Quilted implantable graft

A technology of surgical grafts and styles, which is applied in the direction of pharmaceutical devices, prostheses, and other medical devices, and can solve problems such as partial delamination and difficulty in suturing grafts to their proper positions.

Active Publication Date: 2011-05-11
COOK BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A potential problem with these multilayered structures is that during handling after hydration, the bonded layers sometimes partially delaminate, which can make it more difficult for the graft to be sutured into place

Method used

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  • Quilted implantable graft
  • Quilted implantable graft
  • Quilted implantable graft

Examples

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Embodiment Construction

[0025] While the invention may be embodied in many different forms, in order to facilitate an understanding of the principles of the invention, specific language will now be used to describe the embodiments shown in the drawings. However, it should be understood that they do not limit the scope of the invention. Any changes and further modifications of the described embodiments, as well as any further applications of the principles of the invention described herein, will be foreseeable to those skilled in the art to which the invention pertains.

[0026] Such as Figure 1 to Figure 9 As shown in the illustrated embodiment, the present invention includes an implantable surgical graft 10 for repairing or reinforcing tissue, wherein the graft comprises multiple layers 12 of a remodelable collagen sheet material 11, which may be obtained, for example, from an animal or thin slices of human origin obtained intact and processed to preserve the ability of the collagen matrix to remo...

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Abstract

Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

Description

[0001] References to related applications [0002] This application claims the benefit of US Provisional Patent Application No. 61 / 060,316, entitled QUILTED IMPLANTABLE GRAFT, filed June 10, 2008, which is hereby incorporated by reference in its entirety. technical field [0003] The present invention generally relates to an implantable biomaterial of natural origin for the reinforcement and / or reconstruction of natural tissue. Background technique [0004] Remodelable tissue grafts obtained as intact sheets from mammalian sources and processed to remove cellular debris advantageously retain the native structure of the extracellular matrix material (ECM). This matrix of collagen fibers provides a scaffold to aid and support tissue ingrowth, especially in porcine small intestinal submucosa or SIS (Surgisis Biodesign TM , Cook Medical, Bloomington, Indiana) in bioactive graft materials. [0005] While biomaterials from sheets advantageously retain the native structure of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/24A61L27/36A61L27/58B32B5/26
CPCA61L27/3633A61L27/50A61L27/14A61L27/38A61L27/56B32B5/26B32B5/06B32B2262/08B32B2307/7163B32B2535/00A61L27/24A61F2/0063A61F2210/0076A61F2220/0075
Inventor J·米勒U·H·帕特尔
Owner COOK BIOTECH
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