Bacterial culture fermentation tank device and fermentation technology thereof

A technology of bacterial culture and fermenter, applied in bacteria, bioreactor/fermenter combination, specific-purpose bioreactor/fermenter, etc., can solve problems affecting the smooth progress of bacterial culture and fermentation, imperfect disinfection system, air Incomplete filtration and other problems, to achieve good sterilization effect, no bacteria interference, fast heating effect

Active Publication Date: 2011-02-16
兆丰华生物科技(南京)有限公司 +1
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  • Abstract
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Problems solved by technology

[0003] At present, the fermentation tank device is generally used for bacterial culture. This device usually includes a control system, which can realize automatic adjustment and control. There are technical problems of unclean cleaning and incomplete disinfection, incomplete air filtration with bacteria, and poor insulation effect during the fermentation process, which greatly affects the smooth progress of bacterial culture and fermentation

Method used

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  • Bacterial culture fermentation tank device and fermentation technology thereof
  • Bacterial culture fermentation tank device and fermentation technology thereof
  • Bacterial culture fermentation tank device and fermentation technology thereof

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Embodiment Construction

[0024] The present invention will be further described below in conjunction with the accompanying drawings.

[0025] Reference attached figure 1 , a bacterial culture fermentation tank device, comprising a fermentation tank 2 with a stirring paddle 1, a jacket 3 is arranged outside the fermentation tank 2, and it is characterized in that: the top of the fermentation tank 2 is provided with a cleaning and disinfection injection pipe 4, a feeding pipe 5 and the air input pipe 6, the fermentor 2 is controlled by a PLC controller 7, and the input end of the PLC controller 7 is connected with a temperature sensor 8, a pH value sensor 9, a dissolved oxygen value sensor 10 and a stirring tank that are arranged in the tank body. The speed sensor 11 is connected, the temperature sensor 8 controls the hot water tank through the PLC controller 7 to control the temperature of the jacket circulating hot water, and the pH value sensor 9 controls the acid solution 14 and the lye through the ...

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Abstract

The invention relates to a bacterial culture fermentation tank device and a fermentation technology thereof. The bacterial culture fermentation tank device is characterized in that the top of the fermentation tank is provided with a cleaning and disinfecting charging tube, a feeding tube and an air input tube; the fermentation tank is controlled by a PLC controller, and the input end of the PLC controller is connected with a temperature sensor, a pH value sensor, a dissolved oxygen value sensor and a stirring speed sensor which are arranged in the tank body; the lower side of the fermentationtank body is provided with a dumping tube; the cleaning and disinfecting charging tube is communicated with a pure steam input tube, an input tube of water for injection, an acid-base lotion input tube, a purified water input tube and a drinking water input tube, wherein the bypass direction of the pure steam input tube is provided with the air intake tube of the air filter; and the air intake tube extends to the bottom of the fermentation tank. The device has good online cleaning, online sterilization and heat preservation effect and is favourable for culturing and fermenting bacteria.

Description

technical field [0001] The invention relates to a bacteria culture and fermentation device, in particular to a bacteria culture and fermentation tank device and a fermentation process thereof. Background technique [0002] Fermentation engineering consists of three parts: upstream engineering, midstream engineering and downstream engineering. Among them, the upstream project includes the selection of excellent seed strains, the determination of the optimum fermentation conditions (pH, temperature, dissolved oxygen and nutrient composition), the preparation of nutrients, etc. Midstream engineering mainly refers to the process technology of cultivating cells in large quantities and producing metabolites in fermentors under optimal fermentation conditions. There must be a strict aseptic growth environment here, including the technology of using high temperature and high pressure to sterilize the fermentation raw materials, fermentation tanks and various connecting pipes before...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/07C12M1/34C12M1/02C12M1/04C12M1/36C12N1/20C12M1/00
CPCC12M39/00C12M41/42C12M41/26C12M41/12C12M41/48C12M37/00
Inventor 陈先进吴润生林拱阳
Owner 兆丰华生物科技(南京)有限公司
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