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Application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma

A technology of uterine fibroids and turning white grass, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of uterine fibroids that have not been treated, and achieve the effect of affecting the hormone level in the body and inhibiting the size

Inactive Publication Date: 2011-11-23
GUANGZHOU JIAYUAN PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
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Problems solved by technology

There is no report on the treatment of uterine fibroids

Method used

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  • Application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma
  • Application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma
  • Application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma

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Experimental program
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Effect test

Embodiment 1

[0014] 1. Experimental animal model and group administration

[0015] 60 clean-grade non-pregnant female SD rats, weighing 180-220g, were randomly divided into 5 groups, 12 rats in each group; that is, the blank group, the model group, and the high-, medium-, and low-dose groups of Panbacao water decoction. Except for the blank group, the above-mentioned animals were intramuscularly injected with 0.1 ml (0.04 mg) of diethylstilbestrol (0.04 mg) and 0.1 ml (1.0 mg) of progesterone, each once a day for 30 days. An animal model of rat uterine fibroids was established.

[0016] The water decoction of Herba Verbacula is prepared by conventional water decoction method, and concentrated to the corresponding concentration, each drug group is administered by intragastric administration, and the different dose groups of water decoction include high dose group (40g / kg), middle dose group (20g / kg ), the low-dose group (10g / kg) was administered by intragastric administration respectively,...

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Abstract

The invention discloses new application of discolor cinquefoil herb in preparation of medicines for treating hysteromyoma. The discolor cinquefoil herb is a traditional medical Chinese herb without toxic or side effect and can be prepared into medicines for patients with hysteromyoma to take for a long time.

Description

technical field [0001] The invention relates to a raw material of treating Chinese medicinal material, P. baicalensis, and specifically relates to the application of the raw material of the traditional Chinese medicine in the preparation of a drug for treating uterine fibroids. technical background [0002] Uterine fibroids are the most common benign tumors in female genitalia and one of the most common tumors in the human body. Uterine fibroids are mainly formed by the proliferation of smooth muscle cells that make up the muscle wall of the uterus, commonly known as uterine fibroids. The incidence rate of uterine fibroids is 20% in women over 30 years old, and the highest incidence rate in women aged 40-50 can be as high as 50--77%. [0003] As one of the causes of uterine fibroids, estrogen has long been noticed and extensively studied. A number of recent studies have confirmed from biochemical, clinical and pharmacological aspects that progesterone receptors also play a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61P15/00
Inventor 李维坤王桂凤王素侠
Owner GUANGZHOU JIAYUAN PHARMA TECH
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