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A medicinal preparation for treating breast cancer and preparation method thereof

A pharmaceutical preparation and breast cancer technology, applied in the field of traditional Chinese medicine preparations for breast cancer and its preparation, can solve problems such as inconvenient taking, achieve the effects of taking conveniently, improving the quality of life, and reducing adverse events

Inactive Publication Date: 2012-09-12
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine decoction needs to be decocted every day, which has the disadvantage of being inconvenient to take

Method used

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  • A medicinal preparation for treating breast cancer and preparation method thereof
  • A medicinal preparation for treating breast cancer and preparation method thereof
  • A medicinal preparation for treating breast cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1 part of Astragalus, 1 part of Codonopsis pilosula, 1 part of Atractylodes macrocephala, 1 part of medlar, 1 part of Nansha ginseng, 1 part of fairy spleen, 1 part of dogwood,

[0020] Take half of the amount of medicine in the above formula, add 3 times the amount of water, soak for half an hour, decoct for 45 minutes, add 3 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilize, irradiate at a dose of 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, mix well and use 60% ethanol as a binder to make granules. The granular preparation is 10g / bag.

Embodiment 2

[0022] 3 parts of Astragalus, 2 parts of Codonopsis, 2 parts of Atractylodes macrocephala, 2 parts of Lycium barbarum, 2 parts of Nansha ginseng, 2 parts of Xianling spleen, 2 parts of Cornus officinalis, and the rest are medicinal excipients.

[0023] Take half of the amount of medicine in the above formula, add 8 times the amount of water, soak for half an hour, decoct for 45 minutes, add 8 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilization, irradiation dose 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, after mixing uniformly, use 70% ethanol as binding agent to make granule; According to conventional method, Add molding excipients or flavoring excipients to make tablets.

Embodiment 3

[0025] 3 parts of Astragalus, 2 parts of Codonopsis pilosula, 2 parts of Atractylodes macrocephala, 2 parts of medlar, 2 parts of Nansha ginseng, 1 part of fairy spleen, 1 part of dogwood, and the rest are medicinal excipients.

[0026] Take half of the amount of medicine in the above formula, add 8 times the amount of water, soak for half an hour, decoct for 45 minutes, add 8 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain dry extract , crushed into fine powder (over 80 mesh). The other half of the crude drug was crushed to 80 mesh, and the 60 Sterilization irradiation dose 8k, mix with extract powder, add mannitol, lactose, sucrose powder, aspartame, menthol, mix well and use 70% ethanol as binder to make granules.

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Abstract

The present invention belongs to the field of traditional Chinese pharmaceutics, which relates to a traditional Chinese medicinal preparation for treating breast cancer and preparation method thereof. The present invention adopts supplementing qi, nourishing yin, regulating the thoroughfare and controlling vessels as therapeutic principle, which adopts the extracts of the following traditional Chinese medicine raw materials: radix astragali, Radix Codonopsis, bighead atractylodes rhizome, wolfberry, adenophora tetraphylla, epimedium sagittatum, Cornus officinalis, and auxiliary material to prepare a small preparation for treating breast cancer. By animal experiment and clinic trial, the results show that the preparation particles of the present invention can inhibit tumor growth and lung metastasis of tumor-bearing mice and enhance body antitumor enhance host anti-tumor immunity; the clinical studies showed that preparation particles of the present invention can obviously decrease side effects caused by a medicament for treating breast cancer and auxiliary treating endocrine, reduce adverse event, improve depression, and anxiety symptoms, and improve life quality of patient. The preparation of the present invention has the advantages of convenient administration, little dosage, no toxic side effect even long-term administration, and good evaluation.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for treating breast cancer and a preparation method thereof. Background technique: [0002] According to reports, the incidence of breast cancer ranks first among female malignant tumors, and it is one of the most common malignant tumors that threaten women's health. Statistics in the United States in 2000 showed that the incidence of breast cancer accounted for 30% of all malignant tumors, ranking first, and the mortality rate accounted for 15%, ranking second. Relevant surveys show that the incidence of breast cancer in China has a clear upward trend in recent years, with an estimated annual incidence of 120,000. In 2005, the incidence of breast cancer in Shanghai reached 57 / 100,000. [0003] With the renewal of health concepts and the establishment of new medical models, the improvement and improvement of the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61K9/00A61K9/16A61K9/20A61K9/48A61P35/00
Inventor 万华吴雪卿冯佳梅傅勤慧高晴倩李欣荣瞿文超陶颖娜
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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