Improvement effect of blood-nourishing and brain-refreshing granules on cerebral microcirculatory disturbance

Abstract

The invention relates to the new application of a preparation of Chinese traditional medicine, in particular to the improvement effect of blood-nourishing and brain-refreshing granules on the cerebral microcirculatory disturbance. The test data indicate that the blood-nourishing and brain-refreshing granules can restrain the cerebral microcirculatory disturbance and cerebral nerve trauma; and the effect can be related to the restraint on the production and death of the peroxide.

Description

Technical field: [0001] The invention relates to a new application of a traditional Chinese medicine preparation, in particular to the improvement effect of the traditional Chinese medicine Yangxue Xuenao Granule on cerebral microcirculation disturbance. Background technique: [0002] The average incidence rate of cerebrovascular diseases in the world is 140-200 / 100,000 population, and the average death rate is 100 / 100,000 population, which is a disease with high morbidity and mortality. Improving cerebrovascular injury is of great significance to saving lives and reducing medical costs. Cerebrovascular injury caused by ischemia-reperfusion accounts for about 60% of the causes of cerebrovascular injury. The peroxide produced after ischemia-reperfusion degrades I-κB, activates NF-κB, and the subunit of NFκB enters the nucleus, activates adhesion molecules, inflammatory factors and apoptosis-related gene loci, and promotes the expression of adhesion molecules. The release of...

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Problems solved by technology

However, there is no report on whether Yangxue Xuenao Granules can improve the cerebral microcirculation disorder caused by ischemia-reperfusion.

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