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34 results about "Dna double helix" patented technology

Water-soluble perylene bisimide compound and application of water-soluble perylene bisimide compound serving as DNA intercalator in anticancer cells and tumors

The invention discloses a water-soluble perylene bisimide compound and an application of a water-soluble perylene bisimide compound for preparing DNA intercalators, inhibiting cancer cell growth and resisting tumors, belonging to the technical field of biological drug chemical synthesis. A cationic amino functional group is introduced into perylene derivatives and single perylene systems, so that the water solubility is greatly improved, the amino functional group is bound to light stability of perylene derivatives, and a series of novel water-soluble perylene bisimide compounds are obtained. The synthetic compound can be effectively embedded into DNA double helix base pairs of the cell nucleus and can serve as a DNA intercalator. The synthetic compound has a planar rigid structure, can be specifically enriched on a fixed tissue cell nucleus, is high in fluorescence intensity and easy in fluorescence imaging and can be compared favorably with commercial cell nucleus dyes DAPI. The synthetic compound can effectively inhibit growth of cancer cells such as U2OS, HCT116, HeLa and AGS, has an obvious antitumor effect and can be applied to preparing antitumor drugs.
Owner:BEIJING UNIV OF CHEM TECH

MOF (metal-organic framework) material with 3D-DNA network topological structure and synthesis and application thereof

The invention relates to an MOF material with the 3D-DNA network topological structure. The chemical formula is {[Cu2(HL)2NO3].NO3)n, n is a non-zero natural number, the MOF material belongs to a cubic crystal system and a (for the details of the formula, please refer to the original text) space group, is provided with 3D pore channels, meanwhile, presents a 3D-DNA double helix network topologicalstructure, and has the good thermal stability and chemical stability. The synthesis process of the material comprises the steps that ligand of H2L, a CuI acetunitrile solution, acetunitrile, HNO3, H2O are placed in a hard glass tube at the certain proportion to be sealed, and then ultrasonic treatment is conducted; a solvothermal reaction is conducted, the product is maintained for 8-16 hours atthe constant temperature of 100-140 DEG C, then the product is cooled to be at the room temperature at the speed of 3-5 DEG C / h, and vacuum excitation is conducted for 12 hours at the temperature of 100-120 DEG C. The MOF material with the 3D-DNA network topological structure can specifically bind toxic negative ions (N3-, SCN-, ClO4- and the like) in a water system, and thus the purpose of purifying the water system is achieved. Meanwhile, the MOF material is capable of rapidly identifying and efficiently removing N3-, the removing rate of N3- can reach 99% or above in a short period, and nosecondary pollution is caused.
Owner:SHANTOU UNIV

Air-cooled intercooler

The invention discloses an air-cooled intercooler which comprises a core. The core comprises an air inlet chamber, an air outlet chamber, a radiating tube and a radiating fin, two ends of the radiating tube are respectively communicated with the air inlet chamber and the air outlet chamber, and a spoiler is arranged in the radiating tube. An air inlet and an air outlet are respectively connected onto the air inlet chamber and the air outlet chamber, the spoiler is of deoxyribose nucleic acid (DNA) duplex structure, and the spoiler is formed by two frameworks of the duplex structure and a bond-shaped fin connected between the two frameworks. The air-cooled intercooler is provided with the spoiler of the DNA duplex structure and has the advantages of good heat transfer effects and small flow resistance.
Owner:SOUTH CHINA UNIV OF TECH

Preparation method and application of deoxyribonucleic acid (DNA) double-helix carbon nano-fibre and preparation method of lithium ion battery anode material

