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Traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof

A technology of mammary gland hyperplasia and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of large side effects, etc., and achieve the effect of convenient portability, good curative effect, and controllable quality

Active Publication Date: 2011-08-03
SHANGHAI SHYNDEC PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a Chinese medicine composition for treating mammary gland hyperplasia and its preparation method which has the functions of regulating qi mechanism, resolving liver depression, relieving stagnation of qi, relieving pain, and eliminating lumps, so as to solve the existing problem of treating hyperplasia of mammary glands. Western medicine has many side effects, and most Chinese medicine treatments do not start with the root causes of liver and kidney deficiency and Chong Ren disorder.

Method used

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  • Traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof
  • Traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation of embodiment 1 capsule

[0023] Weigh 667g of Rhizoma Cyperi, 445g of Rhizoma Chuanxiong, 445g of Tangerine Pit, and 2000g of Centella Asiatica; distill the Radix Cyperi in 6 times of water for 5 hours, collect the volatile oil, and then wrap the volatile oil with β-cyclodextrin. Add oil-β-cyclodextrin inclusions for later use; filter the above medicinal liquid to obtain filtrate A; decoct the medicinal residue with 5 times of water for 1.5 hours, filter to obtain filtrate B, then combine filtrate A and filtrate B, and concentrate under reduced pressure to obtain Extract G with a relative density of 1.10, then add ethanol until the alcohol content is 65%, let it stand for 12 hours, and filter to obtain filtrate C; add 85% ethanol to Chuanxiong and Tangerine Pit, heat and reflux twice, add 6 times of ethanol, add 5 times of ethanol for the second time, extract for 2 hours each time, then filter, recover ethanol from the filtrate to obtain filtrate D, com...

Embodiment 2

[0025] The preparation of embodiment 2 capsules

[0026] Weigh 334g of Rhizoma Cyperi, 667g of Rhizoma Chuanxiong, 667g of Tangerine Pit, and 2445g of Centella Asiatica; distill the Rhizoma Cyperi in 7 times water for 6 hours, collect the volatile oil, and then wrap the volatile oil with β-cyclodextrin, and the aroma produced after inclusion Add oil-β-cyclodextrin inclusions for later use; filter the above medicinal liquid to obtain filtrate A; decoct the medicinal residues with 6 times of water for 2 hours, filter to obtain filtrate B, then combine filtrate A and filtrate B, and concentrate under reduced pressure to obtain Extract G with a relative density of 1.12, then add ethanol until the alcohol content is 65%, let it stand for 14 hours, and filter to obtain filtrate C; add 85% ethanol to Chuanxiong and Tangerine Pit, heat and reflux twice, add 6 times of ethanol, add 5 times of ethanol for the second time, extract for 2 hours each time, then filter, recover ethanol from ...

Embodiment 3

[0028] The preparation of embodiment 3 capsules

[0029]Weigh 889g of Rhizoma Cyperi, 334g of Rhizoma Chuanxiong, 334g of Tangerine Pit, and 1667g of Centella Asiatica; distill the Radix Cyperi in 5 times of water for 4 hours, collect the volatile oil, and then include the volatile oil with β-cyclodextrin. Add oil-β-cyclodextrin inclusions for later use; filter the above medicinal liquid to obtain filtrate A; add 4 times the water to decoct the medicinal residues for 1 hour, filter to obtain filtrate B, then combine filtrate A and filtrate B, and concentrate under reduced pressure to obtain Extract G with a relative density of 1.10, then add ethanol until the alcohol content is 65%, let it stand for 14 hours, and filter to obtain filtrate C; add 85% ethanol to Chuanxiong and Tangerine Pit and heat and reflux twice, add 6 times of ethanol, add 5 times of ethanol for the second time, extract for 2 hours each time, then filter, recover ethanol from the filtrate to obtain filtrate...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating mammary gland hyperplasia, which is prepared from the following four materials: Cyperus Rotundus L. 3-10, Ligusticum wallichii 2-8, tangerine seed 2-8 and gotu kola 10-30. The invention further discloses the preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine compositionaims the pathogenesis characteristics of the liver depression blood stasis and vital energy retardation type mammary gland hyperplasia, has the curative effects of coursing liver, rectifying qi, dissipating binds and relieving pain. The traditional Chinese medicine composition preparation in the invention achieves the characteristics of carrying and taking convenience, controllable quality and good curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating mammary gland hyperplasia and a preparation method thereof. Background technique [0002] Mammary gland hyperplasia is a non-inflammation and non-tumor proliferative lesion of breast tissue, and its clinical features are breast distending pain and breast lump. This disease is a general term for a class of diseases whose basic pathological changes are hyperplasia of epithelial cells and connective tissue in mammary acini and ducts. It belongs to the category of "breast addiction" in traditional Chinese medicine. Phlegm and blood stasis type, Chong Ren disorder type. The onset of mammary gland hyperplasia is currently considered to be related to endocrine disorders and mental factors. Excessive estrogen in the patient's body, too little progesterone, or incompatibility between the two hormones, as well as excessiv...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61P15/14
Inventor 张焱
Owner SHANGHAI SHYNDEC PHARMA CO LTD