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Liver tonic and novel preparation method thereof

A technology for preparations and traditional Chinese medicine preparations, which can be used in anti-inflammatory agents, pill delivery, pharmaceutical formulations, etc., and can solve the problems of many impurities, affecting clinical applications, and large doses.

Inactive Publication Date: 2006-12-20
FUKANGREN BIO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in practice, because the medicine is prepared by powdering the medicinal materials into the medicine, there are many impurities and large doses, which seriously affect its clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] The preparation method of dropping pill of the present invention:

[0063] prescription:

[0064] Angelica 144g Chuanxiong 72g Paeoniae Alba 96g

[0065] Rehmannia glutinosa 144g Fangfeng 72g Notopterygium 72g

[0066] PEG4000 100g

[0067] Makes 1000 pills

[0068] Preparation:

[0069] (1) Radix Paeoniae Alba and Radix Rehmanniae were extracted twice with ethanol under reflux, the amount of ethanol solvent was 6 times that of medicinal materials, the concentration of ethanol was 80%, and the reflux time was 1.5 hours. The ethanol extract was concentrated under reduced pressure to obtain the ethanol extract;

[0070] (2) Extract the volatile oil from Angelica, Rhizoma Chuanxiong, Fangfeng and Notopterygium, add water to distill, add 8 times the amount of water, and extract for 6 hours to obtain the extracted volatile oil;

[0071] (3) Add water to extract the medicinal residues after the above ethanol extraction and extract the volatile oil twice, the amount of w...

Embodiment 2

[0074] The preparation method of soft capsule of the present invention:

[0075] prescription:

[0076] Angelica 760g Chuanxiong 360g Paeoniae Alba 480g

[0077] Rehmannia glutinosa 760g Fangfeng 360g Notopterygium 360g

[0078] PEG400500g

[0079] Makes 1000 capsules

[0080] Preparation:

[0081] (1) Radix Paeoniae Alba and Radix Rehmanniae were extracted twice with ethanol under reflux, the amount of ethanol solvent was 6 times that of medicinal materials, the concentration of ethanol was 80%, and the reflux time was 1.5 hours. The ethanol extract was concentrated under reduced pressure to obtain the ethanol extract;

[0082] (2) Extract the volatile oil from Angelica, Rhizoma Chuanxiong, Fangfeng and Notopterygium, add water to distill, add 8 times the amount of water, and extract for 6 hours to obtain the extracted volatile oil;

[0083] (3) Add water to extract the medicinal residues after the above ethanol extraction and extract the volatile oil twice, the amount ...

Embodiment 3

[0086] The preparation method of granule of the present invention:

[0087] prescription:

[0088] Angelica 360g Chuanxiong 180g Paeoniae Alba 240g

[0089] Rehmannia glutinosa 360g Fangfeng 180g Notopterygium 180g

[0090] Made into 1000g

[0091] Preparation:

[0092] (1) Take Radix Paeoniae Alba and Rehmannia glutinosa and grind them into fine powder, set aside;

[0093] (2) Extract the volatile oil from Angelica, Rhizoma Chuanxiong, Fangfeng and Notopterygium, add water to distill, add 8 times the amount of water, and extract for 6 hours to obtain the extracted volatile oil;

[0094] (3) Add water to extract the medicinal dregs after the above volatile oil is extracted twice, the amount of water added is 6 times, and the extraction time is 1.5 hours each time, the extracts are combined, filtered, and the filtrate is concentrated under reduced pressure to a relative density of 1.18~1.22 (50 ℃ test) clear paste, let it cool, add ethanol to make the alcohol content reach...

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PUM

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Abstract

The invention relates to a Chinese medicinal composition and preparing process thereof, wherein the composition can be used for treating vertigo, hypochondriac pain, cephalalgia, and limb pain. The preferred dosage forms include drop pill and soft capsule.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation process thereof, in particular to a prescription and a preparation process thereof for head dizziness, hypochondriac pain, headache and limb pain caused by liver blood deficiency and wind-evil. Background technique: [0002] Head dizziness, hypochondriac pain, headache, and limb pain caused by liver blood deficiency and wind evil are common clinical symptoms. Traditional Chinese medicine often adopts the method of nourishing blood and dispelling wind to treat them, and the curative effect is remarkable. Bugan Wan is its representative drug. However, in practice, because the medicine is prepared by powdering the medicinal materials, it leads to many impurities and large doses, which seriously affects its clinical application. [0003] Compared with ordinary pills, the preparation prepared by the extraction process of the present invention can better collect the essen...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/00A61K9/06A61K9/14A61K9/16A61K9/20A61K9/48A61P25/04A61P29/00
Inventor 刘露
Owner FUKANGREN BIO PHARMA