20 results about "Helix structure" patented technology

The present disclosure provides recombinant type XVII collagen having a triple helix structure and uses thereof, which belong to the field of protein engineering technology. The recombinant type XVII collagen has an amino acid sequence formed by tandem repeats of n or more core units, where n is an integer of 1 or more, and the core unit has the amino acid sequence shown in SEQ ID NO: 1. The present disclosure also provides methods for constructing multiple expression systems and methods for preparing recombinant type XVII collagen. provide.

This invention discloses a biomimetic anchoring device based on a double-helix structure and an active adhesion mechanism, belonging to the technical field of biomimetic and marine engineering mooring equipment. Addressing the shortcomings of existing deep-water mooring anchors, such as large soil disturbance and easy failure of passive pull-out resistance, this invention provides a biomimetic anchoring structure adapted to complex seabed sediments. The device includes a rigid body, double-helix blades, and an active adhesion triggering mechanism. The rigid body consists of a solid bullet head, a central oval hollow structure, and a top conical structure. The double-helix blades adopt a variable pitch and variable diameter design, with evenly distributed grooves on the surface. The active adhesion triggering mechanism includes an anchor ring and an anchor ring piston structure, with a built-in drive motor and intelligent sensing and control module in the center. The device achieves low-disturbance penetration through double-helix micro-screwing and kinematic matching. Active adhesion is triggered under tension, forming a deep mechanical interlock and high-pressure consolidated soil crust with the soil, significantly improving pull-out bearing capacity. It is suitable for complex seabed sediments such as soft mud and gravel mixtures.

The present application is suitable for the technical field of spiral layered structure, and provides a suture-spiral composite plate bionic energy absorption structure which combines the advantages of layered spiral structure and suture structure. The structure comprises: a plurality of unit layer groups, each unit layer group comprising a plurality of unit layers, the plurality of unit layer groups being periodically arranged along the layering direction. According to the principle of bionics, the method of similarity analysis is used to confirm that the core is to compare the chitinous suture structure in the iron beetle with the selected elements to bionically generate a new energy absorption structure from the angles of structural similarity, functional similarity and boundary similarity. According to the structural feature extraction and spiral structure fusion of the chitinous characteristics in the iron beetle, a three-dimensional macroscopic preliminary suture-spiral composite plate bionic structure is established, and the range of each element and its size is determined for structure construction and size parameter optimization. The present application can reduce the mass of parts and improve the energy absorption efficiency.

A chain has: a multitude of first links that are pivotally connected to each other and form a first helical link connection that extends helically; a multitude of second links that are pivotally connected to each other and form a second helical link connection that extends helically; and a multitude of connecting components that link the first links and the second links, which correspond one-to-one to the first links, to connect the first helical link connection and the second helical link connection and to form a double helix structure.

Provided is a low-molecular-weight collagen having a 164.88° triple-helix structure. The present invention relates to small-molecule collagen, a preparation method therefor, and a use thereof. The collagen has an amino acid sequence represented by SEQ ID NO: 1 or a variant amino acid sequence after mutation of the amino acid sequence. The variant amino acid sequence retains the function of the amino acid sequence represented by SEQ ID NO: 1. The collagen has a short amino acid sequence and good transdermal absorption performance.

The disclosure relates to a brace, methods of preparation, and methods of using the brace. The brace comprises a plurality of first helix structures and a plurality of second helix structures. Each first helix winds in a first direction from a proximal end to a distal end, conforming to a contour of an object. Each second helix winds in a second direction from the proximal end to the distal end, also conforming to the contour of the object. Each first helix of the plurality of first helix structures is rotatably coupled to a corresponding second helix of the plurality of second helix structures, forming a helix pair. The first direction of the plurality of first helix structures opposes the second direction of the plurality of second helix structures.

