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A titanium implant and a process for the preparation thereof

A technology for titanium implants and implants, applied in the field of titanium implants and their preparation, can solve the problems of inability to fix, low mechanical strength and the like

Inactive Publication Date: 2009-09-23
冈纳·罗埃拉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A clinical problem is that such implants cannot be fixed by traditional methods of bonding to bone
Another problem is the low mechanical strength of ceramics

Method used

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  • A titanium implant and a process for the preparation thereof
  • A titanium implant and a process for the preparation thereof
  • A titanium implant and a process for the preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Titanium implants made of pure titanium produced in argon are blasted with diamond dust in argon until the oxide layer is removed. The implants were then transferred into a sterile 0.1 mol / l phosphate buffer solution for 4 hours or longer, followed by autoclaving and dry storage under sterile conditions.

[0076] If cooling is required during clinical procedures, a sterile 10 mmol / l pH 7.2 phosphate buffer solution should be provided for this purpose.

Embodiment 2

[0078] Titanium implants made of clinical alloys prepared by conventional methods were treated with 0.2% hydrofluoric acid aqueous solution for 30 seconds, and then directly transferred into 0.1M pH7.0 phosphate buffer solution containing 0.1% sodium pyrophosphate for 4 hours or longer. Afterwards, the implants are irradiated and stored dry in an oxygen-free and dry atmosphere.

Embodiment 3

[0080] Titanium implants were prepared under conventional conditions. The implants were grit-blasted sequentially with oxide-free titanium powder and diamond powder in argon, then moved into a saturated casein solution for 2 h, rinsed in phosphate buffered saline, and then irradiated and exposed. Store in dilute phosphate buffered saline, pH 7.

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PUM

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Abstract

The invention provides a titanium implant having increased retention after insertion in bone. The implant comprises phosphate groups bound to the metallic titanium. Also provided is a process for preparing said titanium implant, wherein the oxide layer formed on the surface of a conventional titanium implant is removed to expose the metallic titanium. The exposed implant is then treated with a phosphate solution in the absence of oxygen to bond phosphate groups to the titanium surface, said groups securing a firm attachment of the implant to the bone into which it is inserted.

Description

technical field [0001] Titanium or titanium alloys are frequently used in surgical implants, especially in connection with orthopedic surgery. These implants are biocompatible and as hard as steel. However, if exposed to atmospheric oxygen, the machined surface of titanium is covered with an oxide layer that protects the properties of the metal, thus presenting an inert surface. Background technique [0002] Titanium implants are widely used in load-bearing applications such as hip prostheses and dental implants because of their biocompatibility and mechanical strength. Direct bonding between bone and metal is rare due to the inert oxide layer covering the surface of this implant. Interestingly, although most authors believe that the oxide layer is the basis for the biocompatibility of titanium implants, a few believe that the properties of oxide-covered titanium can be improved. One approach is to apply bioactive materials on titanium implants to cover the oxide layer. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/06A61L27/32A61L27/54A61C8/00A61F2/30
CPCA61L27/06A61L31/086A61L27/32A61L31/022A61L27/047A61L2430/02
Inventor 冈纳·罗埃拉简·埃里克·埃林森
Owner 冈纳·罗埃拉