Amaranth berberine tablet and preparation method thereof

A technology of berberine and amaranth, applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of increased osmotic pressure in the intestinal cavity, decreased digestion and absorption capacity, and inability to play a therapeutic role and other problems, to achieve the effect of increasing the burden on the stomach, reducing the dosage, and good moisture-proof performance

Active Publication Date: 2009-09-23
FUZHOU JINXIANG CHINESE MEDICINE PHARMA
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are too many types of traditional Chinese medicines used to treat this disease, and the ingredients are too complicated. In the case of spleen and stomach qi deficiency caused by diarrhea, the digestion and absorption capacity is greatly reduced. A large number of redundant ingredients not only cannot play a therapeutic role, but also increase the burden on the stomach and slow down The condition improves, especially some ingredients are not easy to absorb, stay in the stomach, increase the osmotic pressure in the intestinal cavity, and aggravate the diarrhea

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Taking the preparation of 1000 amaranth berberine tablets as an example, the preparation method is:

[0029] (1) The amount of raw materials for the main components is:

[0030] Amaranth 1667g; Licorice 266g; Berberine hydrochloride 33.3g;

[0031] (2) 266g of Radix Glycyrrhiza is ground into fine powder, for subsequent use;

[0032] (3) Add water to decoct 1667g of amaranth for two times, the decoction temperature is 100°C, the first time is 1.5 hours, the second time is 1 hour, the decoction is combined, filtered, and the decoction is at a vacuum degree of 0.08 and 75°C Concentrate into a thick paste with a relative density of 1.20 (75°C). Add step (2) fine powder of licorice to the thick paste, mix well, dry in vacuum at a low temperature of 65° C., and pulverize into 100-mesh fine powder. Combine the decoctions, filter, take the supernatant and concentrate into a thick paste, add fine powder of licorice, mix well, dry at low temperature, crush into fine powder, a...

Embodiment 2

[0038] Taking the preparation of 1000 amaranth berberine tablets as an example, the preparation method is:

[0039] (1) The amount of raw materials for the main components is:

[0040] Amaranth 1667g; Licorice 280g; Berberine hydrochloride 35g;

[0041] (2) the Radix Glycyrrhizae of above-mentioned formula quantity is pulverized into fine powder, for subsequent use;

[0042] (3) Decoct the iron amaranth in the amount of the above formula twice with water at 100°C, for 1.5 hours for the first time, and for 1 hour for the second time, combine the decoction, filter, and decoct at a vacuum degree of 0.08 , Concentrated at 75°C to a thick paste with a relative density of 1.20 (75°C). Add step (2) fine powder of licorice to the thick cream, mix well, dry in vacuum at a low temperature of 50° C., and pulverize into 100-mesh fine powder. Combine the decoctions, filter, take the supernatant and concentrate into a thick paste, add fine powder of licorice, mix well, dry at low temperatu...

Embodiment 3

[0048] Taking the preparation of 1000 amaranth berberine tablets as an example, the preparation method is:

[0049] (1) The amount of raw materials for the main components is:

[0050] Amaranth 1667g; Licorice 250g; Berberine hydrochloride 30g;

[0051] (2) the Radix Glycyrrhizae of above-mentioned formula quantity is pulverized into fine powder, for subsequent use;

[0052] (3) Decoct the iron amaranth in the amount of the above formula twice with water at 100°C, for 1.5 hours for the first time, and for 1 hour for the second time, combine the decoction, filter, and decoct at a vacuum degree of 0.08 , Concentrated at 75°C to a thick paste with a relative density of 1.20 (75°C). Add step (2) licorice fine powder to the thick paste, mix well, dry in vacuum at a low temperature of 60° C., and pulverize into 100-mesh fine powder. Combine the decoctions, filter, take the supernatant and concentrate into a thick paste, add fine powder of licorice, mix well, dry at low temperatur...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an amaranth berberine tablet and a preparation method thereof. The amaranth berberine tablet is a Chinese medicinal combined preparation comprising the following main components: copperleaf, berberine hydrochloride, liquorice, and appropriate amount of accessories. The preparation method comprises the following steps: setting the main components by the following weight percentage: 65 to 90 percent of the copperleaf, 0.5 to 10 percent of the berberine hydrochloride, and 5 to 15 percent of the liquorice; crushing the liquorice into fine powder; decocting the copperleaf in water twice, putting the decoction liquid together, filtering the mixed decoction liquid, taking the supernatant and concentrating the supernatant into thick paste, adding the liquorice fine powder, mixing the thick paste and the liquorice fine powder evenly, drying the mixture at a low temperature, crushing the mixture into fine powder, adding the berberine hydrochloride and the appropriate amount of the accessories into the fine powder, mixing the fine powder evenly with the berberine hydrochloride and the appropriate amount of the accessories, carrying out granulation and drying, adding appropriate amount of lubricant, pressing the mixture into tablets, and obtaining the finished product without coating or with a film coat. The amaranth berberine tablet consisting of the medicaments and a bulking agent, has good humidity resistance, easy carrying, quick disintegration, and small dosage.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine tablet and a manufacturing process thereof, in particular to amaranth berberine tablet and a preparation method thereof. Background technique: [0002] Diarrhea is a symptom caused by hyperactive bowel movements or decreased water absorption in the intestinal tract. It is characterized by excess moisture in the stool, which becomes less consistent and heavier, and is accompanied by more frequent bowel movements. The main reasons are: enterotoxin acts on the intestinal mucosa, bacteria directly invade the intestinal mucosa, rotavirus diarrhea, overeating or improper food ingredients, etc., the most common of which is bacterial infection and enterotoxin acts on the intestinal mucosa or bacteria directly invade the intestinal mucosa caused diarrhea. There are too many types of traditional Chinese medicines used to treat this disease, and the ingredients are too complicated. In the case of spleen a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/20A61K47/38A61P1/12A61K31/4375
Inventor 徐燕和郑施波连红徐章文
Owner FUZHOU JINXIANG CHINESE MEDICINE PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap