Production of disposable electrochemical biological sensor

The technology of a biosensor and a manufacturing method is applied in the manufacturing field of a one-time-use electrochemical biosensor, which can solve the problems of limitation, electrode stability, poor consistency, and high production cost, so as to reduce inaccurate measurement results and be easy to use. Effect

Inactive Publication Date: 2006-05-31
INST OF ELECTRONICS CHINESE ACAD OF SCI
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  • Abstract
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Problems solved by technology

However, the production cost of photolithography is high; the electrodes obtained by screen printing have problems such as stability and poor consistency.
In Korean Patent No. 00807084.9, an electrode method for manufacturing an electrochemical biosensor test strip is mentioned. It forms two electrodes parallel to each other in the length direction on a grooved insulating substrate by a splash method, but its precondition is to ensure The mask used is in close contact with the insulating substrate. Otherwise, when the metal material is splashed, because the metal material penetrates into the gap, it is easy to form a stacked electrode pattern, and in this insulating substrate with a groove The formation of other electrode patterns on the chip will be limited, such as multi-parameter integrated electrodes

Method used

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  • Production of disposable electrochemical biological sensor
  • Production of disposable electrochemical biological sensor
  • Production of disposable electrochemical biological sensor

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Embodiment Construction

[0038] The preferred embodiments of the present invention can be well understood with reference to the drawings. In the drawings, the same reference numerals respectively indicate the same and corresponding parts. The preferred embodiment uses a two-electrode biosensor, which is only used to illustrate the purpose of the present invention, not to limit the present invention.

[0039] Fig. 1 is a perspective view schematically showing the structure of a disposable electrochemical biosensor according to the present invention. It can be seen from the figure that the disposable electrochemical biosensor of the present invention includes an insulating substrate 1 on which an electrode system 2 is formed using micro-electromechanical processing technology, and a double-sided tape is attached to the electrode system 2 The insulating layer 3 of glue, which forms the capillary channel 4 with the insulating substrate 1 ( Figure 1A ). Then a reaction reagent 5 is fixed on the capillary chan...

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Abstract

A method for preparing a disposable electrochemical biological transducer includes forming required electrode on insulation base material by utilizing micro mechanical processing technique, binding insulation layer on said base material to prepare electrode channel then fixing reaction reagent in capillary channel space, finally packaging them to form a disposable electrochemical biological transducer.

Description

Technical field [0001] The invention relates to the technical field of sensors, and is a manufacturing method of a disposable electrochemical biosensor for detecting certain analytes (such as biological substances in human blood). Background technique [0002] In recent years, electrochemical biosensors have been widely used in clinical medicine, environmental monitoring, and pharmaceutical industries due to their accurate, rapid and easy quantitative determination of biological substances contained in liquid samples such as whole blood, serum, plasma, urine, etc. And other fields. At present, there are many commercial electrochemical biosensors, such as glucose sensors and lactate sensors. [0003] Electrode methods are widely used for the production of electrochemical biosensors. As mentioned in US Patent No. 5437999, a method of using photolithography to pattern a conductive material fixed on an insulating substrate; and a method of directly printing the conductive material on...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327G01N33/50H05K3/16H05K3/22
Inventor 姜利英蔡新霞李华清罗贤波刘春秀王慧郭宗慧周爱玉
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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