The invention discloses a preparation method and an application of a deoxyribonucleic acid (DNA) double-helix carbon nano-fibre and a preparation method of a lithium ion battery anode material. The preparation method of the lithium ion battery anode material comprises the following steps: (1) grinding, namely dissolving a binder into deionized water, fully stirring the binder to obtain a binder solution, grinding the binder solution, a conductive agent and the DNA double-helix carbon nano-fibre in a mortar, and obtaining a sizing agent for smearing; (2) evenly painting a copper foil with the prepared sizing agent and drying the sizing agent; (3) stamping the copper foil into a round electrode plate with a required dimension; and (4) putting the fabricated electrode plate into a battery cathode shell, putting the electrode plate into a vacuum drying oven, drying the electrode plate at 105 DEG C for 8 hours, taking out and weighing the electrode plate, putting the electrode plate into the drying oven again and drying the electrode plate for two hours, so as to obtain the completely dried lithium ion battery anode material. The battery anode material prepared by the method is applied to fabrication of a lithium ion battery; and the comprehensive electrochemical properties of the anode material can be greatly improved.
Owner:SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING

Conical interdigital DNA double helix bionic left-handed material

InactiveCN106299716AFlexible control with left-handed featuresIncrease production capacityAntennasElectrical conductorCoupling
The invention relates to a conical interdigital DNA double helix bionic left-handed material, and relates to a left-handed material. The conical interdigital DNA double helix bionic left-handed material is provided with a medium substrate, wherein one surface of the medium substrate is covered with a good conductor layer, an upper pair and a lower pair of crossed symmetric helix metal lines are etched on the good conductor layer, the upper and the lower pairs of crossed symmetric helix metal lines are of a mirror symmetric structure, the upper and the lower pairs of crossed symmetric helix metal lines are connected by virtue of an interdigital metal rod, the inner side of each pair of crossed symmetric helix metal lines is provided with an inward interdigital arm extending beyond an interdigital central line, and the ends of the interdigital arms are leveled to one another. By changing an arc radius of the crossed symmetric helix metal lines and the characteristics of the interdigital structural metal rod, the left-handed characteristics of the left-handed material is flexibly controlled. The conical interdigital DNA double helix bionic left-handed material is simple in structure and convenient to process; by virtue of high coupling performance of the crossed symmetric helix metal lines and the interdigital metal rod, in the case of small transmission loss and small unit electrical length, the double negative frequency band and the negative index frequency band are relatively wide, and the application field of the left-handed material is enlarged.
Owner:XIAMEN UNIV

Drilling-milling composite-type circumferential nursery garden seedling root cutting tool bit

The invention relates to the technical field of nursery garden seedling root cutting, and discloses a drilling-milling composite-type circumferential nursery garden seedling root cutting tool bit. The drilling-milling composite-type circumferential nursery garden seedling root cutting tool bit comprises a drill bit, a tool body and a rotating mandrel; the tool body is composed of milling cutter segments, the drill bit is designed by simulating the head and neck curve of a pangolin, the milling cutter segments are designed by simulating a kapok tree trunk, and kapok thorn-shaped tools are arranged in a DNA double helical mode; the drill bit and the milling cutter segments are connected and then integrally installed on the rotating mandrel; the drill bit is provided with a first chip removal groove in the axial direction of the drill bit, and the milling cutter segments of the tool body are provided with blade grooves; the tools are installed in the blade grooves; the drill tool is in tooth-embedded connection with the milling cutter segments of the tool body through dovetail grooves, and the milling cutter segments are in tooth-embedded connection with each other through dovetail grooves. According to the drilling-milling composite-type circumferential nursery garden seedling root cutting tool bit, annular or square cutting is completed through a drilling-after-milling mode, that is, the drill bit drills into a soil layer by about one meter, and then milling is performed on the soil layer through the helical milling cutter segments; the tool bit can lower the labor intensity and working noise in the root cutting process, improve the labor efficiency and prevent a danger from occurring due to close contact of people and the tools.
Owner:BEIJING FORESTRY UNIVERSITY

