Theory immune response prediction system for multi-epitope vaccine and control method thereof

A technology of immune response and control methods, which is applied in special data processing applications, calculations, applications, etc., and can solve problems such as large differences in theoretical immune response rates

Inactive Publication Date: 2011-02-02
SHANDONG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the highly heterogeneous population genetic structure of HLA in the population, the theoretical immune response rate of the same epitope vaccine used in different populations will vary greatly

Method used

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  • Theory immune response prediction system for multi-epitope vaccine and control method thereof
  • Theory immune response prediction system for multi-epitope vaccine and control method thereof
  • Theory immune response prediction system for multi-epitope vaccine and control method thereof

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Embodiment Construction

[0050] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0051] figure 1 Among them, the theoretical immune response rate prediction system for Chinese HLA-restricted multi-epitope vaccine design has at least one client unit 1 for inputting the inquired information and displaying the corresponding prediction graph; this unit communicates with the server-side program unit through a wired or wireless network 2, and access the WEB server 4 and the database 3 through this unit; the database 3 is equipped with a data processing unit, which analyzes the required data graphics according to the user's selection, and provides them to the client after integration. The figure contains a map of China , using different colors on the map to represent the population distribution of the combination. The manager can enter the background management unit to modify the 5 system, and the visitor can only browse through the WEB s...

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Abstract

The invention discloses a theory immune response rate forecasting system of multiple-epitope vaccine design and control method thereof. The system at least has a user terminal unit for inputting the enquiry information and displaying the enquiry result; the unit is connected with a server terminal program unit by a wired or wireless network and accesses a WEB server and a database by the server terminal program unit; the database is provided with a data processing unit for analyzing the provided data pattern and supplying the integrated the data pattern to the user terminal; the database is connected with the WEB server; a background management unit is connected with the WEB server and the database. The system and the control method referred by the invention can implement multiple-epitopevaccine theory immune response rate forecasting result proceeding, standardizing and visualizing expressions and networking exhibition and enquiry.

Description

technical field [0001] The invention relates to a theoretical immune response rate prediction system and a control method thereof, in particular to a theoretical immune response rate prediction system and a control method for Chinese HLA-A, B site-restricted multi-epitope vaccine design. Background technique [0002] Vaccines are antigenic substances used to induce immune responses in the body. The traditional method of preparing vaccines is to prepare various dead vaccines, live attenuated vaccines and subunit vaccines by cultivating pathogenic microorganisms. These vaccines have so far been successfully used to prevent the occurrence and prevalence of many infectious diseases. However, although the vaccines prepared by these traditional methods have achieved remarkable effects, there are also problems such as biological hazards and genetic variation that cause the original vaccines to lose efficacy. Moreover, not all pathogens can be successfully prepared for their vaccin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06F19/00A61B19/00G01N33/48A61B90/00
Inventor 薛付忠成玉
Owner SHANDONG UNIV
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