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Specimen preserving, fixing and accelerating agent

A technology of accelerators and specimens, which is applied in the fields of botanical equipment and methods, preservation of human or animal bodies, and plant preservation, etc. The effect of reducing the time it takes to fix

Active Publication Date: 2013-01-30
无锡市江原实业技贸有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The environment-friendly non-formalin fixative adopts the natural sedimentation fixation mechanism, and the penetration rate in tissue specimens is lower than that of formalin, resulting in a longer fixation time than formalin, which brings inconvenience to the wide use of hospital pathology departments

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The weight percentage composition of the specimen antiseptic fixation promoter is 2% lauryl azone, disodium ethylenediaminetetraacetic acid (EDTA-2Na) 0.2%, and the rest is an ethanol solution with a concentration of 50vt%. In the tissue specimen fixation test, the fixation speed without the fixation accelerator is 5mm / 10 hours, and the fixation speed after adding the fixation accelerator is 5.6mm / 10 hours, and the fixation speed is increased by 12%.

Embodiment 2

[0026] The weight percentage composition of the specimen antiseptic fixation accelerator is 10 azone, disodium ethylenediaminetetraacetic acid (EDTA-2Na) 5%, and the rest is an ethanol solution with a concentration of 50vt%. In the tissue specimen fixation test, the fixation speed without the fixation accelerator is 5mm / 10 hours, and the fixation speed after adding the fixation accelerator is 6.5mm / 10 hours, and the fixation speed is increased by 30%.

Embodiment 3

[0028] The weight percentage composition of the preservative and fixation promoter of the specimen is 5% thiophene, 0.2% ethylenediaminetetraacetic acid tetrasodium salt (EDTA-4Na), and the rest is an ethanol solution with a concentration of 50vt%. In the tissue specimen fixation test, the fixation speed without the fixation accelerator is 5mm / 10 hours, and the fixation speed after adding the fixation accelerator is 5.7mm / 10 hours, and the fixation speed is increased by 14%.

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PUM

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Abstract

The invention discloses a specimen preserving, fixing and accelerating agent which comprises the following components in percentage by weight: 2-20% of main additive, 0.2-5% of auxiliary additive and the balance of ethanol solution of which the concentration is 50vt%, wherein the main additive is selected from laurocapram, thiazone, menthol or isopropyl myristate; and the auxiliary additive is selected from disodium ethylene diamine tetraacetate, ethylene diamine tetraacetic acid tetrasodium salt, ethylene diamine tetraacetic acid dipotassium salt, ethylene diamine tetraacetic acid tripotassium salt, ethylene diamine tetraacetic acid calcium disodium salt or ethylene diamine tetraacetic acid zinc disodium salt. The specimen preserving, fixing and accelerating agent can effectively improve the velocity of permeability of an environment-friendly non-formalin fixing solution in human bodies, animals and plant tissues, shorten the fixing time, and improve the efficiency and the quality for manufacturing pathological sections by a pathology department.

Description

Technical field [0001] The invention relates to the technical field of anticorrosion, in particular to a specimen anticorrosive fixation accelerator. Background technique [0002] Formalin (formalin, dilute formaldehyde solution) is the most commonly used preservative for human, animal, and plant tissue specimens. The formaldehyde in formalin can bind to the amino group of protein, and the protein is irreversible. It is used in humans, animals, and plants. The preservation of tissue specimens has a history of more than 100 years. In the hospital pathology department and surgical operating room, formalin is used to fix pathological tissue specimens to prevent tissue autolysis, structural destruction, and cell deformation. After the tissue specimens are in vitro, they are fixed with fixative to make pathological sections for medical treatment. Pathological diagnosis. Medical pathological diagnosis requires high-quality pathological slices, and correct specimen fixation is the fir...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N1/00A01N3/00
Inventor 谢敏浩吴军戴军邹霈刘娅灵何拥军王洪勇吴昊
Owner 无锡市江原实业技贸有限公司