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Composition for external use

A composition for external use and technology of the composition, applied in the direction of dressing preparations, medical preparations with non-active ingredients, cosmetics, etc., can solve the problems that effective ingredients are difficult to penetrate effectively, and achieve good permeability and excellent sense of use Effect

Inactive Publication Date: 2011-09-21
ROHTO PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] There are various dosage forms such as patches, ointments, creams, lotions, and solid preparations for external use on the skin. Effective ingredients do not easily penetrate into the skin effectively

Method used

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  • Composition for external use
  • Composition for external use
  • Composition for external use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0122] Formulation Example 1 Lotion

[0123]

[0124]

Embodiment 2

[0125] Preparation Example 2 Beauty Essence

[0126]

Embodiment 3

[0127] Preparation Example 3 Beauty Essence

[0128]

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PUM

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Abstract

The present invention provides a composition for external use, which comprises a component (A) and a component (B). The composition has excellent absorbility of the effect component in skin. Particularly, the composition has excellent absorbility of water-soluable effective component which is absorbed through skin and has inferior absorbility in the skin. In the composition for external use, the component (A) represents glycol ether or a derivative thereof; and component (B) represents polyhydroxy acid or a pharmaceutically acceptable salt.

Description

technical field [0001] The present invention relates to a composition for external use having excellent transdermal absorbability of active ingredients. Background technique [0002] There are various dosage forms such as patches, ointments, creams, lotions, and solid preparations for external use on the skin. Effective ingredients do not easily penetrate into the skin effectively. Therefore, various studies have been made to promote the percutaneous absorption of active ingredients of external preparations for skin and cosmetics into the skin, and several compounds that improve the percutaneous absorbability of active ingredients are known. [0003] For example, liposomes containing lecithin and hydrophilic nonionic surfactants (Patent Document 1) and absorption-promoting combinations containing phospholipids and specific polyhydric alcohols are known as external preparations for improving the transdermal absorbability of active ingredients. material (Patent Document 2) a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/14A61K47/12A61K47/10A61K8/37A61K8/365A61K8/34A61Q19/00
Inventor 矢部祐子石川敬饭塚元气
Owner ROHTO PHARM CO LTD