Efficient circumferential root cutting head for seedlings in nursery garden

The invention relates to the technical field of root cutting of seedlings in a nursery garden and discloses an efficient circumferential root cutting head for seedlings in a nursery garden. The efficient circumferential root cutting head comprises a drill bit, a cutter body and a rotating mandrel, wherein the cutter body comprises milling cutter sections, the drill bit is designed by simulating the head and neck curve of a pangolin, the milling cutter sections are designed by simulating bombax ceiba trunk, and bombax ceiba spiniform cutters are arranged in a DNA double helix manner; the drill bit and the milling cutter sections are connected and then integrally mounted on the rotating mandrel; a first chip discharge groove is axially processed in the drill bit, and blade slots are processed in the milling cutter sections of the cutter body; the cutters are mounted in the blade slots. First drilling and later milling are adopted, that is, the drill bit drills the soil layer for about one meter, then the spiral milling cutter sections are used for milling the soil layer, and annular or square cutting is completed. By means of the cutting head, the labor intensity and working noise in the root cutting process can be reduced, the labor efficiency is improved, and risk caused by close-range contact of people and the cutters is avoided.
Owner:王亚莉

Traceless yoga trousers

The invention discloses traceless yoga trousers. The trousers comprise a trouser body and elastic sheets arranged on the outer side of the trouser body, wherein the elastic sheets are connected to the trouser body through hot melt adhesive in a hot press mode, and the trouser body includes trouser legs and underpants; the trouser legs are connected with the underpants through hot melt adhesive film in a hot press mode, and the elastic sheets include trouser leg elastic sheets which are arranged on the trouser legs in a DNA double-helix shape. According to the traceless yoga trousers, the trouser legs are connected with the underpants through the hot melt adhesive film in a hot press mode, and the elastic sheets are connected to the outer surface of the trouser body through the hot melt adhesive in a hot press mode, so that traceless connection is achieved between the trouser body and the elastic sheets and between the underpants and the trouser legs; therefore, no machine sewing is needed, no impressions are produced on skin, and no projecting lines are produced when the trousers are worn, so that the trousers are comfortable and beautiful to wear.
Owner:GUANGDONG LAIDUO IND

Method for carrying out cyclic polymerization label-free fluorescence detection on PD-1 (Programmed Cell Death-1) based on nucleic acid aptamer

The invention discloses a method for carrying out cyclic polymerization label-free fluorescence detection on PD-1 (Programmed Cell Death-1) based on a nucleic acid aptamer, and relates to an establishing method and application of a fluorescence spectrum sensor in the field of a signal amplification technology. The method comprises the following steps: complementarily hybridizing a self-designed DNA (Deoxyribonucleic Acid) single chain with the PD-1 nucleic acid aptamer, adding a to-be-detected matter PD-1, and unwinding DNA double chains because a binding force between the to-be-detected matter PD-1 and the PD-1 nucleic acid aptamer is greater than the coordination ability of DNA double helices; carrying out cyclic amplification on released DNA single chains under the action of various tool enzyme, and carrying out cascade signal amplification; changing a trigger fluorescence signal of an amplification product through conformation, thus realizing high-sensitivity and high-selectivity nucleic acid optical sensory detection of the PD-1. By virtue of the method disclosed by the invention, the detection limit of the PD-1 can be up to 0.3ng / mL, and detection of the PD-1 in biological samples such as serum can be met.
Owner:OCEAN UNIV OF CHINA

DNA structured linear actuator

A DNA-structured linear actuator comprised of a ladder-like structure that twists to generate linear motion. In its base state, the DNA structured linear actuator best resembles a rope ladder. When this ladder is twisted, it takes on the appearance of a DNA double-helix structure. By application of a torsional force on one end, the ladder-like structure extends or contracts to allow linear translation of one end of the structure.
Owner:RGT UNIV OF CALIFORNIA

