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Agent for enhancing collagen production and utilization of the same

An enhancer and enhancement technology, applied in the field of collagen production enhancer and composition for collagen production enhancement, can solve the problems of no record, no suggestion, no one's attention, etc.

Inactive Publication Date: 2008-07-30
HAYASHIBARA BIOCHEMICAL LAB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, although the use of α,α-trehalose as an excipient of a collagen production enhancer is also disclosed (see, for example, JP-A-2003-171290), these documents neither describe nor suggest the use of α,α-trehalose The glycosylated derivatives of α-trehalose and / or α,α-trehalose exert a remarkable enhancing effect on collagen production induced by L-ascorbic acids, and so far, no one has noticed that α,α-trehalose and / or or glycosylated derivatives of α,α-trehalose can enhance collagen production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086]

[0087] Mix the following ingredients evenly according to the following ratio to prepare a collagen production enhancer.

[0088] Hydrous crystalline α,α-trehalose (sold by Hayashibara Shoji Co., Ltd., trade name "Toreha")

[0089] 49 parts by mass

[0090] L-Ascorbic acid 2-glucoside (sold by Hayashibara Biochemical Laboratory Co., Ltd., trade name

[0091] "AA2G") 1 part by mass

[0092] This product shows the effect of enhancing collagen production, has a moisturizing effect on the skin, and can effectively prevent skin aging. It is a kind of collagen production enhancer that can be used easily and shows significant effects. In addition, this product has a good taste due to its moderate sourness, so it can be attached with a text mark that enhances collagen production. As a health supplement that enhances collagen production, it can be ingested directly or dissolved in water. Or other beverages, etc., these two way...

Embodiment 2

[0095]

[0096] The following ingredients are evenly mixed according to the following proportions to prepare a powdered health supplement for enhancing collagen production. This product was diluted with the same D-MEM medium as used in Experiment 1 above, and the collagen production-enhancing activity of this product was measured according to Experiment 1 to confirm that the activity was exerted.

[0097] 5 parts by mass of L-ascorbic acid

[0098] Antler ganoderma (sold by Hayashibara Biochemical Research Institute Co., Ltd.) 1.5 parts by mass

[0099] Polygonum indigo (sold by Hayashibara Biochemical Laboratory Co., Ltd.) 1.5 parts by mass

[0100] Syrup containing α, α-trehalose (Hayashibara Co., Ltd.

[0101] (trade name "Hallodex") 25 parts by mass

[0102] Hydrous crystalline α, α-trehalose (produced by Hayashibara Shoji Co., Ltd.

[0103] sold, trade name "Toreha") 10 parts by mass

[0104] This product has been shown to enhance collagen production, therefore, it...

Embodiment 3

[0107]

[0108] The following ingredients are evenly mixed according to the following proportions to prepare a powdered health supplement for enhancing collagen production. After preparation, it was confirmed that the collagen production enhancer was stable and exhibited a collagen production enhancer effect.

[0109] Hydrous crystalline α, α-trehalose (Hayashibara Corporation

[0110] sold, trade name "Toreha") 5.5 parts by mass

[0111] L-Ascorbic acid 2-glucoside (produced by Hayashibara Trading Co., Ltd.

[0112] 1.5 parts by mass

[0113] Chondroitin Sulfate Sodium 1 part by mass

[0114] Chitosan 1 part by mass

[0115] Turned sugar rutin (sold by Hayashibara Trading Co., Ltd., trade name

[0116] "αG rutin") 1 part by mass

[0117] Adenosine monophosphate 0.1 parts by mass

[0118] Coenzyme Q10 0.05 parts by mass

[0119] This product has been shown to enhance collagen production, therefore, it can be used as a health supplement to enhance collagen production....

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PUM

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Abstract

It is intended to provide a means exerting a prolonged effect of enhancing the production of collagen. This object can be achieved by an agent for enhancing collagen production which contains, as the active ingredient, alpha, alpha-trehalose and / or a sugar derivative of alpha, alpha-trehalose, or a composition for enhancing collagen production which contains the agent for enhancing collagen production as described above.

Description

technical field [0001] The present invention relates to a novel collagen production-enhancing agent and a composition for enhancing collagen production. Enhancer and composition for enhancing collagen production containing the collagen production enhancer. Background technique [0002] Now, entering the aging society, many middle-aged and elderly people in the world, especially women, are troubled by changes in skin thickness, metabolism, and bone density caused by aging. In particular, changes in appearance that are noticeably felt on the face accompanied by fine lines and wrinkles, occurrence of sagging skin, loss of tension, and decrease in elasticity are representative phenomena. Until now, cosmetics containing mucopolysaccharides such as collagen and hyaluronic acid have been developed as anti-aging cosmetics in order to ensure moisture retention of the skin. However, these cosmetics cannot provide sufficient skin anti-aging effects. In recent years, research on aging...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7016A23G9/00A23L1/30A23L2/52A61K8/60A61K31/122A61K31/375A61K31/7008A61K31/702A61K31/7048A61K31/7076A61K31/726A61P17/16A61P1/02A61P43/00A61Q11/00A61Q19/00C07H3/04C07H3/06
CPCA61K8/602A61K31/702A61K8/736A61K31/7016A23L1/30A23G9/34A61K8/735A61Q19/08A61K31/375A61K8/606A61K31/122A23V2002/00A61K8/676A61K8/355A61K31/7076A61K31/726A61K31/7048A61K31/7008A61K8/498A23L2/52A23L33/10A61P1/02A61P17/00A61P17/16A61P43/00A61K8/60
Inventor 宫田聪美牛尾慎平岩城完三三宅俊雄
Owner HAYASHIBARA BIOCHEMICAL LAB INC
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