Uses of choline esterase in skin nursing material for treating or improving the skin symptom

A technology for skin care and skin improvement, which is applied in the application field of skin care compositions, can solve problems such as skin damage, and achieve the effects of small side effects, wide sources, and suitable for industrialization

Inactive Publication Date: 2008-10-15
SHENZHEN DINGXIN BIO MEDICINE TECH DEV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Medical cosmetology, tattooing, eyebrow tattooing and other cosmetic surgery, and minor trauma such as minor burns, solar dermatitis and drug-induced dermatitis, etc., often cause skin damage, redness, pain and even inflammation, as well as more serious skin diseases and Microbial infection, the need to eliminate discomfort, improve skin symptoms or improve appearance at this time is far from being met by relying on existing skin care products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0043] 1. Freeze-dried powder: cholinesterase enzyme liquid (enzyme activity 100U)+PEG4000 0.2% (antifreeze), quantitatively packed in ampoules or vials. -28C cryopreservation. When used, it is diluted with purified water in different times according to different purposes, and applied directly with or without other auxiliary substances, or added to other skin care products as auxiliary agents.

[0044] 2. Aqueous solution 1: cholinesterase enzyme freeze-dried powder (enzyme activity 100U) + deionized water 80 ml + PEG400 10% + dextran 40 5% + mannitol 5% + phenol 0.25 + m-cresol 0.3%, subpackaged vial, keep refrigerated.

[0045] 3. Aqueous solution 2: Freeze-dried cholinesterase powder (enzyme activity 100U) + 70 ml of normal saline + 30% medical glycerin (+ 0.3% p-chloro-m-cresol) sub-packaged, stored at room temperature, with a storage period of six months .

[0046] 4. Soft capsules: cholinesterase enzyme freeze-dried powder (enzyme activity 100U) + deionized water 35 m...

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PUM

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Abstract

The invention relates to an application of cholinesterase in preparing skin caring products for treatment or improvement of skin symptoms. The skin caring products can be applied on surface skin, hair, oral lip mucosa and genital tract surface of human body by smearing, spraying or other manners to achieve cleaning, protecting, repairing, health keeping, appearance improving, skin caring and decorating purposes. The skin caring products include, but not limited to, lyophilized power, solution, electuary, cream, emulsion, spray, water gel, and soft capsule. The cholinesterase can, after being applied on the skin of human or mammalians, deactivate P substance or other tachykinins released by skin nerve ending, inhibit skin excess immunological reaction or inflammation, relieve skin symptoms, and eliminate discomfort or trouble of a user.

Description

technical field [0001] The present invention relates to the application of cholinesterase in skin care products for treating or improving skin symptoms, in particular to the application of cholinesterase in skin care compositions for antagonizing tachykinin-mediated skin symptoms. Background technique [0002] Tachykinins (TKs) are a group of peptides with the following series of common amidated carboxy-terminals. Tachykinin C-terminus has -Phe-X-Gly-Leu-Met-NH 2 The common structure is a similar pharmacologically active neuropeptide produced in mammals, including humans, with a variety of physiological functions. The name of tachykinins comes from their stimulating effect on smooth muscle tissue. Mammalian tachykinins mainly include Substance P (Substance P, SP), Neurokinin A (Neurokinin A, NKA) and Neurokinin B (Neurokinin B, NKB). Tachykinins are widely distributed in the central nervous system and peripheral nervous system, released by nerves, and can also be produced ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/66A61K38/46A61K9/19A61K9/10A61K9/48A61K9/107A61K9/12A61Q19/00A61P17/02A61P17/16A61P1/02A61P17/04A61P17/10A61P31/12A61P31/10A61P31/04A61P33/00
CPCY02A50/30
Inventor 徐汉虹陶国良
Owner SHENZHEN DINGXIN BIO MEDICINE TECH DEV
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