Dripping pills of corydalis tuber and its preparation process

The technology of Suo dropping pills and Corydalis Corydalis, which is applied in the field of Corydalis Corydalis Dropping Pills and its preparation, can solve the problems of unfavorable improvement of patients' ability to seek medical treatment, low dissolution rate and high production cost, and achieves improved bioavailability, accelerated dissolution and absorption, increased The effect of stability

Active Publication Date: 2006-02-08
COSCI MED TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicines, have long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. problems, thus affecting the efficacy of the drug, and directly affecting the therapeutic effect
In addition, conventional traditional Chinese medicine oral dosage forms, such as traditional pills, powders, ointments, pills, etc., have low drug content, large dosage, and poor taste, while tablets, capsules, granules (infusions), etc. have The granulation process, therefore, will produce relatively large dust pollution, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of the Corydalis Corydalis Dropping Pills of the present invention is further described.

[0030] [recipe selection]

[0031] 1. Raw materials: According to the method provided in [Preparation Method 1], the dry powder of the drug extract containing the active ingredient of the traditional Chinese medicine Corydalis Corydalis is pre-prepared for use;

[0032] 2. Single matrix: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0033] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combination test;

[0034] 3.1 The combination of two different su...

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PUM

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Abstract

The invention discloses a medicinal composition for treating coronary disease, angina pectoris and myocardiac infarction, especially a dripping pill of corydalis tuber and its preparation process, wherein the dripping pill is prepared from corydalis tuber, and medicinal carrying agent as the base material.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the function of promoting blood circulation and removing blood stasis, benefiting qi and relieving pain, and is used for the treatment of coronary heart disease, angina pectoris, acute myocardial infarction, old myocardial infarction, chest tightness, suffocation, palpitation and dizziness, etc. An oral preparation prepared from raw materials. Background technique [0002] According to the ministerial drug standard WS 3 - Kedaling Tablets prepared by the preparation method given in B-3167-98, is a kind of blood circulation promoting blood stasis, promoting Qi and analgesic effect, used for coronary heart disease, angina pectoris, acute myocardial infarction, old myocardial infarction Oral tablets for the treatment of chest tightness, shortness of breath, palpitations, and vertigo have been clinically verified for many years and have definite curative effects. They are commonly us...

Claims

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Application Information

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IPC IPC(8): A61K36/50A61K9/20A61P9/10
Inventor 王锦刚
Owner COSCI MED TECH CO LTD
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