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Percutaneous absorption film coating agent for treating rheumatoid arthritis and preparation method thereof

A technology for rheumatoid and arthritis, applied in the field of pharmaceutical preparations, can solve the problems of no coating agent and no preparation method, and achieve the effects of simple preparation method, convenient use and low investment

Inactive Publication Date: 2011-03-30
FUJIAN ACAD OF MEDICAL SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, there are many research reports and patents about coating agents, but there is n

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  • Percutaneous absorption film coating agent for treating rheumatoid arthritis and preparation method thereof
  • Percutaneous absorption film coating agent for treating rheumatoid arthritis and preparation method thereof

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Abstract

The invention relates to a percutaneous absorption film coating agent for treating rheumatoid arthritis and a preparation method thereof. The film coating agent comprises main drugs for treating the rheumatoid arthritis, a drug solvent, a binding agent, a film forming agent and a percutaneous absorption penetration enhancer. The main drugs for treating the rheumatoid arthritis comprise triptolide and analgesic lidocaine hydrochloride for alleviating the pain from the rheumatoid arthritis. The film coating agent has the advantages of complete pharmacological actions, strong pertinence, long-acting pharmacological effects and simple preparation method, and can properly block the main pathological link of the development of the rheumatoid arthritis disease.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations and a preparation method, in particular to a transdermal absorption coating agent for treating rheumatoid arthritis with local analgesia and a preparation method thereof. Background technique [0002] Triptolide is a chemical component extracted from Tripterygium wilfordii of the Euonymus family. From the point of view of pharmacological effects: (1) Triptolide has both non-specific anti-inflammatory and immune effects, and mainly suppresses immune effects. (2) It has obvious inhibitory effect on acute and chronic inflammation, and is related to the pituitary system, mainly through the pituitary gland to cause the release of ACTH and enhance the secretion function of the adrenal cortex. (3) The research on adjuvant arthritis shows that it has obvious inhibitory effect on adjuvant arthritis in rats. Rat adjuvant arthritis is an animal model for studying rheumatoid drugs, and its histopat...

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Application Information

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IPC IPC(8): A61K31/585A61K31/167A61K9/00A61P29/00A61P19/04
Inventor 林绥李钢黄郑隽林苹阙慧卿彭华毅邓思珊钱丽萍连建清郭舜民齐一萍
Owner FUJIAN ACAD OF MEDICAL SCI
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