The spiral flat coil comprises a coil body, the coil body is of a spiral structure formed by winding a flat metal strip, one end of the metal strip is arranged inside the spiral structure, and the other end of the metal strip is arranged outside the spiral structure. And the screw extends into the spiral structure from the bottom of the spiral structure. The coil body is of a spiral structure formed by winding a flat metal strip, the coil is of a planar structure, three-dimensional winding is not needed, the size is reduced by 40%, the coil is suitable for high-density integration, meanwhile, the contact area of the magnetic body and the coil is large, the temperature heat dissipation performance of the coil is improved, and the vibration resistance and impact resistance of a product are excellent.

This invention relates to the fields of interfacial water evaporation, seawater desalination, and wastewater treatment, and discloses a solar evaporator with a double-helix lateral structure. The evaporator includes a substrate with water absorption and transport functions. The outer wall of the substrate is provided with a double-helix structure capable of actively inducing micro-air convection. The double-helix structure is an axially extending double-helix groove or double-helix protrusion. During evaporation, the double-helix structure can actively disrupt the stagnant air boundary layer, enhance the outward diffusion of water vapor, and reduce the saturated vapor pressure of the lateral surface, thereby significantly enhancing the evaporation rate of the lateral surface. The core of this invention lies in a unique, functional macroscopic geometric structure, which is an integral part of the evaporator body, rather than an external attachment.

This invention discloses a three-dimensional micromixer based on the DNA double helix structure, belonging to the field of microfluidics technology. The micromixer has two spatial helical channels with a π-phase difference, periodically coupled through staggered, "base pair"-like connecting channels. The centrifugal force generated by the three-dimensional helical microchannels induces Dean's vortexes, producing a "rotation-revolution" composite effect during fluid flow. Furthermore, the mass transfer between the two channels is enhanced through the splitting-recombination effect of the "base pair" connecting channels. Compared with existing technologies, this invention has the following advantages: 1. It induces complex three-dimensional flow through the three-dimensional DNA double helix structure, realizing continuous renewal and stretching of the fluid interface; 2. It utilizes the curvature and torsion of the three-dimensional helical structure to generate a "revolution" enhanced mixing effect under the superposition effect of rotation and deflection, forming a "rotation-revolution composite flow" similar to planetary motion, overcoming the mixing difficulties caused by low diffusion efficiency and difficulty in forming chaotic convection in high-viscosity oil phase systems; 3. Under the same mixing efficiency, the pressure drop of this device is much smaller than that of traditional two-dimensional planar serpentine and split-and-merge micromixers, enabling rapid and uniform mixing of high-viscosity fluids with low energy consumption, and is particularly suitable for mixing and mass transfer enhancement of high-viscosity oil phase systems in fine chemical processes.

The ablation catheter comprises a double-helix structure, a bendable section, a catheter body and a control handle which are sequentially connected from the far end to the near end. The double-spiral structure comprises a main spiral section and an auxiliary spiral section; the main spiral sections and the auxiliary spiral sections are distributed around the same axis in a staggered mode in the same direction. The far end of the auxiliary spiral section is connected with the far end of the main spiral section through a spiral section fixing piece, or the far end of the auxiliary spiral section is provided with the spiral section fixing piece, and the spiral section fixing piece is movably connected with the main spiral section; a plurality of electrodes are arranged on the main spiral section; a wire guide cavity and a wire guide cavity which are separately arranged are formed in the main spiral section; a shaping wire cavity is formed in the auxiliary spiral section; and shaping wires are arranged in the shaping wire cavities. By means of the configuration, under the condition that the spiral section is kept soft and not prone to damaging tissue, the supporting performance of the electrode area is enhanced, the effective attaching performance is improved, and meanwhile the treatment covering area is increased.

The utility model provides a bone tissue drilling device which is composed of an outer sleeve drill bit, a built-in drill bit, a drill rod and a clamping head, and the built-in drill bit is arranged inside the outer sleeve drill bit in a sleeved mode. The outer sleeve drill bit is provided with a limiting piece and a sawtooth blade is arranged at the top end of the outer sleeve drill bit, so that the bone tissue cutting range and depth can be locked and the bone tissue can be longitudinally cut; the built-in drill bit is a double-helix drill bit, two same fan-shaped blades are arranged at the top end of the built-in drill bit and can transversely cut and smash the longitudinally cut bone tissue, and a chip groove is formed by the double-helix structure of the built-in drill bit and can discharge the smashed bone tissue through the chip groove. The bone tissue drilling device is simple in structure, smashing and cleaning of bone tissue within a controllable range are achieved, and bone drilling efficiency and accuracy are greatly improved.

