discloses a kind of based on chest radiograph coronary artery stenosis intelligent evaluation method and system, it is related to health risk assessment technical field, the method includes: obtaining the chest radiograph image data of target patient;Based on the time sequence fluctuation of calcification focus area in chest radiograph image data, the calcification activity index is calculated, determine the heart beat key point in chest radiograph image data, based on the displacement change between each image frame of heart beat key point, the collateral circulation compensation index of calcification focus area is calculated;Based on collateral circulation compensation index and calcification activity index, the dynamic risk factor corresponding to coronary stenosis is calculated;Dynamic risk factor is input to the preset neural network model and is iteratively trained, and based on the preset neural network model after training is completed to chest radiograph image data is predicted to process, obtains coronary stenosis risk assessment result.The application reaches the technical effect of reducing the clinical misjudgment risk of coronary artery stenosis.

The application discloses an acute large blood vessel occlusion identification and reperfusion decision method and system, and the method comprises the following steps: S1, obtaining medical record text and head multi-modal CT image data of a patient to be diagnosed; S2, performing natural language processing on the medical record text to obtain text features; S3, processing the multi-modal CT image data, calculating the ASPECTS score of non-enhanced CT, and positioning the blood vessel occlusion position and evaluating the collateral circulation from the CTA image to obtain image features; S4, performing weighted fusion on the text features and the image features to generate fusion features; and S5, inputting the fusion features into a pre-constructed guideline knowledge graph and a decision model to generate an individualized acute large blood vessel occlusion identification result and a reperfusion treatment suggestion. The application can automatically, quickly and accurately generate an individualized identification result and a treatment suggestion by fusing the features of the medical record text and the multi-modal CT image and combining a real-time updated guideline knowledge graph.

The application discloses a multi-period brain CTA collateral circulation scoring method based on feature fusion under an attention mechanism, and mainly relates to the technical field of computer-aided medical treatment; the method comprises the following steps: S1, converting an original CTA-dicom sequence into a pseudo RGB image; S2, designing four independent single-branch networks according to the data characteristics of multi-period data; S3, fusing multi-period CTA images and enriching data characteristics through the designed single-branch multi-feature fusion and multi-period multi-feature fusion modules; S4, adding a global attention mechanism module to the fused network to add a global feature extraction attention mechanism; and S5, inputting the screened fusion features into a linear classifier to classify the collateral circulation of a patient; the application effectively improves the prognosis judgment efficiency, avoids the limitations of manual extraction of image features in the traditional method, plays an auxiliary role in the diagnosis of doctors in the clinic, and has a guiding role for the clinical treatment decision of collateral circulation stroke.

This invention discloses a method for determining collateral circulation indicators based on single-phase CTA, including acquiring single-phase CTA images and DWI images; preprocessing the images to obtain first images at different levels; registering and identifying the blood-supplying brain tissue regions in the first images at different levels to obtain second images at different levels; identifying the ischemic foci area as the vascular aggregation area based on the DWI images, and mapping the vascular aggregation area to the second images at different levels to obtain third images at different levels; calculating the ratio of the area of ​​the vascular aggregation circle to the area of ​​the healthy side vascular circle in the third images at different levels; calculating the mean value based on the ratio and the number of third images, and determining it as the collateral circulation indicator value of the single-phase CTA image to obtain an intuitive and accurate assessment result. This method can be applied to the field of collateral circulation assessment in acute ischemic stroke based on single-phase CTA.

This invention provides a biomarker for collateral circulation in CTO patients, MIA3, and its application, belonging to the field of biotechnology. This invention reveals and verifies a significant positive correlation between plasma MIA3 levels and the quality of collateral circulation formation in CTO patients, and its predictive efficacy for good collateral circulation is superior to that of the known key angiogenesis factor VEGFA. This allows MIA3 to serve as a high-value, minimally invasive molecular marker for early, non-invasive identification of a patient's collateral circulation formation potential before interventional surgery, thereby enabling risk stratification and providing an objective basis for individualized treatment decisions (such as whether more aggressive intervention is needed). This invention clarifies that MIA3 is a key link in regulating collateral angiogenesis; by targeting and upregulating MIA3 activity, collateral angiogenesis and maturation in ischemic areas can be precisely promoted, providing a novel non-pharmacological, non-surgical treatment strategy for CTO patients.