Preparation method of tuna extract with inhibitory effect on cancer cells

The invention discloses a preparation method of tuna extract with inhibitory effect on cancer cells, and preparation steps include compound enzyme enzymolysis, isoelectric point precipitation, ultrafiltration, nanofiltration, HPLC elution and freezing drying. The beneficial effects are that tuna protein has a lot of marine Brevibacterium oxydan secreting alkaline protease and undariapinnatifida protease cleavage sites, after the enzymolysis, lots of different lengths of peptide chains can be obtained, and the enzymolysis efficiency is high; the preparation method has the advantages of being simple, less in equipment, low in preparation cost, accurate in operation data of each step, good in repeatability, and suitable for mass production; the purity of the prepared bioactive short peptide is high, DNA double helix structure unwinding of the cancer cells can be effectively inhibited by the short peptides, so that the DNA replication of the cancer cells can be inhibited, the cancer cells stay in interphase of cell division, secretion of E-cadherin can be promoted, moveability of the cancer cells is reduced, and the transfer speed of the cancer cells is reduced.
Owner:浦江县泰如食品科技有限公司

Energy-saving stereo garage intelligent parking device

The invention provides an energy-saving stereo garage intelligent parking device. According to the device, a supporting frame is internally provided with two parking rails arranged according to a DNAdouble helix structure; each parking rail comprises semicircular plane rails arranged layer by layer, and a slope rail is connected between each pair of adjacent layers of semicircular plane rails; the top faces of the parking rails are parking faces of vehicle bearing plates, and the bottom faces of the parking rails are provided with vehicle taking rails allowing a grabbing device to walk; the slope rails are provided with steering engines used for supporting the vehicle bearing plates horizontally; an output end of a solar panel is connected with a servo motor of a rotating wheel, and the rotating wheel lifts or puts down the grabbing device by winding and unwinding a traction steel wire; a ground plate of the supporting frame is provided with a weighting device used for weighting a vehicle parking on a first upper vehicle bearing plate; a control end of the servo motor, a control end of a grabbing mechanism of the grabbing device and a control end of the steering engine are all connected with a central controller; and a signal output end of the weighting device is connected with the central controller.
Owner:ZHEJIANG UNIV OF TECH

Biology teaching and research device

InactiveCN107862959AActive disassemblyActive installationEducational modelsDetentEngineering
The invention provides a biology teaching and research device which comprises two rods and a plurality of basic group models. The two rods are arranged in a DNA (deoxyribonucleic acid) double-helix manner, two ends of each basic group model are connected on the two rods, the basic group models are parallelly arranged along the axis directions of the rods, the rods comprise metal shaping hoses, soft rubber bars are connected in the metal shaping hoses in a sleeved manner, elastic metal wires are arranged in the soft rubber bars, each basic group model comprises clamping parts and a model rod, the clamping parts are positioned at two ends of each basic group model, the model rod is positioned in the middle of each basic group model, the two clamping parts and two rods are clamped in a one-to-one correspondence manner, two ends of each model rod are in one-to-one correspondence to the two corresponding clamping parts and detachably connected with the two clamping parts, each model rod comprises two detachably connected sub models, and basic markers are arranged on sub models. According to the biology teaching and research device, the basic group models can be disassembled, the basic group models and the two double-helix rods can be disassembled, DNA models are disassembled and assembled by learners in the use process, and learning effects are improved.
Owner:宋世梅

DNA double-helix micron-scale filter element

ActiveCN106390603AIncrease surface areaPlay the effect of exhaust and decontaminationLiquid degasification by filtrationMembrane filtersMicron scaleEngineering
The invention belongs to the technical fields of heat supply, refrigeration, water supply and purification, and in particular relates to a DNA double-helix micron-scale filter element suitable for liquid exhausting and having an extremely excellent contaminant removing effect. The DNA double-helix micron-scale filter element consists of a central shaft pipe and a filter screen with a double-helix oblique cubic structure. The filter screen is welded by surface-modified metal wires to form the double-helix oblique cubic structure, the inner wall of the filter screen is welded on a central casing pipe and the filter element integrally presents the 'DNA' double-helix structure. The DNA double-helix structure filter element has stable structure, small fluid resistance and large filtering surface area, enhances the exhausting and contaminant removing effect treatment capability, and is suitable for removing free and dissolved gases from the fluid. The heating and ventilation industry needs to remove gas from the system most urgently at present.
Owner:宜兴市力克环保设备有限公司

