The present application belongs to the field of chemical purification, and particularly relates to a method for removing residual solvents in
fluorescein sodium, and more particularly, the present application provides a method for removing residual solvents in
fluorescein sodium by adding water to the
fluorescein sodium containing residual solvents or using
moisture in the environment to replace the residual solvents in the
fluorescein sodium, and then
drying the
fluorescein sodium to remove water. The method provided by the present application is simple to operate, easy to realize industrialization, low in cost, green and
environmentally friendly, convenient for
quality control in the process of
drug preparation, and meets the requirements in regulations.