Apparatus and method for electrochemical detection

An electrochemical and sensor technology, applied in the direction of measuring devices, biochemical equipment and methods, medical science, etc., can solve the problems of undisclosed electrochemical substrates

Active Publication Date: 2011-11-02
UNIVERSAL BIOSENSORS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0013] Newman and Chatelier (PCT / 1B2007 / 001990) disclose counter electrodes for condensation sensors, but this disclosure is limited to the use of (im)mobility of magnetic particles to detect condensation and does not disclose electrochemical substrates

Method used

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  • Apparatus and method for electrochemical detection
  • Apparatus and method for electrochemical detection
  • Apparatus and method for electrochemical detection

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Embodiment Construction

[0022] Exemplary embodiments of the invention are discussed in detail below. While certain exemplary embodiments are discussed, it is to be understood that this is done for illustration purposes only. Those skilled in the relevant art will find that other components and structures can be used without departing from the spirit and scope of the present invention. References to "one embodiment," "an embodiment," "exemplary embodiment," "different embodiments," etc., may mean that such described embodiments of the invention may include particular features, configurations, or characteristics, but not every specific embodiment necessarily includes that particular feature, configuration or characteristic. Furthermore, repeated use of this measure "in one embodiment" or "in an exemplary embodiment" does not necessarily refer to the same embodiment, even if it were possible.

[0023] The present invention relates to a sensor having opposing electrodes (eg tool and auxiliary electrode...

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Abstract

The present invention is directed to a sensor with opposing electrodes and test strips using this sensor. The invention can be used to measure blood or plasma coagulation in assays like prothrombin time (PT) and thrombin potential, for example, in point-of-care monitoring of anticoagulants.

Description

technical field [0001] The invention relates to a sensor with opposite electrodes and a test strip using the sensor. The invention can be used, for example, in point-of-care monitoring of anticoagulants, measuring coagulation of blood or plasma in assays such as prothrombin time (PT) and thrombin potential. Background technique [0002] Various patents discuss devices and methods for detecting electrochemical substrates. For example, Jozefonvicz et al. (US Patent No. 4304853) describe the use of electrochemical substrates for the detection of proteases, including enzymes in the coagulation system. However, its approach is not practical for point-of-care settings. From the disclosure of this document it can be found that the pretreatment of the electrodes is a requirement to improve the reproducibility since the measured currents are very low. The substrate requires DMSO to assist solubility in aqueous solutions. It also discloses a 3-electrode system with sample and reag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327G01N33/49G01N33/86A61B5/00G01N33/68C12Q1/56G01N33/82
CPCG01N33/86C12Q1/56G01N33/4905A61B5/00G01N27/021G01N27/3273G01N33/48G01N27/327G01N2021/478G01N2333/974
Inventor 彼得·M·纽曼亚拉戴尔·M·哈吉斯
Owner UNIVERSAL BIOSENSORS
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