Method for quantitative detection of activity of poly(ADP-ribose)polymerase-1 (PARP-1) based on electrochemical sensing electrode with deposited polyaniline

InactiveCN108241013AHigh sensitivityLow costMaterial electrochemical variablesPolyadenosine diphosphate ribose polymerasePolymerase L
The invention provides a method for quantitative detection of the activity of PARP-1 based on an electrochemical sensing electrode with deposited polyaniline. The method comprises the following steps:modifying a gold electrode by using a specific DNA double-helix structure with a mercapto group so as to obtain a specific unit exciting PARP-1; with a part of PARP-1 as a catalyst for nicotinamide adenine dinucleotide (NAD<+>), cleaving NAD<+> into two parts, i.e., poly(ADP-ribose) (PAR) and nicotinamide, wherein one of the two parts is used as a linking agent for linking with a PAR unit; subjecting PARP-1 to repeated catalysis so as to form a negatively-charged PAR unit; preparation of the electrochemical sensing electrode with deposited polyaniline; and detecting the generated current signals of polyaniline by using an electrochemical process so as to detect the activity of PARP-1. Unlike conventional methods for determining residual NAD<+> substrates by using enzyme-linked immunosorbent assay, the method provided by the invention can quantitatively measuring the activity of PARP-1 and is greatly improved in sensitivity. The method does not need preparation of complex materials andhas the advantages of low cost, rapidness and easiness.
Owner:HENAN UNIVERSITY

Vehicle-mounted wireless charging base vibration power generation device with high power generation efficiency

The invention specifically relates to a vibration power generation device for a vehicle-mounted wireless charging stand with high reliability, good structural stability and high power generation efficiency. The vibration generating device includes a plurality of vibrating layers parallel to each other. The vibrating layer includes a planar honeycomb grid formed by a plurality of honeycomb units. The six sides in the honeycomb unit are made of vibration generators or elastic deformation bodies. Each corner is made up of wires; the vibration generating body includes two helical generating coils coiled with each other to form a DNA double helix structure; along the axial direction of the generating coil, multiple sets of generating units are arranged between the two generating coils; in the generating unit The initial gap between the two permanent magnets can be set very small. When the gap changes, the induced current is very large, which effectively improves the power generation efficiency.
Owner:XIHUA UNIV

Preimplantation genetic evaluation system

The invention belongs to the technical field of genetic evaluation, and discloses a preimplantation genetic evaluation system, which comprises a user terminal, a personal database, a genetic detectiondata device, a data encryption module, a genetic risk analysis database, a gene sequencing module, a report data device and an evaluation server. The preimplantation genetic evaluation system can effectively and accurately evaluate embryo genes before embryo implantation, so as to ensure the survival rate of embryos and effectively select an excellent embryo for implantation; through the gene sequencing module, three kinds of fluorescent molecules are adopted to mark nucleotide for sequencing by synthesis, so that the consumption of more expensive fluorescent modified molecules and lasers isreduced, the cost is saved, molecular residue left after chemical excision is reduced, and the stability of a DNA double helix structure is not affected; the safety of genetic data is greatly improvedthrough the data encryption module, so as to prevent significant losses caused by data cracking or theft.
Owner:FUYANG NORMAL UNIVERSITY

Preparation method and application of dna double helical carbon nanofiber and preparation method of lithium ion battery negative electrode material

