Vagina administration medicine for treating and preventing woman vagina inflammation and preparation method thereof

A technology for vaginal drug administration and vaginitis, applied in the field of medicine and health, can solve the problems of single dosage form and treatment failure, and achieve the effects of high bioavailability, convenient medication, and convenient transportation

Inactive Publication Date: 2007-07-18
RENHE GRP DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The invention provides a traditional Chinese medicine composition and its preparation method and its quality control method, and provides safe and effective medicines for treating such diseas...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Take 40g of alum (calcined) and grind it into fine powder, pass through a 140 mesh sieve, and set aside; take 200g of rhubarb, 200g of honeysuckle, and 200g of Angelica dahurica as group A; The two groups were decocted twice with 10 times the amount of water for the first time, decocted for 1.5 hours, added 8 times the amount of water for the second time, decocted for 1 hour, filtered, combined filtrates, and concentrated to a relative density of 1.10-1.25 ( 50°C), cool to room temperature, add 2 times the amount of ethanol, stir well, let it stand for 24 hours, filter, recover ethanol from the filtrate, concentrate to a relative density of 1.10-1.25 (50°C), combine A and B concentrates, spray Dry, spray dry powder, set aside. Add the fine powder of alum (calcined) to the above-mentioned spray-dried powder, and mix well; take 7 g of borneol and add a small amount of ethanol to dissolve it, add it to the above mixture, mix well, and prepare the medicine fine powder for l...

Embodiment 2

[0056] Take 40g of alum (calcined) and grind it into fine powder, pass through a 140 mesh sieve, and set aside; take 200g of rhubarb, 200g of honeysuckle, and 200g of Angelica dahurica as group A; The two groups were decocted twice with water respectively, adding 10 times the amount of water for the first time, decocting for 1.5 hours, adding 8 times the amount of water for the second time, decocting for 1 hour, filtering, combining the filtrates, and concentrating to a relative density of 1.12-1.15 ( 50°C), cool to room temperature, add 2 times the amount of ethanol, stir well, let it stand for 24 hours, filter, recover ethanol from the filtrate, concentrate to a relative density of 1.12-1.15 (50°C), combine A and B concentrates, concentrate To form a thick paste, add the fine powder of alum (calcined) into the above thick paste, and mix well; get 7 g of borneol and add a small amount of ethanol to dissolve it, add it to the above mixture, mix well, and prepare the medicinal e...

Embodiment 3

[0062] Get 800g of alum and 140g of borneol and pulverize into fine powder, sieve, and set aside. Take 4000g of rhubarb, 4000g of honeysuckle, 4000g of Angelica dahurica as group A; The two groups were decocted twice with water respectively, adding 10 times the amount of water for the first time, decocting for 1.5 hours, adding 8 times the amount of water for the second time, decocting for 1 hour, filtering, combining the filtrates, and concentrating to a relative density of 1.12-1.15 ( 50°C), cool to room temperature, add 2 times the amount of ethanol, stir well, let stand for 24 hours, filter, recover ethanol from the filtrate, concentrate to a relative density of 1.16-1.18 (50°C) extract, combine A and B extract , adding alum (calcined) fine powder and borneol fine powder to the above-mentioned thick paste, mixing evenly, to obtain medicinal extract for subsequent use; get micropowder silica gel 1000g, cross-linked polyvinylpyrrolidone 900g, microcrystalline cellulose appro...

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PUM

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Abstract

A Chinese medicine in the form of soft-capsule, tablet, or capsule for preventing and treating vaginitis, pudendal itching, morbid leukorrhea, etc and preventing venereal disease is prepared from 7 Chinese-medicinal materials including rhubarb, hineysuckle flower, alum, borneol, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a medicine for treating and preventing women's vaginitis and a preparation method thereof, belonging to the field of medicine and hygiene. Background technique [0002] Vaginitis is an inflammation of the vaginal mucosa and submucosal connective tissue, and is a common disease in gynecological clinics. Clinically, vaginitis is characterized by changes in the characteristics of leucorrhea and vulvar itching and burning pain. The vagina has a natural defense function against the invasion of pathogens. When the natural defense function of the vagina is destroyed, pathogens are easy to invade and cause vaginal inflammation. Common vaginitis includes bacterial vaginitis, trichomonas vaginitis, fungal vaginitis, senile vaginitis, etc. In recent years, trichomonas The incidences of vaginitis and fungal vaginitis are on the rise. Therefore, it is very necessary to explore a drug for the treatment of such diseases. On January 19, 200...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K9/00A61K9/20A61K9/48A61P15/02A61P31/04A61P33/02A61K33/06A61K31/045
Inventor 杨文龙
Owner RENHE GRP DEV CO LTD
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