Methods and materials for controlling the electrochemistry of analyte sensors

a technology of electrochemistry and sensors, applied in the field of devices and methods for controlling the electrochemistry of analyte sensors, can solve the problems of lowering blood pressure, reproducibility, speed of response, and/or the detection range,

Inactive Publication Date: 2007-10-04
MEDTRONIC MIMIMED INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0010]Embodiments of the invention disclosed herein include electrochemical analyte sensors comprising elements such as electrodes and/or electrode combinations (e.g. working and counter electrode combinations) designed to optimize factors including the reactivity, sensitivity, functioning and lifespan of the analyte sensors. An illustrative embodiment of the invention is a method of performing an electrochemical reaction within an analyte sensor comprising using an analyte sensor constructed to include an electrode layer configuration that is designed to optimize the electrochemical reaction at the electrode when the electrode is exposed to an analyte. In such methods the analyte sensor typically includes at least one electrode disposed upon a base substrate where this base substrate comprises a geometric feature selected to increase the surface area of an electrochemically reactive surface o

Problems solved by technology

A concentration of glucose below the normal range, or hypoglycemia, can cause unconsciousness and lowered blood pressure, and may even result in death.
While numerous devices for determination of g

Method used

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  • Methods and materials for controlling the electrochemistry of analyte sensors
  • Methods and materials for controlling the electrochemistry of analyte sensors
  • Methods and materials for controlling the electrochemistry of analyte sensors

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Embodiment Construction

[0021]Unless otherwise defined, all terms of art, notations and other scientific terms or terminology used herein are intended to have the meanings commonly understood by those of skill in the art to which this invention pertains. In some cases, terms with commonly understood meanings are defined herein for clarity and / or for ready reference, and the inclusion of such definitions herein should not necessarily be construed to represent a substantial difference over what is generally understood in the art. Many of the techniques and procedures described or referenced herein are well understood and commonly employed using conventional methodology by those skilled in the art. As appropriate, procedures involving the use of commercially available kits and reagents are generally carried out in accordance with manufacturer defined protocols and / or parameters unless otherwise noted. A number of terms are defined below.

[0022]The term “analyte” as used herein is a broad term and is used in it...

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Abstract

Embodiments of the invention provide electrochemical analyte sensors having elements designed to modulate their electrochemical reactions as well as methods for making and using such sensors.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is related to U.S. patent application Ser. No. 10 / 273,767 filed Oct. 18, 2002 (published as US-2004-0074785-A1), U.S. patent application Ser. No. 10 / 861,837, filed Jun. 4, 2004 and U.S. patent application Ser. No. 11 / 301,512, filed Dec. 13, 2005, the contents of each of which are incorporated herein by reference.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]This invention relates to devices and methods for controlling the electrochemistry of analyte sensors such as glucose sensors used in the management of diabetes.[0004]2. Description of Related Art[0005]Electrochemical measurements are widely used to determine the concentration of specific substances in fluids including biological analytes such as glucose and lactate. Maintaining the appropriate concentrations of glucose in the blood of an individual for example is extremely important for maintaining homeostasis. A concentration of glucose below the no...

Claims

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Application Information

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IPC IPC(8): C12Q1/00G01N33/487
CPCA61B5/1486G01N27/307G01N27/327Y10T428/12479Y10T428/12389Y10T428/12889Y10T428/12875Y10T428/12493C25D1/10C25D5/10C25D5/623C25D5/605C25D5/611
Inventor SHAH, RAJIVHOSS, UDOGOTTLIEB, REBECCA K.SOUNDARARAJAN, GOPIKRISHNANHOLKER, JAMES D.
Owner MEDTRONIC MIMIMED INC
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