Application of t-2 toxin in preparation of medicine for treating brain tumors

A T-2, brain tumor technology, applied in the direction of anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., can solve the undiscovered problems of T-2 toxin research
CN101984962BActive Publication Date: 2011-12-07SHENZHEN ICARBONX INTELLIGENT PEPTIDE PHARM TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHENZHEN ICARBONX INTELLIGENT PEPTIDE PHARM TECH CO LTD
Publication Date
2011-12-07

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Abstract

The invention discloses a new application of T-2 toxin, that is, the application of T-2 toxin in the preparation of medicines for treating brain tumors. The effective therapeutic dose is 0.1-20 mg / Kg body weight, preferably 0.5-8 mg / Kg body weight The administration may be implantation administration, oral administration, intravenous injection administration, subcutaneous injection administration, intramuscular injection administration, preferably intratumoral injection. The inventors of the present application established various solid tumor models, and then injected T-2 toxin into the tumor or co-cultured with cells to investigate the inhibitory effect of T-2 toxin on tumor or tumor cells. Experiments have shown that intratumoral injection has a definite curative effect on tumors, especially solid tumors that are difficult to remove, and intratumoral injection can further reduce the scope and degree of side effects of T-2 toxin, reduce its side effects and improve the efficacy of T-2 toxin. Inhibition and killing of tumor tissue.
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Description

technical field

[0001] The invention relates to the application of T-2 toxin in the preparation of medicine for treating brain tumors. Background technique

[0002] Tumor is one of the common diseases that threaten human health, second only to cardiovascular disease. The research on tumor has made great progress, and a variety of radiotherapy, chemotherapy and other methods have been developed to treat tumors. However, various drugs and therapies There are limitations, it is difficult to achieve a radical effect, and prone to drug resistance and side effects. The mortality rate of cancer still ranks first in various diseases. According to statistics, in 2006, 3 million people died of cancer in my country, and the incidence of cancer is still on the rise, and there is a trend of getting younger. According to statistics, in less than 20 years, the incidence of cancer in my country has increased by 69%, and the mortality rate has increased by 29.4%. Therefore, the study of n...

Claims

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