The invention relates to chemical compounds useful as structural mimetics of peptides comprising proline-rich helix structures, preferably polyproline-type II (PPII) helix structures. The invention further relates to the medical use of the chemical compounds in the treatment of a medical condition associated with a modified intracellular signal transduction process mediated by a proline-rich helix structure and a protein having a binding domain binding to said proline-rich helix structure such as an infectious disease, immune disease, neurological disease, cardiometabolic disease and a cancerous disease. The invention further relates to pharmaceutical compositions comprising a compound of the present invention or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. The invention further relates to an in vitro method for modifying an intracellular signal transduction process mediated by a proline-rich helix structure, comprising contacting a compound of the invention with a biological cell.

The medicament delivery device dispenses a drug in multiple pre‑defined doses. It contains a plunger‑rod assembly, i.e., a main rod and an auxiliary rod (8) that are rotationally coupled, plus a biasing member that pushes the assembly proximally. A user‑operated loading mechanism is activated by twisting a element; this rotation translates the auxiliary rod and pre‑loads the biasing member. The loading mechanism comprises a helical feature (142 / 143) on either the auxiliary rod or the base and a cooperating feature (240) on the opposite part. The helix has two sections with different leads (142a / 143a and 142b / 143b); the cooperating feature provides two matching support faces (241 and 242). During loading, face 241 engages the first helix section, then face 242 engages the second, producing the required translational movement and spring bias.

The utility model discloses a kind of six-leaf spherical bone drill, it is related to medical instrument field, wherein, six-leaf spherical bone drill includes: front end spherical tool bit, middle straight rod body and rear end limiting connection structure composition, wherein, the front end spherical tool bit includes six-leaf helical cutting edge, the structure of helical cutting edge is spherical helix structure;The diameter of the front end spherical tool bit is D1, wherein, 1.60mm≤D1≤4.40mm;The helix angle of six-leaf helical cutting edge set in the front end spherical tool bit is angle1, wherein, 27°≤angle1≤33°;Six-leaf spherical bone drill provided by the utility model is used for the bone in fresh tooth extraction nest, uneven alveolar ridge top to take out bone mud can be used in periodontal surgery to cover exposed tooth root, assist tooth firmness;The bone mud removed can be used in implant surgery to increase, widen in operation area, cover exposed implant surface, improve the survival rate of implant.

The invention belongs to the technical field of supporting frames, and particularly relates to an auxiliary supporting and adjusting frame for arc-shaped component construction. According to the scheme, the auxiliary supporting and adjusting frame comprises a power mechanism, and a lifting mechanism is arranged at the top of the power mechanism; the lifting mechanism stretches out and draws back through a double-helix structure; the supporting mechanism is arranged at the top of the lifting mechanism, and the lifting mechanism drives the supporting mechanism to move up and down; the lifting mechanism comprises a fixed protection shell which is fixedly arranged at the top of the power mechanism; and the bottom of the supporting ring is fixedly arranged at the top of the fixed protection shell. A lower rotating rod and an upper rotating rod penetrate through the middles of threaded cylinders at the ends of a fixed protective shell and a movable protective shell in a threaded mode, the lower rotating rod rotates to move upwards in the middle of the threaded cylinders at the ends of the fixed protective shell, and the movable protective shell moves upwards or downwards through external threads on the surfaces of the lower rotating rod and the upper rotating rod; the ratio of the rotating angle of the upper rotating rod to the up-and-down moving distance of the movable protective shell is about two to one, and the height can be rapidly adjusted.

