Abuse-proofed dosage form

a dosage form and dosage technology, applied in the field of abuse-proofed dosage forms, can solve the problems of preventing subsequent abuse, pulverizing the dosage form considerably more difficult using conventional means, and preventing the subsequent abuse, so as to prevent parenteral, nasal and/or oral abus
US20070048228A1Inactive Publication Date: 2007-03-01GRUNENTHAL GMBH
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
GRUNENTHAL GMBH
Publication Date
2007-03-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a dosage form that is thermoformed without discoloration and is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking strength of at least 500 N in addition to one or more active substances that could be subject to abuse. The invention also relates to a corresponding method for producing said dosage form.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a Continuation-in-Part-Application of pending U.S. patent application Ser. No. 11 / 349,544 filed on Feb. 6, 2006, a Continuation-in-Part-Application of pending U.S. patent application Ser. No. 11 / 348,295 filed on Feb. 6, 2006, a Continuation-in-Part-Application of pending U.S. patent application Ser. No. 10 / 718,112 filed on Nov. 20, 2003 and claims priority of German Patent Application No. 10 2005 005446.3 filed on Feb. 4, 2005 and German Patent Application No. 10 336 400.5 filed on Aug. 6, 2003.BACKGROUND OF THE INVENTION

[0002] The present invention relates to an abuse-proofed dosage form thermoformed by extrusion without discoloration and containing, in addition to one or more active ingredients with abuse potential (A) optionally together with physiologically acceptable auxiliary substances (B), at least one synthetic or natural polymer (C) and optionally at least one wax (D), wherein the dosage form exhibits a br...

Claims

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