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Miniature fluid temperature controlling device and method thereof

A temperature control device and microfluidic technology, which are applied in temperature control, temperature control by electric means, non-electric variable control, etc., can solve the problems of time course affecting temperature control, slowing down of the heating rate of PCR chip 100, etc. To achieve the effect of speeding up the temperature control time course

Inactive Publication Date: 2009-07-15
IND TECH RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the radiator 110 is fixed on the PCR chip 100, the speed of heating up the PCR chip 100 is slowed down, which affects the time course of the entire temperature control.

Method used

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  • Miniature fluid temperature controlling device and method thereof
  • Miniature fluid temperature controlling device and method thereof
  • Miniature fluid temperature controlling device and method thereof

Examples

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Embodiment Construction

[0036] figure 2 It is a simplified schematic diagram of a microfluidic temperature control device in a preferred embodiment of the present invention. Please refer to figure 2 The chip 200 of the microfluidic temperature control device can cooperate with the automatic control of the computer 210 to construct an automatic temperature control system. The computer 210 has automatic process control hardware or software, which can start or close the heater 220 according to the set temperature conditions to heat the microfluid in the chip 200 to a predetermined temperature, and the microfluid is only tens of microliters, so Heating is extremely easy. In addition, the computer 210 can also receive the signal output by the temperature sensor 230 to feed back the temperature of the control chip 200 . In addition, the chip 200 of the microfluidic temperature control device can cooperate with the voltage modulation signal provided by the power supply 240 to drive the actuator 250 bac...

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PUM

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Abstract

The invention relates to micro fluid temperature control device. It include chip, support structure, heat conducting block, and actuator. The chip has reaction chamber used to set micro fluid heated to required reaction temperature by the chip. In cooling operation time, the heat conducing block can contact the chip under the pushing of the actuator to remove heat on the chip by heat conduction type and realize fast cooling. In addition, in heating up operation time, the heat conducing block doesn't contact the chip to make the micro fluid fast heat up to reach the required reaction temperature.

Description

technical field [0001] The invention relates to a temperature control device, and in particular to a microfluid temperature control device and a method thereof. Background technique [0002] Polymerase chain reaction (Polymerase Chain Reaction, referred to as PCR) is to use a small amount of deoxyribonucleic acid (referred to as DNA) polymerase to carry out a specific chain reaction in a chip or a test tube, so that a section of gene is copied into the original 100 100 million to 100 billion times, in order to facilitate the rapid detection of specific pathogenic nucleic acids or disease genes. The gene of DNA is a double helix structure, and when DNA is replicating, the complementary strands of the two double helices bonded by hydrogen bonds must be separated before they can be copied as individual single helices, and the easiest way to open the DNA double helix is ​​to heat. At high temperature, the double-stranded DNA will separate into single strands, and when the tempe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G05D23/19G05D23/24C12P19/34
Inventor 黄建志王美雅柳文滨
Owner IND TECH RES INST
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