Controlled, non-linear focused ultrasound treatment

Inactive Publication Date: 2007-01-18
INSIGHTEC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0004] In accordance with one embodiment of the invention, a method of treating tissue within a body includes delivering a first level of ultrasound energy to a target tissue region for a first duration resulting in the generation of microbubbles in the target tissue region, determining one or more characteristics of the targe

Problems solved by technology

In this process, the ultrasonic energy is “absorbed” by the tissue, causing the generation of heat.
On the other hand, the reaction of tissue containing a higher relative percentage of microbubbles to the con

Method used

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  • Controlled, non-linear focused ultrasound treatment
  • Controlled, non-linear focused ultrasound treatment
  • Controlled, non-linear focused ultrasound treatment

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Embodiment Construction

[0018]FIG. 1A illustrates a focused ultrasound system 10 in accordance with some embodiments. The system 10 includes an ultrasound transducer 14, drive circuitry (driver) 16 coupled to the transducer 14, a controller 18 coupled to the driver 16, an imaging device 20, and a processor 22 coupled to the imaging device 20 and the controller 18. The transducer 14 may direct acoustic energy represented by beam 15 towards a target 42, typically a tumor or other tissue region, within a patient 40. The beam 15 may be used to coagulate, generate mechanical damage, necrose, heat, or otherwise treat the target 42, which may be a benign or malignant tumor within an organ or other tissue structure (not shown). The system 10 also includes a user interface (UI) 23, such as a screen, keyboard, a mouse, a button, a touch pad, and the like, for allowing a user to input data, such as treatment parameters, to the processor 22. The user interface 23 is shown as a separate component from the processor 22....

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Abstract

A system for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region for a first duration resulting in the generation of microbubbles in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the microbubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

Description

FIELD OF INVENTION [0001] The present invention relates generally to apparatus and methods for delivering focused ultrasound energy to targeted tissue regions in a patient's body. BACKGROUND [0002] High intensity focused ultrasonic energy (i.e., having a frequency greater than about 20 kilohertz), may be used therapeutically to treat internal tissue regions within a patient. For example, ultrasonic waves may be used to induce coagulation and / or necrosis in a target tissue region, such as a tumor. In this process, the ultrasonic energy is “absorbed” by the tissue, causing the generation of heat. The absorbed energy heats the tissue cells in the target region to temperatures that exceed protein denaturation thresholds, usually above 60° C., resulting in coagulation and / or necrosis of the tissue in the target region. [0003] During a focused ultrasound procedure, small gas bubbles, or “microbubbles,” may be generated in the liquid contained in the tissue, e.g., due to the stress resulti...

Claims

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Application Information

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IPC IPC(8): A61B8/00
CPCA61B8/467A61B8/481A61B19/5225A61N7/02A61B2019/5236A61B2019/5238A61B2019/5276A61B2017/22008A61B90/37A61B2090/374A61B2090/376A61B2090/378
Inventor VORTMAN, KOBIVITEK, SHUKIFREUNDLICH, DAVID
Owner INSIGHTEC
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