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A traditional Chinese medicine composition for treating gastrointestinal diseases and its preparation method

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as harm to fetal and infant health, endocrine system harm, mercury harm, etc.

Active Publication Date: 2015-07-29
TIANJIN ZHONGXIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its formula contains cinnabar, its function is to calm the nerves, but cinnabar contains mercury, which is very harmful to the human body. It is a subtle and continuous absorption process. Long-term exposure to mercury will cause chronic poisoning: Harmful to human nerves, digestion, endocrine system and kidneys; people with neurasthenia may cause symptoms such as headache, dizziness, insomnia, memory loss, and general fatigue; and long-term exposure to mercury by pregnant and breastfeeding women may also harm the fetus and baby's health
In addition, mercury-containing medicines are subject to certain restrictions when exported to other countries. For example, Singapore requires that the mercury content must be less than 0.5ppm, while the requirements for some European countries are more stringent.

Method used

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  • A traditional Chinese medicine composition for treating gastrointestinal diseases and its preparation method
  • A traditional Chinese medicine composition for treating gastrointestinal diseases and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0118] a. Take the following raw materials by weight: 150g of clove, 150g of agarwood, 150g of citrus aurantii, 90g of sandalwood, 90g of rhubarb, 150g of Magnolia officinalis, 4.5g of artificial musk, 60g of croton cream, 500g of jujube, and 90g of chuanxiong for later use;

[0119] b. The above ten herbs, croton cream and musk are crushed into fine powder for later use; 2 Supercritical extraction; take the extract, add an appropriate amount of absolute ethanol to dissolve, add an appropriate amount of β-CD for clathrate, and dry to obtain the clathrate for later use; ethanol extract the dregs of the above supercritical extract twice, combine Take the filtrate twice, recover the ethanol and concentrate it for later use; take the jujube and add water to decoct it twice, and filter; combine the filtrate, concentrate, mix with the above-mentioned alcohol extract concentrate, dry, grind into fine powder, and then mix with clathrate, croton Cream and musk are sieved and mixed, sie...

Embodiment 2

[0121] a. Get the following raw materials by weight: clove 100g, agarwood 600g, citrus aurantii 600g, sandalwood 360g, rhubarb 360g, magnolia officinalis 600g, musk 18g, croton cream 240g, jujube 2000g, chuanxiong 360g for later use;

[0122] b. Top ten medicines, croton cream and musk are crushed into fine powder for later use; six medicines such as clove, agarwood, sandalwood, citrus aurantii, magnolia officinalis, and Chuanxiong are crushed into coarse powder, added with water, soaked, decocted and distilled, and collected volatile oil , after inclusion with β-CD, set aside; filter the decoction, concentrate the filtrate for later use, extract the dregs and rhubarb coarse powder with ethanol for 2 times, and filter; combine the second filtrate, concentrate, dry, and set aside; take jujube, add Decoct twice with water, filter; combine the second filtrate, concentrate, dry, dry and pulverize into fine powder, mix with croton cream and musk, and set aside; prepare granules acco...

Embodiment 3

[0124] a. Get the following raw materials by weight: 200g clove, 150g agarwood, 600g citrus aurantii, 360g sandalwood, 90g rhubarb, 200g magnolia officinalis, 10g musk, 80g croton cream, 1500g jujube, 300g chuanxiong for later use;

[0125] b. The above ten flavors, croton cream and musk are crushed into fine powder respectively; the remaining cloves, agarwood and other eight flavors are decocted with water for 2 times, each time for 2 hours, and the decoctions are combined, filtered, concentrated into a thick paste, and poured into the above thick Add croton cream and musk powder to the ointment, mix well, and set aside; take an appropriate amount of polyethylene glycol 6000, heat to melt, add the above-mentioned thick ointment, croton cream, and musk powder mixture, mix well, and adopt a dripping speed of 85-90 drops / min, drop into cooled liquid paraffin to make drop pills, that is to say.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Diarrhea can be divided into infectious and non-infectious categories. Infectious diarrhea is divided into bacterial infection and viral infection; non-infectious diarrhea can be caused by various reasons such as improper diet, food allergies, changes in life patterns, sudden changes in climate, and even emotional stress. Traditional Chinese medicine believes that diarrhea refers to increased frequency of defecation, clear and thin stool, or even watery. The main lesion of diarrhea lies in the spleen, stomach and large and small intestine. The causes of the disease include exogenous evils, injury from diet, disharmony of the seven emotions, internal resistance of dampness, and weakness of viscera. The pathogenicity of dampness seen clinically...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/835A61P1/00A61P1/08A61P1/12A61P1/14A61K31/122
CPCY02A50/30
Inventor 陈坚王磊袁学海王伟杨瑾王春晨郝忻
Owner TIANJIN ZHONGXIN PHARMA GRP CO LTD