This invention discloses a double-stranded biomimetic radiation shielding structure and its manufacturing method, comprising a plurality of shielding units arranged in an array. Each shielding unit includes a first single strand for absorbing gamma rays, a second single strand for absorbing neutrons, and a shell for supporting and slowing down neutrons. The first and second single strands are helically wound according to a double-stranded DNA helix structure to form a cylindrical core. The shell wraps around the outside of the core, making the outer shape of the shielding unit a regular prismatic shape. This invention designs a lightweight and efficient polymer-based radiation shielding structure capable of slowing down and timely absorbing neutrons and gamma rays in all directions, and proposes an additive manufacturing method adapted to this shielding structure, ensuring its feasibility in principle and its manufacturability.

The invention discloses a micro-nano machine with a magnetic control spiral structure and a preparation method and application of the micro-nano machine with the magnetic control spiral structure, the micro-nano machine with the magnetic control spiral structure takes a spirulina biological template as a matrix, and the surface of the matrix is coated with a magnetic metal coating. According to the magnetic control micro-nano machine disclosed by the invention, the sperm carrying magnetic control micro-nano machine is prepared by a chemical plating method based on a biological template and a mechanical cutting method based on magnetic field arrangement, and the obtained magnetic control micro-nano machine has good manufacturing cost performance, size uniformity and biocompatibility; the magnetic control micro-nano machine is applied to sperm carrying, a spirulina biological template matched in size is selected, and the magnetic control spiral structure micro-nano machine can penetrate into the sperm from the tail of the sperm to realize sperm carrying by changing the direction of a rotating magnetic field. In the experimental test of the invention, the magnetic control spiral structure micro-nano machine realizes complex path movement under the rotation control; and at the movement speed of 15 mu m / s, the precise and quick-response movement capability is realized.

This invention provides a spiral packing for wellhead sealing of an oil pumping unit and its preparation method, relating to the field of oil and gas exploration equipment technology. It addresses the problems of high friction coefficient, short service life, and poor resistance to wear in existing packing technologies. The invention forms a double-helix structure by nesting the rectangular helixes of a first packing between the rectangular helixes of a second packing. The first packing has a higher hardness and lower elasticity than the second packing. This double-helix structure, with its different hardness and elasticity, forms a spiral-sealed chamber with the polished rod during axial compression. This prevents continuous impact of oil and gas pressure on the packing, ensuring a sufficient seal between the packing and the polished rod while reducing the friction coefficient and improving the packing's service life. Furthermore, in cases of misalignment during pumping unit installation, the second packing extends further in the direction of wear, thus maintaining the packing's sealing performance.

Provided is a large-scale biological method for preparing collagen having 164.88° triple helix structure. Provided is a method for constructing a yeast cell expressing collagen, comprising introducing a recombinant expression vector into the yeast cell, wherein the recombinant expression vector comprises a polynucleotide encoding the collagen, wherein the collagen comprises repeating units of the sequence as shown in SEQ ID No. 1, the number of the repeating units is 2-32, and the repeating units are directly linked. The collagen is recombinant type III humanized collagen, preferably collagen having a 164.88° triple helix structure. The present disclosure achieves large-scale production of a recombinant humanized collagen which has a 164.88° triple helix structure and belongs to type A by engineering a "chassis strain", and can meet the market demand through large-scale production.

This invention provides a spiral packing for wellhead sealing of an oil pumping unit and its preparation method, relating to the field of oil and gas exploration equipment technology. It addresses the problems of high friction coefficient, short service life, and poor resistance to wear in existing packing technologies. The invention forms a double-helix structure by nesting the rectangular helixes of a first packing between the rectangular helixes of a second packing. The first packing has a higher hardness and lower elasticity than the second packing. This double-helix structure, with its different hardness and elasticity, forms a spiral-sealed chamber with the polished rod during axial compression. This prevents continuous impact of oil and gas pressure on the packing, ensuring a sufficient seal between the packing and the polished rod while reducing the friction coefficient and improving the packing's service life. Furthermore, in cases of misalignment during pumping unit installation, the second packing extends further in the direction of wear, thus maintaining the packing's sealing performance.