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Combination for repairing dental enamel and method for preparing fluorapatite by using the same

A technology of fluoroapatite and its composition, which is applied in the field of biomaterials for dental restoration, can solve the problems of filling body fracture and detachment, secondary caries, etc., and achieve the effect of high chemical stability

Inactive Publication Date: 2010-09-29
PEKING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This restoration method can restore the shape and function of the tooth tissue in the short term, but due to the shrinkage and aging of the material, secondary caries often occurs in the long term, or the filling body breaks and falls off.
However, for enamel caries that are not suitable for cavity preparation in the early stage, or some carious lesions that cannot obtain resistance or retention, it is not suitable to use the above materials for filling

Method used

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  • Combination for repairing dental enamel and method for preparing fluorapatite by using the same
  • Combination for repairing dental enamel and method for preparing fluorapatite by using the same
  • Combination for repairing dental enamel and method for preparing fluorapatite by using the same

Examples

Experimental program
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Effect test

example 1

[0027] Mix 2.66 grams of tetracalcium phosphate and 1.36 grams of calcium hydrogen phosphate powder evenly, then add 0.4 grams of sodium fluoride to the mixed powder, mix evenly in the mixing pan, add 4 mL of water to the mixed powder of the three substances, and use a key to blend into cement The slurry was further reconciled into a jelly-like substance, and it was placed in a 37°C, 100% humidity environment for 3 days. The obtained material was fluorapatite. Its chemical structure and composition were characterized by XRD, IR and EDS. The results are as follows Figure 1-Figure 3 shown. It can be seen from the XRD pattern that the prepared product has its characteristic peaks around 2θ=26°, 2θ=32°, 2θ=34°, 2θ=40°, 2θ=47°, and 2θ=50°. The results show that the synthesized product is fluorapatite. It can be seen from the IR spectrum: at 1070cm -1 and 950cm -1 PO 4 3- the absorption peak. at 1432 and 1750.8cm -1 Two absorption peaks at and from 2800cm -1 to 3472cm -1 T...

example 2

[0029] Mix 1.33g of tetracalcium phosphate and 0.68g of calcium hydrogen phosphate powder evenly, then add 0.2g of sodium fluoride to the mixed powder, mix evenly in the mixing pan, add 2mL of water to the mixed powder of the three substances, and use a key to blend into cement The slurry was further reconciled into a jelly-like substance, which was filled into the carious enamel defect, and the tooth was placed in a 37°C, 100% humidity environment for 3 days to obtain an experimental sample. Use SEM to characterize the microstructure of the material surface, such as Figure 4 shown. From the SEM photo, it can be seen that fluoroapatite and enamel form a tight bond, and there is no obvious gap on the interface, which can also indicate that the restorative material fluoroapatite and enamel have similar components, making them easy to bond together. Synthetic fluoroapatite is needle-like crystals that are tightly bound together. Cut the material together with the tooth from t...

example 3

[0031]Mix 26.6 grams of tetracalcium phosphate and 13.6 grams of calcium hydrogen phosphate powder evenly with a star ball mill, add 4 grams of sodium fluoride into water to form a solution, add the mixed powder of tetracalcium phosphate and calcium hydrogen phosphate to 40mL of water, and mix with a key Form cement slurry, further reconcile into gel substance, fill it into carious tooth enamel defect, put the tooth in 35~38 ℃, 100% humidity environment for 3 days, get the test sample.

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Abstract

The invention discloses a combination for repairing damaged dental enamel, belonging to the field of dental repairing biomaterials. The method comprises steps that tetracalcium phosphate, calcium hydrophosphate and sodium fluoride are mixed, water is added for blending to form cement-like substances, the cement-like substances are filled in carious cavities of carious teeth with damaged enamel, the cement-like substances are cured for 1-3 days under a human body physiological environment to generate fluorapatite, and thereby the carious damaged enamel, especially large damaged enamel (deep caries) can be repaired. Since the synthesized fluorapatite has chemical components similar to the chemical components of the dental enamel, repairing materials can be directly combined with natural dental enamel. The synthesized fluorapatite has a stoichiometric phosphorite structure, the chemical stability under the condition of human physiological body liquid is very high (i.e. the dissolubility is low), fluorions are slowly released under the acidic condition (the existence of bacteria), and thereby the anticarious efficacy is obtained.

Description

technical field [0001] The invention belongs to the field of biological materials for dental restoration, and in particular relates to a medical material for repairing carious tooth enamel defect. Background technique [0002] Dental caries (dental caries) is a progressive lesion of dental hard tissue caused by the compound action of various factors in the oral cavity. It is the main common disease of the oral cavity, and it is characterized by high incidence and wide distribution. The World Health Organization has listed it together with cancer and cardiovascular disease as the three major human diseases. According to the national oral epidemiological survey report, the prevalence rate of dental caries among Chinese residents is 50%, and that of deciduous teeth is 80%. According to survey statistics, the total number of caries in my country is as high as more than 2 billion, and more than 90% of these caries have not received treatment. Recent survey data in the United St...

Claims

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Application Information

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IPC IPC(8): A61K6/033A61K6/027C01B25/32A61K6/838
Inventor 魏世成魏杰刘晓晨王成洁张翼飞
Owner PEKING UNIV
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