Automated batch manufactuirng

An automatic management, batch technology, applied in the direction of program control, computer control, comprehensive factory control, etc., can solve problems such as batch discarding

Inactive Publication Date: 2009-01-07
PFIZER PRODS ETAT DE CONNECTICUT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Thus, if there are quality control issues, batches already produced may have to be discarded

Method used

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  • Automated batch manufactuirng
  • Automated batch manufactuirng
  • Automated batch manufactuirng

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Embodiment Construction

[0041] The present invention includes an integrated automated manufacturing system with override computer control, with particular application to batch manufacturing processes of chemical and food products, especially pharmaceuticals and biological products. A closed information loop is achieved from initial design to feedback evaluation comparing the (planned) design with actual production events with real-time comparisons to the selections made to automatically modify the plan.

[0042] Batch systems generally involve the production of at least two products on one line or at one production site, requiring sharing of resources and production time. The manufacturing system of the present invention includes a design modeler component for designing a manufacturing process (design module) utilizing:

[0043] i. Process (overall production process, e.g. synthetic steps in the production of chemicals and pharmaceuticals) models,

[0044] ii. a factory (consideration of factory res...

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Abstract

The invention provides an integrated automated management system for batch manufacturing of products, particularly pharmaceuticals. The system comprises: a distributed data with process related information, a design module which extracts information to build operating models for the manufacturing; a planning module which interacts with the data base and design module to provide the financial and scheduling aspects of the manufacturing, and an exploring module, interfaced with the data base and the other modules, in a closed operational loop to provide real time analysis of the operating model in comparison to actual manufacture to provide real time quality control.

Description

technical field [0001] The present invention relates to automated manufacturing management systems for industries such as pharmaceutical, chemical, food and beverage, cosmetic and other process manufacturing, and to discrete manufacturing such as electronics and vehicles, in particular to pharmaceutical Batch manufacturing (batchmanufacturing) design, planning and quality control of production. Background technique [0002] The most widely applicable standards for manufacturing control systems in the United States and Europe are ISA S88.01 and IEC 61512-01, respectively (the disclosure of which is incorporated herein by reference as it is known in the art). These standards relate to various models such as equipment models and recipe models, as well as various modules and components involved in manufacturing and batch control. The terms and methods used below are specific to those defined in such standards, especially those defined in ISA S88.01 (S88). [0003] Many practic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06Q10/00G06Q10/06G06Q50/04
CPCG05B15/00G06Q10/06G05B19/4187G05B2219/31336G05B2219/32258G05B2219/32363Y02P90/02Y02P90/80G06Q50/04G05B19/418
Inventor 凯瑟尔·约瑟夫·斯特恩阿达姆·马修·拉隆德理查德·威廉·金勃尔马济迪·哈扎勃
Owner PFIZER PRODS ETAT DE CONNECTICUT
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