Surface-modified pyridine thioketone salt and application thereof

A technology of pyridinethione salt and surface modification, which is used in cosmetic preparations, cosmetics, hair care and other directions, can solve the problems of surface modification and modification of zinc pyrithione particles that are not reported, and achieve good lipophilicity and prolongation effect. time, enhances the effect of conditioning

Inactive Publication Date: 2011-09-14
南京枫华投资管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report on the surface modification of zinc p

Method used

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  • Surface-modified pyridine thioketone salt and application thereof
  • Surface-modified pyridine thioketone salt and application thereof
  • Surface-modified pyridine thioketone salt and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1 Surface modification of zinc pyrithione particles

[0038] Disperse 25 grams of zinc pyrithione particles in 200 grams of water, stir rapidly for 15 minutes, heat to 70°C, add 0.7 grams of cetyltrimethylammonium chloride, stir and disperse for 30 minutes, age for 2 hours, stir The temperature was lowered to 50° C., filtered, and the filter residue was dried at 70° C. and pulverized to obtain surface-modified zinc pyrithione powder.

Embodiment 2

[0039] Embodiment 2 surface modification of zinc pyrithione particles

[0040] Disperse 25 grams of zinc pyrithione particles in 200 grams of water, stir rapidly for 15 minutes, heat to 65 ° C, add 1.0 grams of sodium lauryl sulfate, stir and disperse for 30 minutes, age for 3 hours, stir and cool down to 40 ° C, Filter, dry at 80°C, and pulverize to obtain a modified powder.

Embodiment 3

[0041] Example 3 Surface modification of zinc pyrithione particles

[0042] Disperse 25 grams of zinc pyrithione particles in 200 grams of water, stir rapidly for 15 minutes, heat to 85 ° C, add 1.0 grams of ceteth dimethyl octyl ammonium chloride, stir and disperse for 30 minutes, and age After 1 hour, stir and cool down to 60°C, filter, dry at 70°C, and pulverize to obtain a modified powder.

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Abstract

The invention relates to a dandruff removing and sterilizing component commonly used in the field of daily use chemicals and discloses a surface-modified pyridine thioketone salt and application thereof. The surface-modified pyridine thioketone salt is prepared by the following steps of: dispersing a monovalent or multivalent pyridine thioketone salt which is subjected to surface modification by a surfactant into a solvent; adding a surfactant at the surface modification temperature of 40-100 DEG C; stirring fully and uniformly; ageing for 1-3 hours; lowering the temperature to 40-60 DEG C; filtering; and drying filter residues. By adopting the surface-modified pyridine thioketone salt, the fungus killing time of pyridine thioketone salt particles on the surfaces of scalps and hairs can be prolonged effectively, dandruff removing and itching relieving effects are enhanced, the phenomena of hair dryness and withering after dandruff removing shampoo is used for washing can be effectively eliminated, the hair conditioning effect is enhanced, and damaged hairs can be repaired.

Description

technical field [0001] The invention relates to an anti-dandruff and bactericidal component commonly used in the field of daily chemicals, in particular to a surface-modified pyrithione salt and an application thereof. Background technique [0002] In daily life, most adults experience the confusion of dandruff and itchy head. Usually, there are two reasons for human dandruff and itching: one is the metabolism of epidermal cells, resulting in dandruff due to cell keratinization; the other is seborrheic fungal infection adsorbed on the skin, especially Pityrosporum ovale Bacteria cause. In the patent CN200710135779.8, it is mentioned that Pityrosporum ovale enters the scalp, and the abnormal flora activity leads to the enhancement of its reproductive ability, and its anaerobic metabolism accelerates the metabolism of scalp epidermal cells, and lipase decomposes triglycerides into free The fatty acid, isolated oleic acid will lead to the formation of dandruff flakes. Curren...

Claims

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Application Information

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IPC IPC(8): C07D213/89A61K8/49A61Q5/02
Inventor 任欢鱼韦异薛虹宇李华山
Owner 南京枫华投资管理有限公司
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