Medicinal composition and preparation for strengthening bones and preparation method thereof

A technology of composition and efficacy, applied in the field of preparation of the pharmaceutical preparation, can solve the problems of high probability of side effects, high cost, complicated preparation process, etc., and achieve the effects of improving bone quality, promoting synthesis, and low cost

Inactive Publication Date: 2011-02-09
林晨伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its disadvantages are that there are too many medicinal flavors, the preparation process is complicated, the probability of side effects is high, and the cost of long-term use is relatively high.

Method used

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  • Medicinal composition and preparation for strengthening bones and preparation method thereof
  • Medicinal composition and preparation for strengthening bones and preparation method thereof
  • Medicinal composition and preparation for strengthening bones and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041]Preparation of Eucommia ulmoides extract in the pharmaceutical composition of the present invention:

[0042] The preparation method of Eucommia ulmoides extract is as follows: decoct 60 g of Eucommia ulmoides with water for three times, add 10 times of water each time and decoct for 1 hour, filter and combine the filtrate extracted three times, concentrate under reduced pressure; add 95% ethanol to the concentrated solution to make alcohol-containing The amount is 60%, let it stand, filter, collect the filtrate, recover ethanol until it has no alcohol smell, concentrate and dry under reduced pressure to obtain a dry extract for future use.

Embodiment 1

[0043] The preparation of embodiment 1 pharmaceutical capsule of the present invention

[0044] Raw material and dosage:

[0045] Calcium citrate 44g, glucosamine 45g, Eucommia extract 9g, soybean isoflavone 1g, chondroitin sulfate 1g, vitamin D 0.001g.

[0046] Preparation:

[0047] (1) Take the crude drug by weighing the above-mentioned proportioning by weight;

[0048] (2) Mix Eucommia ulmoides extract, soybean isoflavones, glucosamine, chondroitin sulfate and calcium citrate evenly, and pass through the 80-mesh sieve to obtain the medicinal powder for subsequent use after crushing;

[0049] (3) Dissolving and diluting vitamin D with 95% ethanol, evenly adding to the above-mentioned medicinal powder, adding ethanol to granulate, drying, and forming a whole;

[0050] (4) Before the calcium citrate is mixed with Eucommia extract and soybean isoflavones, it is first pulverized, passed through a 120 mesh sieve, dried and sterilized to obtain the active ingredient;

[0051] ...

Embodiment 2

[0052] Embodiment 2 capsule preparation of the present invention

[0053] Raw material and dosage:

[0054] Calcium citrate 35g, glucosamine 55g, Eucommia extract 5g, soybean isoflavone 3g, chondroitin sulfate 2g, vitamin D 0.005g.

[0055] Preparation:

[0056] (1) Take the crude drug by weighing the above-mentioned proportioning by weight;

[0057] (2) Mix Eucommia ulmoides extract, soybean isoflavones, glucosamine, chondroitin sulfate and calcium citrate evenly, and pass through the 80-mesh sieve to obtain the medicinal powder for subsequent use after crushing;

[0058] (3) Dissolving and diluting vitamin D with 95% ethanol, evenly adding to the above-mentioned medicinal powder, adding ethanol to granulate, drying, and forming a whole;

[0059] (4) Before the calcium citrate is mixed with Eucommia extract and soybean isoflavones, it is first pulverized, passed through a 120 mesh sieve, dried and sterilized to obtain the active ingredient;

[0060] (5) Capsules are prepa...

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Abstract

The invention relates to a medicinal composition for strengthening bones, which is prepared from the following raw materials in part by weight: 35 to 50 parts of calcium citrate, 35 to 55 parts of glucosamine, 5 to 10 weight parts of eucommia bark extract, 1 to 3 parts of soy isoflavones, 1 to 5 parts of chondroitin sulfate and 0.001 to 0.008 part of vitamin D. The medicinal composition is based on a strict formula and has a special and remarkable effect; the raw materials of the medicinal composition are widely available; and the cost of the medicinal composition is low. The simplicity of the formula makes medicament quality control simple. The components are combined to produce a synergetic effect for tonifying liver and kidney, supplementing calcium, strengthening bones and relieving pain in bone joints and consequently for increasing bone density, preventing and treating osteoporosis, promoting synthesis of bone collagen and proteoglycan, retaining damaged joints and bones and strengthening muscles and bones. The medicinal composition increases bone density, prevents osteoporosis and relieves pain in bone joints by exerting influences on the systems and organs of the body and regulating the links and factors associated with bone and joint metabolism.

Description

technical field [0001] The invention relates to a pharmaceutical composition, specifically a pharmaceutical composition for osteoporosis, and a pharmaceutical preparation prepared by using the composition. The invention also relates to a preparation method of the pharmaceutical preparation. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by low bone mass and microstructural destruction of tissues, leading to bone fragility and increased risk of fracture. Clinically, it often manifests as pain, shortened body length, hunched back and easy fractures, etc. Among them, low back pain is the most common, and fracture is the most serious complication. Primary osteoporosis is the degenerative disease of the skeletal system caused by the overall aging of the human body. Decreased bone density is the result of thick-onset osteoporosis. One of the main manifestations of the disease. Bone mineral density is also often used as the cornerstone of o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61P19/08A61P19/10A61K31/7008A61P19/02A61K31/737A61K36/46A61K31/352A61K31/194
Inventor 林晨伟金道山朱庆磊
Owner 林晨伟
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