High efficiency and low toxicity externally applied medicine preparation of ginsenoside and triamcinolone acetonide

A technology of ginsenoside and triamcinolone, which is applied in the directions of medical preparations containing active ingredients, drug delivery, drug combination, etc., can solve the problems of side effects, difficulties in clinical external use of glucocorticoids, etc.

Inactive Publication Date: 2007-06-27
GUANGDONG MEDICAL UNIV
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Problems solved by technology

This brings difficulties to the clinical application of glucocorticoids
Inappro...

Method used

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Embodiment 1

[0011] In order to observe the skin histopathological characteristics, skin-related biochemical indicators and changes in immune organs of mice with skin atrophy induced by external application of triamcinolone; at the same time, to observe the effect of compound ginsenoside triamcinolone paint on skin adverse reactions to glucocorticoids preventive effect, we carried out the following

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Abstract

The present invention is externally applied medicine composition comprising glucocorticoid hormone and ginsenoside and with high curative effect and less side effect. Glucocorticoid hormone is important medicine for treating dermatosis but has some serious untoward reactions. It is found that the composition of ginsenoside and triamcinolone acetonide as one glucocorticoid hormone has strengthened anti-inflammatory action and less untoward reactions, and may be used in treating various kinds of dermatosis.

Description

technical field [0001] Glucocorticoids for external use are commonly used medicines for clinical treatment of skin diseases, but these external medicines all have relatively large side effects. The invention relates to a group of external glucocorticoid agents composed of ginsenoside and triamcinolone with high curative effect and few side effects. Background technique [0002] Since the 1950s, the topical application of glucocorticoids has achieved good results in the treatment of some skin diseases. However, since the 1970s, due to improper external use and abuse, local side effects, especially skin atrophy, have gradually increased. This brings difficulties to the clinical application of glucocorticoids. Inappropriate use of glucocorticoids can lead to a series of skin and systemic side effects. Skin manifestations may include: skin atrophy, atrophic lines, telangiectasia, pigmentation, etc. Systemic side effects may include: muscle atrophy, osteoporosis, aseptic join...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61K36/258A61K9/00A61P17/00A61K31/58A61K31/573
Inventor 吴铁崔燎陈志东许宗严高敏坚高志祥
Owner GUANGDONG MEDICAL UNIV
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