Compound preparation for treating cold and preparation method thereof

Abstract

The invention relates to a compound preparation for treating cold and a preparation method thereof, belonging to the technical field of medicines. The compound preparation contains a sustained-releasedosage form prepared by respectively selecting an ingredient from an adrenomimetic drug and an antipyretic-analgesic and anti-inflammatory drug, and a fast-release membranous layer formed by any ingredient of an antihistamine drug, wherein the membranous layer is coated on the sustained-release dosage form, the antihistamine drug has fast effect and long time of drug effect, better treating effect can be achieved by fast release of the fast-release membranous layer, and simultaneously, the constant drug level of the adrenomimetic drug and the antipyretic-analgesic and anti-inflammatory drug is maintained in blood by sustained-release releasing. Therefore, the compound preparation can overcome the symptoms related to the cold, including the symptoms of nasal obstruction, sneeze, nasal bleeding, sputum itching, lacrimation and the like with pain and fever.

Description

technical field [0001] The invention relates to a medicinal compound preparation and a preparation method thereof, in particular to a medicinal compound preparation for treating colds and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Influenza is the most common multiple disease of human beings, and it is a respiratory infectious disease that seriously endangers human health. According to statistics, adults suffer from 3 to 4 colds per year, and children have as many as 6 or more. The clinical manifestations of influenza can be divided into simple type, pneumonia type, poisoning type and gastrointestinal type, and can cause various complications. , the hazard is serious. [0003] my country is a cold-prone area, and there are outbreaks or epidemics in some areas almost every year, and its incidence rate ranks first in infectious diseases. Influenza viruses are easy to mutate and form new strains, which brings gre...

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Problems solved by technology

[0005] As we all know, the preparation quality of a drug will greatly affect the clinical application value of the drug. No matter what kind of preparation, the blood drug concentration after entering the body must be within the therapeutic window to exert a normal therapeutic effect. produce toxic side effects

It has been found through research that for drugs with a short half-life, large doses of drugs must be administered multiple times in clinical practice to achieve the therapeutic purpose, which not only causes "peak-valley" fluctuations in blood drug concentration, but also brings great trouble to patients. It is easy to miss doses and the interval between taking medicine at night is too long to maintain effective blood drug concentration and exert a continuous therapeutic effect. There is a blind spot in curative effect, and there is instability in clinical curative effect. It is developed as a slow-release drug that is taken less frequently. Dosage forms can overcome the above deficiencies, and for drugs that act quickly and maintain long-lasting effects, they only need to be made into immediate-release dosage forms

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