ActiveCN105070914BLarge first charge and discharge capacityGood reversibilityMaterial nanotechnologyCell electrodesCarbon fibersCopper foil
The invention discloses a preparation method and an application of a deoxyribonucleic acid (DNA) double-helix carbon nano-fibre and a preparation method of a lithium ion battery anode material. The preparation method of the lithium ion battery anode material comprises the following steps: (1) grinding, namely dissolving a binder into deionized water, fully stirring the binder to obtain a binder solution, grinding the binder solution, a conductive agent and the DNA double-helix carbon nano-fibre in a mortar, and obtaining a sizing agent for smearing; (2) evenly painting a copper foil with the prepared sizing agent and drying the sizing agent; (3) stamping the copper foil into a round electrode plate with a required dimension; and (4) putting the fabricated electrode plate into a battery cathode shell, putting the electrode plate into a vacuum drying oven, drying the electrode plate at 105 DEG C for 8 hours, taking out and weighing the electrode plate, putting the electrode plate into the drying oven again and drying the electrode plate for two hours, so as to obtain the completely dried lithium ion battery anode material. The battery anode material prepared by the method is applied to fabrication of a lithium ion battery; and the comprehensive electrochemical properties of the anode material can be greatly improved.
Owner:SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING

Virus-imitated DNA (deoxyribonucleic acid) polyhedral frame structure as well as preparation method and application thereof

The invention relates to a virus-imitated DNA polyhedral frame structure, which is a regular icosahedron frame structure, each edge is composed of four DNA double helixes, the virus-imitated DNA polyhedral frame structure is provided with an outer layer structure and an inner layer structure, the edges at the vertexes of the outer layer structure are bridged by five T single-stranded DNA, and the edges at the vertexes of the inner layer structure are bridged by one T. In addition, the invention further relates to a packaging and assembling composition containing the DNA material and a construction and manufacturing method of the composition. Finally, the invention also relates to application of the DNA polyhedral frame structure in the fields of nano space molecule operation level, acellular in-vitro amplification system and virus infection simulation. The DNA polyhedral frame structure recorded in the invention is a regular icosahedron, and compared with the prior art, the DNA polyhedral frame structure has a unique double-layer structure and more anchor points, so that the DNA polyhedral frame structure has better structural rigidity, and an assembly prepared from the DNA polyhedral frame structure also has better integrity and more complete packaging; and compared with the prior art, the application of the method in various fields also has substantive progress.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Quinomycin-A preparation and preparation method and application thereof

The invention discloses quinomycin-A preparation and a preparation method and application thereof. The quinomycin-A preparation comprises, by weight percent, 1-30% of quinomycin-A, 10-12% of emulsifier, and 60-89% of organic solvent. The even and stable quinomycin-A preparation is prepared by using quinomycin-A as raw material, emulsifying the quinomycin-A in a reactor by the emulsifier and mixing with the organic solvent. The preparation method is simple and low in preparation cost. After spraying, the quinomycin-A preparation is distributed on the surface of a crop in a particulate manner and accordingly is more beneficial to directly inhibiting and killing pathogenic bacteria, and drug effect is improved. The quinomycin-A preparation is efficient and low-toxicity and is pollution-free biopesticide. The quinomycin-A preparation controls disease damage mainly by breaking cell membranes of the pathogenic bacteria and inhibiting formation of DNA (deoxyribonucleic acid) double helixes. The quinomycin-A preparation is effective in controlling phytophthora caused diseases such as Phytophthora melonis Katsura, pepper phytophthora blight and pineapple heart-rot disease, less than conventional drugs in consumption, and can overcome drug resistance of phytophthora to conventional pesticides.
Owner:PLANT PROTECTION RES INST OF GUANGDONG ACADEMY OF AGRI SCI

Water-soluble cationic polyelectrolyte with end group provided with fluorophore pyrene, and preparation method and application thereof

The invention relates to a fluorescent high-molecular polymer and a preparation method of the fluorescent high-molecular polymer, in particular relates to a water-soluble cationic polyelectrolyte with an end group provided with fluorophore pyrene, a preparation method of the water-soluble cationic polyelectrolyte, and an application of water-soluble cationic polyelectrolyte in the detection of base sequences of nucleic acid molecules. A novel multi-stranded fluorescent probe is formed by electrostatic adsorption and hydrophobic interaction between the water-soluble cationic polyelectrolyte with the end group provided with fluorophore pyrene and single-stranded oligomerization nucleic acid molecules (DNAs with a hairpin structure and a linear chain structure). When nucleic acid molecules with base sequence structures complementary with those of the fluorescent probe exist, hybridization is performed through Watson-Crick base pairing principle, as the fluorescent pyrene at the end group is inserted into a DNA double-helix structure, the quenching ability of the base to the pyrene fluorescence is enhanced, so that the fluorescence intensity of the pyrene is remarkably reduced compared with that of the pyrene acted on non-target nucleic acid molecules, therefore, the specific identification of the base sequence structures of the nucleic acid molecules can be realized through difference of fluorescence properties of polyelectrolyte with fluorophore pyrene.
Owner:UNIV OF SCI & TECH BEIJING

