30 results about "Contrast enhance ultrasound" patented technology

Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.

Methods for contrast-enhanced ultrasound imaging that implement coded multi-pulses in each of two or more different transmission events are described. Data acquired in response to the two different transmission events are decoded and combined. In some embodiments, the coded multi-pulses include two or more consecutive Hadamard encoded ultrasound pulses. In other embodiments, multiplane wave pulsescan be used. Such multiplane wave pulses can be coded using Hadamard encoding, as one example. In addition, the multiplane wave pulses can be further coded using amplitude modulation, pulse inversion, or pulse inversion amplitude modulation techniques.

The present invention relates to an ultrasound imaging system (10) for inspecting an object (97) in a volume (40). The ultrasound imaging system comprises an image processor (36) configured to conduct a segmentation (80) of the object (97) simultaneously out of three-dimensional ultrasound mage data (62) and contrast-enhanced three-dimensional ultrasound image data (60). In particular, this may be done by minimizing an energy tem taking into account both the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data. By this, the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data may even be registered during segmentation. Hence, this invention allows a more precise quantification of one organ in two different modalities as well as the registration of two images for simultaneous visualization.

Systems and methods using contrast enhanced ultrasound imaging for quantitative assessment of neovascularization, such as within a tumor or a plaque. The contrast agent moves in small blotches rather than in continuous flow, but image processing methods enable the detection and quantification of the blood flow, even in the tiny blood vessels of the vasculature tree. The image processing includes compensation for motion of the tissue arising from body movement. The position and extent of the discrete positions of contrast material may be accumulating during a complete heart cycle onto a single 2D image, to enable an indication of a vascular tree based on this local accumulated image. Dynamic processing (DP) of the discrete positions of contrast material enables a complete vascular tree to be obtained. The neovascularization is quantified by the ratio of its total area to that of the plaque in which the neovascularization has grown.

Provided are an ultrasound diagnosis apparatus and method for analyzing a contrast enhanced ultrasound image. The ultrasound diagnosis apparatus and method determine, by analysis, causes of defects in a frame of an ultrasound image based on a time intensity curve and allow visual display of the defective frame based on the determined causes. Furthermore, the ultrasound diagnosis method and apparatus may provide a user interface for quick access to causes of defects in a frame of the ultrasound image and to a position of the defective frame.

An ultrasonic diagnostic imaging system and method acquire a sequence of image data as a bolus of contrast agent washes into and out of the liver. The image data of contrast intensity is used to compute time-intensity curves of contrast flow for points in an ultrasound image. Time-dependent data is calculated from the data of the time-intensity curves which, in a described implementation, comprise first and second derivatives of the time-intensity curves. A color map is formed of the time-dependent data or the polarities of the data and displayed in a parametric image as a color overlay of a contrast image of the liver.

The invention relates to the field of biomedical materials, in particular to a preparation with ultrasound contrast and photothermal therapy properties, a preparation method and application thereof. Firstly, hollow SiO2 spheres are prepared by the template method, and then surface seeding and chemical reduction methods are used to coat gold nanoshells on the surface, and finally, moisture is removed by vacuum freeze-drying, and gas is filled to obtain an integrated photothermal diagnosis and treatment guided by ultrasound images. chemicals. The hollow SiO2 sphere containing gas has a good response to ultrasound for clinical diagnosis, and the gold nanoshell coated with the outer layer can convert the light energy of the absorbed near-infrared laser into heat energy, which is used to kill malignant tumor cells. The invention combines ultrasonic diagnosis and photothermal therapy preparations into one, locks the lesion through ultrasound contrast-enhanced examination, and then applies laser irradiation to carry out photothermal therapy under the guidance of ultrasonic images, which reduces the pain of patients and improves the treatment efficiency. efficiency.

The invention discloses a method for extracting a blood vessel perfusion region from contrast-enhanced ultrasound images based on a brox optical flow method. The method comprises the steps of (1) obtaining image frames and forming a contrast-enhanced ultrasound image sequence, (2) conducting image preprocessing to reduce speckle noise of each contrast-enhanced ultrasound image, (3) estimating a motion field of every two frames of adjacent contrast-enhanced ultrasound images based on the brox optical flow method, and correcting the two frames of adjacent contrast-enhanced ultrasound images according to an estimated deviation value, and (4) extracting points of the blood vessel perfusion region through a threshold segmentation method. The method has the advantages that the brox optical flow method which is insensitive to noise and high in robustness is adopted to estimate motion displacement of the adjacent image frames and correct the motion displacement; based on the corrected contrast-enhanced ultrasound image sequence, the perfusion region is extracted different from signal features of other tissue backgrounds according to highlight and flashing expressed by radiography microbubbles in blood; experiment results show that the method is small in calculated quantity, easy to realize and good in extraction effect when applied to clinical data.

The present invention relates to a method for quantifying drug delivery with the characteristic of measuring the signal intensity of peripheral vessels with a contrast-enhanced ultrasound to quantify the drug delivery at a target site. The present invention can be used for quantifying UTMD (ultrasound triggered microbubble destruction) targeted drug delivery, also for qualifying the unreleased amount of the long-acting drug in the tested object, and for helping setting the treatment schedule for ultrasound disruption of blood-brain barrier.

An ultrasound system and method are described for acquiring a sequence of ultrasound images of a carotid artery during delivery of a contrast agent. Plaques in the image shown are identified and time-intensity curves are calculated for pixels in the image. Intensity values ​​before and after arrival of the contrast agent are compared to identify pixels or groups of pixels with perfusion. An anatomical image can be created showing the intensity of perfusion and the area of ​​the image of the plaque present, or the perfusion can be quantified by determining the percentage of pixels in the plaque exhibiting perfusion. The extent and degree of perfusion is an indicator of the risk of plaque particles in the bloodstream that may cause stroke-related symptoms.