Cell analysis in multi-through-hole testing plate

a multi-through-hole, cell technology, applied in the field of multi-through-hole testing plates, can solve the problems of increased overall cost of testing procedures, difficult filling of wells in these testing apparatuses, and difficulty in special delivery systems, etc., to simplify testing procedures, simplify the construction of testing apparatuses, and facilitate identification
US20050059074A1Inactive Publication Date: 2005-03-17LIFE TECH CORP
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Patent Information

Authority / Receiving Office
US ยท United States
Patent Type
Applications(United States)
Current Assignee / Owner
LIFE TECH CORP
Publication Date
2005-03-17
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

A spatially fixed library of mutated cells and a method for creating such a library. The library is created by creating a set of cells having a genetic diversity, causing the cells to multiply and express phenotypes, preparing a solution containing the cells diluted in a medium, populating a plurality of through-holes of a testing plate with the solution such that surface tension holds the solution in respective through-holes, and analyzing the phenotypes of the cells in the solution on a hole-by-hole basis. Cells expressing specified phenotypes may then be retrieved.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a divisional application of copending Ser. No. 10 / 223,893, filed Aug. 20, 2002, which is a continuation of U.S. Ser. No. 09 / 970,578 (issued as U.S. Pat. No. 6,436,632), which is a continuation of U.S. Ser. No. 09 / 528,085 (issued as U.S. Pat. No. 6,306,578), which is a continuation-in-part of U.S. Ser. No. 09 / 471,852 (abandoned), which is a continuation of U.S. Ser. No. 09 / 272,122 (issued as U.S. Pat. No. 6,027,873). Each of the patent applications described in this paragraph is hereby incorporated herein by reference.FIELD OF THE INVENTION

[0002] This invention is related generally to a testing apparatus and, more particulary, to a multi-through hole testing plate for high throughout screening. BACKGROUND OF THE INVENTION

[0003] Prior testing apparatuses have consisted of a testing plate with a pair of opposing surfaces and plurality of wells. The wells extend in from one of the opposing surfaces, but do not extend t...

Claims

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