Modular three-dimensional planting device

The invention discloses a modular three-dimensional planting device. The modular three-dimensional planting device comprises a pair of drawing type water containers, a base, a pair of module joint parts, a plurality of transverse metal supports, a plurality of spiral hollow tubes, a plurality of planting boxes, a first opening, module connection parts and a plurality of second openings, the transverse metal support is in inserted connection with the spiral hollow tube; the planting boxes are placed on the transverse metal support; the second openings are formed in the spiral hollow tubes; theplanting boxes are connected with the spiral hollow tubes through the second openings; unit planting devices are connected through the module connection parts; a DNA double-spiral planting structure is connected with the base through the module joint parts; and the drawing type water containers are arranged in the base. The modular three-dimensional planting device is simple in structure and novelin modeling; one-time complete watering can be realized; the DNA double-spiral structure is applied to the design of the three-dimensional planting device; the problems that the traditional three-dimensional planting device is simple in structure and occupies space, planting is over planar and is lack of creativity and the like are solved; and the modular three-dimensional planting device can beused for indoor and outdoor public places, and is worthy of being popularized widely.
Owner:NANJING FORESTRY UNIV

Conical interdigitated dna double helix bionic left hand material

The invention relates to a conical interdigital DNA double helix bionic left-handed material, and relates to a left-handed material. The conical interdigital DNA double helix bionic left-handed material is provided with a medium substrate, wherein one surface of the medium substrate is covered with a good conductor layer, an upper pair and a lower pair of crossed symmetric helix metal lines are etched on the good conductor layer, the upper and the lower pairs of crossed symmetric helix metal lines are of a mirror symmetric structure, the upper and the lower pairs of crossed symmetric helix metal lines are connected by virtue of an interdigital metal rod, the inner side of each pair of crossed symmetric helix metal lines is provided with an inward interdigital arm extending beyond an interdigital central line, and the ends of the interdigital arms are leveled to one another. By changing an arc radius of the crossed symmetric helix metal lines and the characteristics of the interdigital structural metal rod, the left-handed characteristics of the left-handed material is flexibly controlled. The conical interdigital DNA double helix bionic left-handed material is simple in structure and convenient to process; by virtue of high coupling performance of the crossed symmetric helix metal lines and the interdigital metal rod, in the case of small transmission loss and small unit electrical length, the double negative frequency band and the negative index frequency band are relatively wide, and the application field of the left-handed material is enlarged.
Owner:XIAMEN UNIV

A Design Method of Photoactive Logic Circuit Based on DNA Double Helix Structure

The invention belongs to the field of a DNA nanotechnology, and relates to a design method of a light-activated logic circuit based on a DNA double-helix structure. The application of realizing a biological logic function through partial optical signal transmission is the hot application of a DNA molecule logic circuit. According to the method, the DNA double-helix structure is taken as a bracket platform; a mode of encoding position information of fluorescence molecules by use of two layers of DNA strand displacement reaction is designed; and compared with a single-layer DNA strand displacement encoding mode, the mode provided by the invention has the advantages that under the condition that the numbers of fluorescence molecules are the same, the input signals is doubled. Moreover, through adoption of a fluorescence resonance energy transfer technology, the multifunctional light-activated logic circuit with multi-way input is realized.
Owner:邦奇(河南)生物技术有限公司

