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Tangerine peel buccal tablets, oral disintegrating tablets and application thereof

A technology of orally disintegrating tablets and buccal tablets, which is applied to medical preparations containing active ingredients, pill delivery, plant raw materials, etc., can solve problems such as unstable effects, inconvenient medication, and insignificant effects

Inactive Publication Date: 2010-02-24
詹晓如 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also some folk remedies used to prevent motion sickness, but the effect of these methods is unstable, insignificant, or inconvenient to use

Method used

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  • Tangerine peel buccal tablets, oral disintegrating tablets and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1: a kind of tangerine peel buccal tablet, composition is as follows:

[0050] Chenpi 173.0g

[0051] 346.0 grams of fresh ginger

[0052] Powdered sugar 20 0.8g

[0053] Soluble starch 200.8g

[0054] Citric acid 16.0g

[0055] Aspartame 6.0g

[0056] Orange essence 3.0g

[0057] Magnesium Stearate Appropriate amount

[0058] Weigh each component according to the above formula. Add an appropriate amount of water to decoct the tangerine peel medicinal material twice, each time for 2 hours, combine the decoction and filter, concentrate the filtrate into a thick paste (relative density at 60°C 1.0-1.10); extract volatile oil from ginger, filter the distilled aqueous solution, and filter the filtrate Concentrate into thick paste (relative density 1.0-1.10 at 60°C); combine tangerine peel thick paste and ginger thick paste, dry, and grind into fine powder; add 200.8 grams of powdered sugar, 200.8 grams of soluble starch, 16 grams of citric acid, and aspart...

Embodiment 9

[0062] Embodiment 9: a kind of tangerine peel orally disintegrating tablet, its composition is as follows:

[0063] Chenpi 173.0g

[0064] Ginger 346.0g

[0065] Microcrystalline Cellulose 154.0g

[0066] Crospovidone 46.1g

[0067] Low-substituted hydroxypropyl cellulose 39.2g

[0068]Mannitol 51.2g

[0069] Citric acid 39.2g

[0070] Sodium bicarbonate 39.2g

[0071] Aspartame 5.12g

[0072] Micronized silica gel 10.2g

[0073] 5% Povidone K 30 Proper amount of absolute ethanol solution

[0074] A total of 1000 pieces were made

[0075] Weigh each component according to the above formula. Add an appropriate amount of water to decoct the tangerine peel medicinal material twice, each time for 2 hours, combine the decoction and filter, concentrate the filtrate into a thick paste (relative density at 60°C 1.0-1.10); extract volatile oil from ginger, filter the distilled aqueous solution, and filter the filtrate Concentrate into thick paste (relative density 1.0-1.10 ...

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Abstract

The invention relates to tangerine peel buccal tablets, oral disintegrating tablets and application thereof. 1,000 tangerine peel buccal tablets or 1,000 oral disintegrating tablets are prepared fromthe following components and pharmaceutically acceptable additives: 120 to 220 grams of tangerine peel and 380 to 480 grams of fresh ginger. The tangerine peel has bidirectional regulation function ongastrointestinal smooth muscles so as to influence the gastrointestinal motility; the ginger can inhibit the central nervous system to release vasopressin so as to relive electrogastric hypsarrhythmia in motion sickness and symptoms such as nausea, vomit and the like; and when the tangerine peel and the ginger are combined, the effect of the combination is superior to that of dimenhydrinate, andthe combination has no adverse reaction such as drowsiness, dizziness, headache, thirst, nausea, vomit, epigastric region discomfort and the like.

Description

technical field [0001] The invention relates to a tangerine peel buccal tablet, an orally disintegrating tablet and applications thereof. Background technique [0002] Tangerine peel comes from the mature peels of rue plants Citrus, reticulata, Blanco and their cultivars. Li Shizhen in the Ming Dynasty said: "Tonic is tonic, laxative is tonic, medicine to ascend is to rise, medicine to fall is to fall. Spleen is the original qi. The mother of the herb, the lung is the sign for the uptake of qi, so the orange peel is the medicine for the two meridian qi, but it can also nourish, relieve and ascend according to the composition." Therefore, tangerine peel preparations are widely used in the treatment of diseases such as respiratory tract and digestive tract. In recent years, tangerine peel preparations also have a good effect on cardiovascular, endocrine, anti-cancer, anti-aging, beauty, nutrition and tonic. [0003] The dosage forms of tangerine peel preparations mainly incl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/20A61P1/08
Inventor 詹晓如容振勤郑小吉王小平
Owner 詹晓如
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