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Traditional Chinese medicine transdermal ointment for treating bovine mastitis and preparation method thereof

A technology of cow mastitis and traditional Chinese medicine, applied in ointment delivery, medical formula, medical preparations of non-active ingredients, etc., can solve the problems of reducing milk nutrition, human health hazards, prolonging postpartum estrus and pregnancy time, human health hazards, etc. , to achieve the effect of improving the body's immunity, increasing milk production and long shelf life

Inactive Publication Date: 2012-02-22
NINGXIA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the prolongation of postpartum estrus and pregnancy time caused by mastitis, the reduction of milk nutrients and the health hazards caused to humans are difficult to estimate
[0004] At present, antibiotics are generally used for treatment after mastitis occurs, which not only causes a decrease in milk production or even cessation of milk production, but also causes harm to human health due to the residual antibiotics in milk

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1) Extraction of effective components of each traditional Chinese medicine: In the following extractions: 1 part is equivalent to 50g of traditional Chinese medicine, and 1:1 liquid extract, that is, 1ml of liquid extract is equivalent to 1g of the original medicinal material.

[0022] ①Extraction of dandelion: Take 2 parts of dandelion and grind them to about 40 meshes, then put the crushed dandelions in a casserole, and cook them for 3 times according to the conventional traditional Chinese medicine cooking method, add 20 times the amount of water for the first time, and cook for 3 hours; For the second time, add 15 times the amount of water, and decoct for 2 h; for the third time, add 10 times the amount of water, and decoct for 1 h; after mixing the extraction solutions after the third decoction, place them on a rotary evaporator and concentrate to prepare 1: 1001ml of liquid extract;

[0023] ② Extraction of honeysuckle: Take 2 parts of honeysuckle and crush them t...

Embodiment 2

[0038] On the basis of the examples, the compatibility ratio and process conditions of each traditional Chinese medicine are as follows.

[0039] 1. Extraction of active ingredients of traditional Chinese medicine

[0040] (1) Water decoction:

[0041] Chinese medicine name number of copies solid to liquid ratio Extraction times extraction time dandelion 1 1:20 3 90 Whole Trichosanthes 1 1:10 3 60 angelica 1 1:10 3 60

[0042] (2) Ethanol decoction:

[0043]

[0044] 2. Compatibility of traditional Chinese medicine

[0045] Mix the above concentrated 500ml liquid extract, let it stand at room temperature for 24 hours, then place it in a centrifuge, centrifuge at 3000 rpm for 30min, collect the supernatant, discard the residue, and place the supernatant in a rotating Concentrate on the evaporator to 333ml liquid extract.

[0046] 3. Preparation of transdermal ointment

[0047] Take 8g of glyceryl monostearate, 10g of octa...

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PUM

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Abstract

The invention relates to same traditional Chinese medicines, in particular to a traditional Chinese medicine transdermal ointment for treating bovine mastitis and a preparation method thereof. The traditional Chinese medicine transdermal ointment is made of 1-2 parts of dandelion, 1-2 parts of honeysuckle, 1-2 parts of radix sophorae flavescentis, 1-2 parts of fructus forsythiae, 1-2 parts of full trichosanthes kirilowii Maxim, 1-2 parts of Angelica sinensis, 1 part of safflower carthamus, 1 part of patrinia, 1 part of akebiaquinata, 1 part of inula flower and an ointment base and a transdermal agent which are mixed. The invention is pure traditional Chinese medicine preparation and has the advantages of antibiosis, diminishing inflammation, promoting blood circulation and removing blood stasis, improving the immunity of the organism, no residual, nuisanceless, and environmental protection and the like and the compound medicine has definite curative effect. The traditional Chinese medicine transdermal ointment has stable quality and long quality guarantee period. When used for part of clinical mammitis in a cattle farm, the traditional Chinese medicine transdermal ointment is applied twice a day respectively in the morning and evening, the cure rate is about 75% after the traditional Chinese medicine transdermal ointment is continuously applied for five days; and when used fortreating hidden mammitis in the same way, the cure rate is up to about 87.5%.

Description

technical field [0001] The invention relates to some traditional Chinese medicines, in particular to a traditional Chinese medicine transdermal ointment for treating cow mastitis and a preparation method thereof. Background technique [0002] Cow mastitis (Mastitis) is a multifactorial disease, that is, inflammation of the cow's udder caused by stimulation of the cow's mammary gland by physical, chemical, microbial and other factors. The main manifestations are physical and chemical properties of milk and bacteriological changes, and pathological changes of mammary gland tissue. It is one of the most common, most difficult to control, most expensive diseases in dairy production, and seriously affects the development of the dairy industry. According to whether there are clinically visible changes in the udder and milk, cow mastitis can be divided into clinical mastitis and subclinical mastitis. [0003] According to the statistics of the World Dairy Cattle Association, there...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/634A61K9/06A61K47/44A61P15/14A61K47/22
Inventor 何生虎曹志
Owner NINGXIA UNIVERSITY