Method for solving allele amplification unbalance by PCR additive

InactiveCN106978484AResolving Amplification ImbalancesSolve the problem of amplification imbalanceMicrobiological testing/measurementAlleleA-DNA
The invention discloses a method for solving the imbalance of allele amplification through PCR additives. This method is aimed at the situation of unbalanced allelic amplification caused by "some alleles to be tested melt to form complex secondary structures during PCR amplification or / and DNA double-strand melts insufficiently". The method comprises the steps of: reducing the stability of double-helix DNA by adding PCR additives to the original PCR reaction system, thereby solving the problem of unbalanced allelic amplification; the original PCR reaction system is the allele to be tested The PCR reaction system used when the amplification of alleles is unbalanced in the PCR amplification of genes. Experiments have proved that this method can effectively solve the allele amplification caused by "part of the alleles to be tested melted during the PCR amplification process to form a complex secondary structure or / and DNA double-strand melts insufficiently" unbalanced.
Owner:BOAO BIOLOGICAL CO LTD +1

Preparation method of modified nanometer resin based wood lacquer

The invention discloses a preparation method of a modified nanometer resin based wood lacquer, and belongs to the technical field of coating preparation. Firstly, bisphenol A epoxy resin is used for carrying out effective modification on acrylic resin under the effect of an emulsified liquid and an initating agent. Due to the fact that the bisphenol A epoxy resin is of extremely high cohesive force and a compact molecular structure, the distribution uniformity of nanometer silver particles in a film is improved, simultaneously a compact and firm network structure can be formed on the surface of a base through a silica solution, when silver nitrate loaded on the surface of the silica solution reaches a microorganism cell membrane, silver ions are slowly released under the effect of a home-made glucose reduction solution, due to the fact that the cell membrane is of negative electricity, the microorganism cell membrane is destroyed at an extremely low concentration through the silver ions depending on coulomb force, active oxygen ion free radicals and hydroxyl free radicals are generated, a reaction can perform with bacteria, a DNA double helical structure is destroyed, metabolic disturbance plays a bacteria inhibition role, and the wood lacquer has wide application prospects.
Owner:许水仙

dna double helix micron filter

The invention belongs to the technical fields of heat supply, refrigeration, water supply and purification, and in particular relates to a DNA double-helix micron-scale filter element suitable for liquid exhausting and having an extremely excellent contaminant removing effect. The DNA double-helix micron-scale filter element consists of a central shaft pipe and a filter screen with a double-helix oblique cubic structure. The filter screen is welded by surface-modified metal wires to form the double-helix oblique cubic structure, the inner wall of the filter screen is welded on a central casing pipe and the filter element integrally presents the 'DNA' double-helix structure. The DNA double-helix structure filter element has stable structure, small fluid resistance and large filtering surface area, enhances the exhausting and contaminant removing effect treatment capability, and is suitable for removing free and dissolved gases from the fluid. The heating and ventilation industry needs to remove gas from the system most urgently at present.
Owner:宜兴市力克环保设备有限公司

Nucleotide model device

InactiveCN107507502AIncrease awareness of participationFirmly connectedEducational modelsNucleotideButt joint
The present invention discloses a nucleotide model device comprising two elongated bodies arranged in a DNA double helix, and further comprising a plurality of groups of connectors, wherein two ends of each connector are respectively connected to the two elongated bodies, a plurality of groups of connectors are sequentially arranged along the axis of the elongated bodies, each connector comprises two connecting posts in butt joint, the connecting posts are configured to have four different appearance marks, each elongated body comprises a plurality of sub-columnar bodies which are detachably connected, the center of each sub-columnar body is provided with a convex member, the convex member is provided with a first connecting portion, and two ends of the connecting post are provided with a second connecting portion and a third connecting portion respectively; the convex member is connected to the sub-columnar body through the detachable connection between the first connecting portion and the second connecting portion, and two sub-columnar bodies form one connector via detachable connection of two third connecting portions. The nucleotide model device provided by the present invention can be used by the learner to connect each element as required in a step-by-step manner into a final double helix model.
Owner:孙浩腾
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