Acetamide derivative having defined particle size
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FIG. 1 is a graph depicting particle size distributions for six lots of modafinil: Lots L-1, L-2, E-A, E-B, E-C and E-D.
FIG. 2 is a scanning electron micrograph of a sample of modafinil Lot E-D at 50.times. magnification.
FIG. 3 is a scanning electron micrograph of a sample of modafinil Lot E-D at 100.times. magnification.
FIG. 4 is a scanning electron micrograph of a sample of modafinil Lot L-1 at 50.times. magnification.
FIG. 5 is a scanning electron micrograph of a sample of modafinil Lot L-1 at 100.times. magnification.
FIG. 6 is a graph depicting the dissolution rate of modafinil particles from Lot E-D (median particle size 94.05 .mu.m) and Lot L-1 (median particle size 50.18 .mu.m).
FIG. 7 is a graph depicting the dissolution rate of modafinil particles from Lot E-B (median particle size 89.10 .mu.m), Lot E-D (median particle size 94.05 .mu.m) and Lot L-1 (median particle size 50.18 .mu.m).
FIG. 8 is a graph depicting mean plasma con...
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