Porcine pancreatic islet cultured with porcine sertoli cells for xenotransplantation

A technology to support cells and islets, applied in the field of diabetes treatment
CN1791670AInactive Publication Date: 2006-06-21戴伯塞尔有限公司
1 Cites 3 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
戴伯塞尔有限公司
Publication Date
2006-06-21
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Aggregates and their method of preparation suitable for implantation into a recipient in order to produce insulin in vivo. The methods involve culturing islet cells isolated from the pancreas of donor piglets with isolated Sertol i cells from the testes of donor piglets. A preferred period of culturing is 5 days and may be followed by a purification procedure.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the use of porcine pancreatic islet cells for treating diabetes. More particularly but not exclusively, the present invention relates to the use of porcine pancreatic islet cells together with Sertoli cells for treating diabetes by xenotransplantation. Background technique

[0002] Background and rationale of porcine islet cell xenotransplantation

[0003] Type 1 (insulin-dependent) diabetes mellitus is a common endocrine disorder that causes considerable morbidity and mortality and has serious economic implications for individual patients and healthcare systems. Although life-saving, treatment with insulin often does not provide sufficient control of blood glucose to prevent life-shortening complications of the disease, prompting extensive research on better ways to achieve and maintain normoglycemia . Among the newer therapeutic strategies proposed, transplantation of pancreatic beta islet cells obtained from human beings ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More