Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Controlled, non-linear focused ultrasound treatment

Inactive Publication Date: 2007-01-18
INSIGHTEC
View PDF100 Cites 193 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0004] In accordance with one embodiment of the invention, a method of treating tissue within a body includes delivering a first level of ultrasound energy to a target tissue region for a first duration resulting in the generation of microbubbles in the target tissue region, determining one or more characteristics of the targe

Problems solved by technology

In this process, the ultrasonic energy is “absorbed” by the tissue, causing the generation of heat.
On the other hand, the reaction of tissue containing a higher relative percentage of microbubbles to the continued application of the ultrasound energy is non-linear and difficult to predict.
This mechanism, called “cavitation,” may cause extensive tissue damage beyond that targeted, and may be difficult to control.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Controlled, non-linear focused ultrasound treatment
  • Controlled, non-linear focused ultrasound treatment
  • Controlled, non-linear focused ultrasound treatment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018]FIG. 1A illustrates a focused ultrasound system 10 in accordance with some embodiments. The system 10 includes an ultrasound transducer 14, drive circuitry (driver) 16 coupled to the transducer 14, a controller 18 coupled to the driver 16, an imaging device 20, and a processor 22 coupled to the imaging device 20 and the controller 18. The transducer 14 may direct acoustic energy represented by beam 15 towards a target 42, typically a tumor or other tissue region, within a patient 40. The beam 15 may be used to coagulate, generate mechanical damage, necrose, heat, or otherwise treat the target 42, which may be a benign or malignant tumor within an organ or other tissue structure (not shown). The system 10 also includes a user interface (UI) 23, such as a screen, keyboard, a mouse, a button, a touch pad, and the like, for allowing a user to input data, such as treatment parameters, to the processor 22. The user interface 23 is shown as a separate component from the processor 22....

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A system for treating tissue within a body is configured to deliver a first level of ultrasound energy to a target tissue region for a first duration resulting in the generation of microbubbles in the target tissue region, determine one or more characteristics of the target tissue region in the presence of the microbubbles, and deliver a second level of ultrasound energy to the target tissue region for a second duration, wherein one or both of the second energy level and the second duration are based, at least in part, on the determined one or more characteristics of the target tissue region.

Description

FIELD OF INVENTION [0001] The present invention relates generally to apparatus and methods for delivering focused ultrasound energy to targeted tissue regions in a patient's body. BACKGROUND [0002] High intensity focused ultrasonic energy (i.e., having a frequency greater than about 20 kilohertz), may be used therapeutically to treat internal tissue regions within a patient. For example, ultrasonic waves may be used to induce coagulation and / or necrosis in a target tissue region, such as a tumor. In this process, the ultrasonic energy is “absorbed” by the tissue, causing the generation of heat. The absorbed energy heats the tissue cells in the target region to temperatures that exceed protein denaturation thresholds, usually above 60° C., resulting in coagulation and / or necrosis of the tissue in the target region. [0003] During a focused ultrasound procedure, small gas bubbles, or “microbubbles,” may be generated in the liquid contained in the tissue, e.g., due to the stress resulti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61B8/00
CPCA61B8/467A61B8/481A61B19/5225A61N7/02A61B2019/5236A61B2019/5238A61B2019/5276A61B2017/22008A61B90/37A61B2090/374A61B2090/376A61B2090/378
Inventor VORTMAN, KOBIVITEK, SHUKIFREUNDLICH, DAVID
Owner INSIGHTEC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com