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Oral Liquid-supplement salt quick-dissolving tablets, prepn. method therefor

A technology of rehydration salts and instant tablets, which is applied in the fields of pill delivery, active ingredients of alkali/alkaline earth metal chlorides, metabolic diseases, etc., and can solve problems such as troublesome and single way of supplementing salt

Inactive Publication Date: 2005-01-05
王玫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, people’s way of supplementing salt is still in the traditional way of injecting physiological saline in the form of medical treatment. In this way, when supplementing salt, people either go to the hospital or dissolve some salt water at home. This makes the way of supplementing salt very simple. , and very troublesome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0038] 1. Mix 1164.8g of sucrose, 154g of sorbitol, 70g of xylitol, "Tween 80 "10.5g and other auxiliary materials are mixed in the mixer, and placed in the Econo Floss machine for flash flow processing at a speed of 3600rpm, forming flocs and chopping;

[0039] 2. Mix sodium chloride 175g, sodium citrate 125g, potassium chloride 75g, anhydrous glucose 1000g, aspartame 30g, PEG 300 9g, and other ingredients are mixed, then passed through an 80-mesh sieve, and the above-mentioned flocs and other auxiliary materials are added for mixing;

[0040] 3. After determining the weight of each tablet, press it with a tablet press, and press it with a Kilian tablet press to make 1000 tablets;

[0041] 4. Dry the prepared tablet in an oven at 40 degrees centigrade and 85% KH for 15 minutes.

[0042] In this invention, while keeping the activity of the original raw materials of the product and the proportion of the ingredients unchanged, the product is made into 1000 tablets of ORS oral ...

specific Embodiment approach 2

[0043] 1. Mix 1000g of sucrose, 135g of sorbitol, 55g of xylitol, 4.5g of "Tween 80" and other auxiliary materials in the mixer, and put them in the Econo Floss machine for flash flow processing at 3600rpm to form flocs and chop them ;

[0044] 2. Mix sodium chloride 135g, sodium citrate 170g, potassium chloride 90g, anhydrous glucose 1100g, aspartame 26g, PEG 300 Mix 8g and other ingredients, then pass through an 80-mesh sieve, add the above-mentioned flocs and other auxiliary materials for mixing;

[0045] 3. After determining the weight of each tablet, press it with a tablet press, and press it with a Kilian tablet press to make 1000 tablets;

[0046] 4. Dry the prepared tablet in an oven at 40 degrees centigrade and 85% KH for 15 minutes.

[0047] In this invention, while keeping the activity of the original raw materials of the product and the proportion of the ingredients unchanged, the product is made into 1000 tablets of ORS oral rehydration salt instant Tablet dosa...

specific Embodiment approach 3

[0048] 1. Mix 1200g of sucrose, 120g of sorbitol, 55g of xylitol, 10g of "Tween 80" and other auxiliary materials in the mixer, and put them in the Econo Floss machine for flash flow processing at a speed of 3600rpm to form flocs and chop them;

[0049] 2. Mix sodium chloride 200g, sodium citrate 100g, potassium chloride 68g, anhydrous glucose 900g, aspartame 35g, PEG 300 9g and other ingredients were mixed, then passed through an 80 mesh sieve, and the above-mentioned flocs and other auxiliary materials were added for mixing.

[0050] 3. After determining the weight of each tablet, press it with a tablet press, and press it with a Kilian tablet press to make 1500 tablets;

[0051] 4. Dry the prepared tablet in an oven at 40 degrees centigrade and 85% KH for 15 minutes.

[0052] In this invention, the product is made into ORS oral rehydration salt quick-dissolving tablet dosage form by using the manufacturing method commonly used in the pharmaceutical industry to manufacture ta...

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Abstract

An orally-applied instant tablet of salt supplementing liquid CRS for supplementing salt to human body is prepared from sodium chloride, sodium citrate, potassium chloride, anhydrous glucose, cane sugar, sorbitol, tween-80, aspartame and PEG300. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to an oral fast-dissolving tablet, in particular to an oral rehydration salt fast-dissolving tablet and a preparation method thereof. Background technique: [0002] Salt is one of the indispensable ingredients in human life. According to Apalin (the world-renowned biochemist of the former Soviet Union, 1894-1980) in "The Origin of Life": "Humans and even all life are Derived and evolved from seawater, some life forms landed, while some life remained in the seawater." [0003] Originally human beings and all animals and plants on land originated from the ocean. To this day, no one disputes this theory. The sea is the mother of all life. Seawater contains a variety of minerals, and the minerals in seawater are also the minerals contained in the human body. The content of potassium and sodium ions in seawater is the highest, and potassium and sodium ions are also the main two cations in our body. They respectively preside over ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K33/14A61P3/02
Inventor 杨理林
Owner 王玫
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