This application relates to a vascular artificial embolism formation and control system. The system includes an embolism pressure control component, a gas pipeline, a liquid level adjustment component, and a liquid pipeline. The embolism pressure control component controls the gas pressure and volume of the artificial embolism; the liquid level adjustment component includes a liquid extraction control element and a liquid collection container, used to adjust the blood level in the blood vessel after the artificial embolism at the required pressure is formed, thereby controlling the position of the artificial embolism within the blood vessel. This control system can precisely control the gas pressure, gas volume, and position of the artificial embolism in the blood vessel, overcoming the problem of blood backflow during the retrograde movement of the artificial embolism, and significantly reducing the risk of the artificial embolism entering the circulatory system through collateral circulation, effectively preventing the possibility of gas embolism causing harm to other parts of the body; it also reduces the consumption of artificial embolism gas and the loss of blood from the patient during the procedure.

A system is provided for determining a treatment plan for a medical procedure. The system includes a processor configured to generate the treatment plan for the medical procedure. The processor is also configured to obtain images acquired during performance of the medical procedure according to the treatment plan, record progression of the medical procedure based on the images, and extract treatment progress characteristics from the images. The treatment plan may be for treatment of an occlusion and the treatment progress characteristics may include at least one of: (i) occlusion proximal cap morphology, (ii) occlusion length, course, and composition, (iii) quality of a vessel distal to the occlusion, and (iv) collateral circulation. The processor is configured to determine (i) whether to adjust the treatment plan and / or (ii) a treatment selection to use to adjust the treatment plan based on the treatment progress characteristics and the progression of the medical procedure.

The invention discloses a modularized CT perfusion phantom simulating brain tissue and collateral circulation and application, and the phantom is provided with a brain tissue state simulation module which is used for simulating healthy brain tissue, ischemic penumbra and infarction core and is provided with a plurality of independent cavities; the artery input simulation module is used for simulating artery input blood flow, is arranged on the input side of the brain tissue state simulation module in a sealed mode and further communicates with all the cavities; the vein output simulation module is used for simulating vein output blood flow, is arranged on the output side of the brain tissue state simulation module in a sealed mode and further communicates with all the cavities; the collateral circulation module is used for simulating brain collateral circulation. The device is simple in structure and convenient to assemble, cavity filling can be adjusted, and the device can be used for time-density curves and hemodynamic parameters under different injection parameters and flow conditions so as to support CTP protocol optimization, cross-equipment standardization and new algorithm verification.

The invention relates to the technical field of image analysis, in particular to an infarction prediction method and device based on collateral circulation, equipment and a storage medium. According to the invention, the compensation features of collateral circulation are used as conditions to be embedded into the mixed features of the to-be-predicted area, and an infarction lesion perception prediction network and an infarction lesion segmentation network are guided to carry out prediction, so that the adaptability of the prediction method to heterogeneity cases with abundant or deficient collateral circulation compensation is enhanced; and the robustness and the stability of cerebral apoplexy postoperative infarction prediction for different patients are improved.

The invention relates to a blood vessel artificial aeroembolism forming and controlling system. The system comprises an air cock pressure control assembly, a gas pipeline, a liquid level adjusting assembly and a liquid pipeline. The air cock pressure control assembly is used for controlling the air pressure and the air quantity of the artificial air cock; the liquid level adjusting assembly comprises a liquid extraction control part and a liquid collection container and is used for adjusting the liquid level of blood in the blood vessel after the artificial aeroembolism with the needed air pressure is formed in the blood vessel so as to control the position of the artificial aeroembolism entering the blood vessel. The control system can accurately control the air pressure and the air quantity of the artificial aeroembolism and the position of the artificial aeroembolism in the blood vessel, the problem that blood backflow is likely to be caused in the reverse flow moving process of the artificial aeroembolism is solved, and the risk that the artificial aeroembolism enters a blood circulation system in the modes of collateral circulation and the like is remarkably reduced; the possibility that gas embolizes on other parts of the body to cause harm can be effectively prevented; and moreover, the consumption of gas of the artificial aeroembolism and the loss of blood of a patient in an operation are also reduced.

