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Capsules for treating arrhythmia and preparation method thereof

A technology of arrhythmia and capsules, which is applied in the field of traditional Chinese medicine compositions, can solve problems such as lack of systematic research, and achieve the effects of promoting metabolism, preventing high blood pressure, and improving curative effect

Inactive Publication Date: 2012-01-04
朱明军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of systematic research and recognized effective antiarrhythmic Chinese patent medicines

Method used

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  • Capsules for treating arrhythmia and preparation method thereof
  • Capsules for treating arrhythmia and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0065] Embodiment 1: The capsule for the treatment of arrhythmia according to the present invention is prepared by the following weight percentages from the crude drug: Radix Glycyrrhiza, Cinnamon Twig, Keel, and Oyster:

[0066] Zhigancao 28.6%, Guizhi 14.2%, Keel 28.6%, Oyster 28.6%.

[0067] The preparation method of medicine of the present invention comprises the following steps:

[0068] (1) Take Guizhi decoction pieces, add 6 times the amount of water, soak for 12 hours, steam distill for 3 hours, extract volatile oil, and set aside; Guizhi water and medicinal residues set aside;

[0069] (2) Take the volatile oil of cassia twigs to prepare β-cyclodextrin inclusion complex by water saturation method, weigh 8 times the amount of β-cyclodextrin of the volatile oil and add water to make a saturated aqueous solution at 40°C, slowly add cassia twigs dropwise while stirring Continue stirring and inclusion of volatile oil for 1.5 hours, put it in the refrigerator at 10°C for 2...

Embodiment 2

[0073] Example 2: The capsule for treating arrhythmia according to the present invention is prepared by the following weight percentages from the raw materials: Radix Glycyrrhizae, Guizhi, Keel, and Oyster:

[0074] Zhi Licorice 40%, Guizhi 15%, Keel 25%, Oyster 20%.

[0075] The preparation method of medicine of the present invention comprises the following steps:

[0076] (1) Take Guizhi decoction pieces, add 6 times the amount of water, soak for 12 hours, steam distill for 3 hours, extract volatile oil, and set aside; Guizhi water and medicinal residues set aside;

[0077](2) Take the volatile oil of cassia twigs to prepare β-cyclodextrin inclusion complex by water saturation method, weigh 8 times the amount of β-cyclodextrin of the volatile oil and add water to make a saturated aqueous solution at 40°C, slowly add cassia twigs dropwise while stirring Continue stirring and inclusion of volatile oil for 1.5 hours, put it in the refrigerator at 10°C for 24 hours, take out t...

Embodiment 3

[0081] Example 3: The capsule for treating arrhythmia according to the present invention is prepared by the following weight percentages from the raw materials: Radix Glycyrrhizae, Guizhi, Keel, and Oyster:

[0082] Zhigancao 35%, Guizhi 20%, Keel 20%, Oyster 25%.

[0083] The preparation method of medicine of the present invention comprises the following steps:

[0084] (1) Take Guizhi decoction pieces, add 6 times the amount of water, soak for 12 hours, steam distill for 3 hours, extract volatile oil, and set aside; Guizhi water and medicinal residues set aside;

[0085] (2) Take the volatile oil of cassia twigs to prepare β-cyclodextrin inclusion complex by water saturation method, weigh 8 times the amount of β-cyclodextrin of the volatile oil and add water to make a saturated aqueous solution at 40°C, slowly add cassia twigs dropwise while stirring Continue stirring and inclusion of volatile oil for 1.5 hours, put it in the refrigerator at 10°C for 24 hours, take out th...

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Abstract

The invention discloses capsules for treating arrhythmia. The capsules are prepared from the following raw materials in percentage by weight: 28 to 40 percent of honey-fried liquoric root, 10 to 20 percent of cassia twig, 20 to 30 percent of dragon's bone and 20 to 30 percent of oyster shell. In the capsules for treating arrhythmia, the honey-fried liquoric root is used as a main medicine. The capsules have the effects of tonifying spleen, harmonizing stomach and tonifying qi and restoring pulse, and are used for weakness of spleen and stomach, malaise and fatigue, severe palpilation and pulse arrhythmia and arrhythmia such as premature beat, atrial fibrillation and the like. By means of the patch clamp technology, the study of a pharmacodynamic mechanism of the capsules for treating arrhythmia is discussed from a cell electrophysiological point of view, so that the application of the capsules is enlarged to the treatment of premature beat, atrial fibrillation and the like and the prevention of serious ventricular arrhythmia. In the capsules for treating arrhythmia, the local pathological changes of arrhythmia is emphasized, and the integral association of the capsules and whole bodies is emphasized particularly to achieve the effect of integral multilevel and multi-target regulation for multiple pathological links, so that a curative effect is improved further; and particularly the capsules have the advantages on patients who have long disease course and stubborn illness.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a Chinese patent medicine preparation for treating arrhythmias such as premature beats and atrial fibrillation. Background technique [0002] Arrhythmia is very common clinically, not only in cardiovascular diseases, but also in many non-cardiovascular diseases and a few normal healthy people. There are many types of arrhythmia, the mild ones are harmless to health, and the severe ones can lead to hemodynamic disorders; symptoms appear, and even sudden death, which is life-threatening. Arrhythmia is one of the most common causes of death and disability, accounting for approximately 11% of all natural deaths. About 300,000 people die suddenly in the United States each year, most of them from ventricular tachycardia or ventricular fibrillation (ventricular fibrillation). Therefore, prediction, prevention and treatment of arrhythmia have become one of the biggest chall...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61K9/48A61P9/06A61K35/56A61K35/02A61K35/618
Inventor 朱明军杜廷海王永霞李彬朱初麟
Owner 朱明军
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