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Oral liquid-supplement salt disperson tablets, and prepn. method therefor

A technology of rehydration salt and dispersion, which is applied in the directions of pill delivery, active ingredients of alkaline/alkaline earth metal chlorides, metabolic diseases, etc., can solve the problems of single and troublesome way of replenishing salt, and achieve the effect of convenient salt replenishment.

Inactive Publication Date: 2005-01-05
王玫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, people’s way of supplementing salt is still in the traditional way of injecting physiological saline in the form of medical treatment. In this way, when supplementing salt, people either go to the hospital or dissolve some salt water at home. This makes the way of supplementing salt very simple. , and very troublesome

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0030] 1. Put 1000g of pregelatinized starch and 1000g of croscarmellose sodium in the prescribed amount in an oven at 60 degrees Celsius to dry for two hours;

[0031] 2, after each main component sodium chloride 1750g, sodium citrate 1250g, potassium chloride 750g, anhydrous glucose 11000g, cross 80 mesh sieves respectively;

[0032] 3. Take half of the amount of croscarmellose sodium and mix it for 30 minutes according to the method of equal addition, then dissolve 300g of polyvinylpyrrolidone in 300g of 40% ethanol as a binder, and wet granulate with a 20-mesh sieve. drying, granulation;

[0033] 4. Mix the remaining croscarmellose sodium and magnesium stearate 200g evenly, and press the tablet directly after determining the weight of each tablet.

[0034] In this invention, while keeping the activity of the original raw materials of the product and the ratio of the ingredients unchanged, the product is made into 1,000 tablets of ORS oral rehydration salt dispersion by us...

specific Embodiment approach 2

[0035] 1. Put 1800 g of pregelatinized starch and 600 g of croscarmellose sodium in the prescribed amount in an oven at 60 degrees Celsius to dry for two hours;

[0036] 2. Finally, pass the main components of sodium chloride 1200g, sodium citrate 865g, potassium chloride 400g, and anhydrous glucose 12000g through an 80-mesh sieve;

[0037] 3. Take half the amount of croscarmellose sodium and mix it for 30 minutes according to the method of equal addition, dissolve 200g of polyvinylpyrrolidone in 30% ethanol at 250 as a binder, and wet granulate with a 20-mesh sieve. drying, granulation;

[0038] 4. Mix the remaining croscarmellose sodium and magnesium stearate 230g evenly, and press the tablet directly after determining the weight of each tablet.

[0039] In this invention, while keeping the activity of the original raw materials of the product and the ratio of the ingredients unchanged, the product is made into 1,000 tablets of ORS oral rehydration salt dispersion by using ...

specific Embodiment approach 3

[0040] 1. Put 1000g of pregelatinized starch and 1500g of croscarmellose sodium in the prescribed amount in an oven at 60 degrees Celsius to dry for two hours;

[0041] 2. After each main component sodium chloride 2200g, sodium citrate 1500g, potassium chloride 900g, anhydrous glucose 9000g, pass through 80 mesh sieves respectively;

[0042] 3. Take half of the amount of croscarmellose sodium and mix it for 30 minutes according to the method of equal addition, then dissolve 300g of polyvinylpyrrolidone in 300% ethanol as a binder, and wet granulate with a 20-mesh sieve. drying, granulation;

[0043] 4. Mix the remaining 300 g of croscarmellose sodium and magnesium stearate evenly, determine the weight of each tablet and directly compress it into tablets.

[0044] In this invention, while keeping the activity of the original raw materials of the product and the ratio of the ingredients unchanged, the product is made into 2,000 tablets of ORS oral rehydration salt dispersion by...

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Abstract

An orally-applied dispersing tablet for supplementing salt to human body is prepared from sodium chloride, sodium citrate, potassium chloride, anhydrous glucose, dicarbonate, pregelatinized starch, polyvinyl pyrrolidone, meganesium stearate, and cross-linking carboxymethyl cellulose sodium. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to an oral dispersible tablet, in particular to an oral rehydration salt dispersible tablet and a preparation method thereof. Background technique: [0002] Salt is one of the indispensable ingredients in human life. According to Apalin (the world-renowned former Soviet biochemist, 1894-1980) in "(The Origin of Life") said: "Humans and even all life are It is derived and evolved from seawater, some life forms landed, and some life forms still live in seawater." [0003] Originally human beings and all animals and plants on land originated from the ocean. To this day, no one disputes this theory. The sea is the mother of all life. Seawater contains a variety of minerals, and the minerals in seawater are also the minerals contained in the human body. The content of potassium and sodium ions in seawater is the highest, and potassium and sodium ions are also the main two cations in our body. They respectively preside over the wo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K33/14A61P3/02
Inventor 杨理林
Owner 王玫
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