1. Name of the product in this design: Hand Blood Flow Tester. 2. Purpose of this design: To test the blood flow and collateral circulation of the radial and ulnar arteries in the hand, providing a safety basis for radial artery puncture or surgery. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The utility model relates to the technical field of fitness equipment discloses a static exercise chair, including seat body and cushion, the seat body is fixedly installed with the storage frame under the cushion, two baffle are equipped in the storage frame, and two baffle divide the storage frame into the storage compartment and the equipment compartment on the both sides of storage compartment, a equipment compartment is installed with air pump and controller, the output end of air pump is detachably connected with calf air bag, thigh air bag and hip air bag, and the control panel is installed on the two handrails of seat body. The utility model device is associated with seat body as a set of product, and the convenient storage has the function of household product and fitness equipment, and the user can work and exercise simultaneously, the multiple air bags of the device can be inflated simultaneously, which is beneficial to establish lateral circulation to improve the blood supply of ischemic tissue, and the effect is basically equivalent to displacement movement-static running and position static exercise.

The application discloses a brain perfusion parameter prediction blood vessel recanalization grade method and system, and belongs to the technical field of medical image processing. The method comprises the following steps: acquiring a preoperative CTP parameter map and a CTA maximum density projection reconstruction map of an acute large blood vessel occlusive stroke patient and a dynamic scanning sequence of CTP scanning; extracting functional perfusion features from a CTP channel and morphological structure features from a CTA channel through a multi-modal feature fusion network; extracting a collateral compensation vector based on a CTP dynamic sequence through a pre-constructed collateral circulation embedding module; modeling six discrete grades into an ordered category by using an mTICI hierarchical ordered regression prediction head of a cumulative link model; and modulating a prediction output by the collateral compensation vector through an attention gate mechanism, and outputting an mTICI grade prediction probability distribution. The application realizes preoperative prospective prediction of an mTICI grade after mechanical thrombectomy.

This invention provides a biomarker for poor collateral circulation, UBE2L3, and its applications, belonging to the field of biomedical technology. This invention clarifies for the first time the crucial role of UBE2L3 in inhibiting the formation of collateral circulation in chronic total coronary artery occlusion (CTO), and establishes the "UBE2L3-Parkin-Drpl" axis as a key endogenous inhibitory pathway regulating CTO collateral circulation. This provides a clear and well-defined intervention target for developing novel precision therapies that promote therapeutic angiogenesis, solving the problems of unstable efficacy and off-target risks caused by the broad target scope of current pro-angiogenic strategies. It offers a novel non-surgical biological treatment strategy aimed at enhancing endogenous angiogenesis, potentially fundamentally improving myocardial ischemia and thus reducing the risk of long-term adverse events such as myocardial infarction and heart failure.

A method for collateral circulation assessment, using dynamic MRI images, includes the steps of: receiving dynamic perfusion MRI images of a subject by an analysis device; extracting arterial phase images, capillary phase images, and venous phase images from the dynamic perfusion MRI images by the analysis device; inputting the arterial phase images, capillary phase images, and venous phase images into pre-trained, deep learning models, respectively, to calculate a plurality of collateral circulation prediction probability values by the analysis device; and conducting a final collateral circulation assessment for the subject, using the plurality of collateral circulation prediction probability values by the analysis device.

Disclosed in the present invention is an ultrasonic stimulation system for targeted enhancement of collateral circulation for the treatment of ischemic stroke. The system comprises: an ultrasonic stimulation module for generating non-invasive low-frequency ultrasonic waves to stimulate nerves in a specific region on the brain surface, so as to promote the dilation of pial arteries, thereby enhancing the retrograde blood supply of the collateral circulation; a sensor module for monitoring cerebral blood flow changes in real time and uploading a monitoring result to a control module; and the control module for issuing a corresponding control instruction to the ultrasonic stimulation module according to the monitoring result uploaded by the sensor module, so as to adjust parameters of the low-frequency ultrasonic waves output by the ultrasonic stimulation module. The LIPUS technology can act directly on the scalp surface without anesthesia and surgical operations. The LIPUS technology can act directly on the peripheral terminals of trigeminal ganglion neurons around the pial arteries to dilate the local arteries; the range of action is accurate and limited, and the local blood flow velocity is directly accelerated. The functional near-infrared spectroscopy technology is further combined to monitor the cerebral blood flow changes in real time, thus improving the safety and effects of treatment.