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Medicinal composition for treating coronary heart disease and preparation process thereof

A composition and coronary heart disease technology, applied in the direction of drug combination, test drug preparation, medical formula, etc., can solve problems such as ineffective qi and blood circulation

Inactive Publication Date: 2008-03-19
山西太行药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Deficiency in origin is mainly qi deficiency, and excess in superficiality is mainly blood stasis. Therefore, in the treatment, it should be based on nourishing qi and activating blood circulation. There are many medicines that use invigorating qi and activating blood circulation as the main treatment method in the current oral preparations, and they have also achieved good results. curative effect, but there is no medicine for nourishing qi and promoting blood circulation in solid preparations and injections that are more suitable for the treatment of coronary heart disease.

Method used

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  • Medicinal composition for treating coronary heart disease and preparation process thereof
  • Medicinal composition for treating coronary heart disease and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] Astragalus extract 50kg and Salvia miltiorrhiza extract 150kg are made into capsules according to conventional methods, each 0.3g, 3 capsules per day.

Embodiment 2

[0118] Astragalus extract 100kg was prepared by conventional boiling and alcohol precipitation method, and 80kg of Salvia miltiorrhiza extract was prepared by conventional boiling and alcohol precipitation method. The tablets were prepared according to the conventional method, each 0.3g, 3 tablets per day.

Embodiment 3

[0120] Astragalus extract 75kg was prepared by conventional boiling and alcohol precipitation and column method, and 113kg of Salvia miltiorrhiza extract was prepared by conventional boiling and alcohol precipitation and column method. The oral liquid was prepared according to the conventional method, each 10ml, 3 bottles per day.

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Abstract

The invention discloses a drug combination for remedying the coronary heart disease and the preparation method and quality control method of the drug combination. The drug combination consists of an extract of a milkvetch root and the extract of a red salvia root. The preparation method of the drug combination is that the extract of the milkvetch root and the extract of the red salvia root are dissolved in the water for injection; the pH value is regulated; active carbon is added into the solution to be boiled and sealed for refrigerating, filtering; the filtrate is added with the active carbon to be boiled and filtered; the filtrate is respectively filtered by a microporous filtering film again; the water for injection is added into the filtrate for filling, freezing and drying to obtain the drug combination. The efficacy of drug combination is benefiting qi and activating blood circulation, and the drug combination has obvious effect of remedying the coronary heart disease and especially the angina, which is caused by the coronary heart disease.

Description

Technical field [0001] The invention relates to a pharmaceutical composition and a preparation method and quality control method thereof, in particular to a pharmaceutical composition for the treatment of coronary heart disease, and a preparation method and quality control method thereof. Background technique [0002] With the aging of the society and the influence of modern diet, environment and other factors, the incidence of cardiovascular diseases, mainly coronary heart disease and angina pectoris, is increasing, and the research on cardiovascular disease drugs has also been paid much attention. At present, there are a large number of drugs for the treatment and prevention of coronary heart disease in clinical medicine. The main commonly used drugs are: vasodilator drugs to improve symptoms include nitrate drugs, such as nitroglycerin, calcium antagonists, such as nifedipine, β- Receptor blockers, such as propranolol, antiplatelet aggregation and other therapeutic and prevent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/16A61K9/19A61K9/20A61K9/48A61P9/10G01N30/02G01N33/15
Inventor 屠鹏飞王亚玲李林葆王瑛
Owner 山西太行药业股份有限公司