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A device and method for the prolonged delivery of an active agent to a body cavity

An active agent, body cavity technology, applied in pharmaceutical formulations, drug devices, female contraceptives, etc., can solve the problems of prolonged recovery process, forced out of the rectum, high recurrence rate, etc.

Inactive Publication Date: 2009-10-07
大卫·博瑞沃
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Disadvantages include: 58% of treated patients report headaches, and high relapse rate
However, the central part retains the protruding shape of the device in the rectum, which causes pressing against the rectal wall, which risks facilitating defecation, which in turn will force the device out of the rectum
In addition, studies have shown that when an injury is in a moist environment and includes internal fluids and secretes active agents (pharmaceuticals), the time to the healing process is increased

Method used

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  • A device and method for the prolonged delivery of an active agent to a body cavity
  • A device and method for the prolonged delivery of an active agent to a body cavity
  • A device and method for the prolonged delivery of an active agent to a body cavity

Examples

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Effect test

Embodiment 1

[0150] Anal fissure treatment

[0151] Three patients with anal fissures were treated with an internal occlusive dressing device (hereinafter "device") according to the present invention, which was coated with tissue growth factor (TGF), fibrin generating agent and the same This therapy is formulated with natural oils selected from the group consisting of tea tree oil, calendula oil, propolis extract and aqueous witch hazel flower extract. A case study is reported below.

[0152] Case Study #1

[0153] A 33-year-old woman, shortly after delivery, complained of recurrent painful episodes and bloody bowel movements attributed to anal fissures and constipation. The patient had previously been treated with a number of treatments, including steroid creams, nitroglycerin sprays, "Zitz" baths, and a special diet. The patient also resorted to other medications. When first examined, the patient appeared very anxious, panicked and distressed. Anal examination revealed that the anal...

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Abstract

A device for application to a body cavity. The device is insertable into the cavity of a subject in need. The device includes a non-absorbable, flexible tube of an elongated shape, a removable core element situation within the tube, and a retention mechanism for maintaining the device within the cavity.

Description

technical field [0001] The present invention generally relates to a device and method for the sustained release of an active agent into a body cavity. The sustained release device and method can be used for local treatment or systemic treatment. Background technique [0002] The publications and other references referred to herein, including the references used herein, are hereby incorporated in their entirety and are hereinafter indexed by number, respectively, in the Appendix's Bibliography of References, in the claims Before. [0003] There are many situations in which it is desirable to deliver an active agent to a body cavity. A prime example of such a situation is the case of rectal disorders, especially anal fissures. [0004] Although not widely known, people often visit their physician for reasons related to rectal conditions. An example of a common disorder that occurs in both sexes, young and old, is anal fissure [1,2]. Anal fissure (hereinafter abbreviated a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M31/00
CPCA61M25/04A61M31/002A61K9/0031A61F6/08
Inventor 大卫·博瑞沃
Owner 大卫·博瑞沃